Research

Researchers Find Source of Breast Tumor Heterogeneity and Pathway that Limits Emergence

Researchers Find Source of Breast Tumor Heterogeneity and Pathway that Limits Emergence

A team of researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center has identified mammary basal cells as a contributing source to the development of heterogeneous tumor cell subpopulations and found that activation of the PKA signaling pathway can curtail their emergence, providing opportunities for new therapeutic approaches to breast cancer.

Jankowski Receives Article of the Year Award

Jankowski Receives Article of the Year Award

Kay Jankowski, PhD, an assistant professor of psychiatry at Dartmouth’s Geisel School of Medicine, has received the Article of the Year Award for 2019 from Child Maltreatment, a leading peer-reviewed academic journal of the American Professional Society on the Abuse of Children (APSAC).

Researchers Investigate Molecule, VISTA, Which Keeps the Immune System Quiet Against Cancer

Researchers Investigate Molecule, VISTA, Which Keeps the Immune System Quiet Against Cancer

Researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center are studying a valuable target in regulating the immune response in cancer and autoimmunity. VISTA is a tempering molecule that hinders T cells in the immune system from activating against self-antigens such as cancer cells. Their new publication describes how VISTA controls T-cell responses.