Researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center are studying a valuable target in regulating the immune response in cancer and autoimmunity. VISTA is a tempering molecule that hinders T cells in the immune system from activating against self-antigens such as cancer cells. Their new publication describes how VISTA controls T-cell responses.
Researchers at Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center have discovered that a receptor found in almost all cells plays a big role in the body’s metabolism. By blocking the receptor with use of a drug, mice on a high-fat diet did not become any fatter than mice on a low-fat control diet, and obese mice dropped in weight with use of the same drug. No ill side effects were observed in either study.
People have long reported seeing flashes of light during brain radiotherapy. Until now, no one has been able to capture evidence of this sensation in humans, and only theory, models, and speculation exist to explain it. Scientists at Dartmouth’s Norris Cotton Cancer Center, for the first time, have not only caught real-time observation of this phenomenon, but explain how the light is produced in the eye when radiation passes through it.
A new study by scientists at Dartmouth’s Norris Cotton Cancer Center and the Dartmouth Institute for Health Policy and Clinical Practice conducted focus groups with women in three different states to learn what they did and did not know about breast density, in general and their own. The study found that women had varying knowledge. What they all had in common was a strong desire to learn more.
Scientists at Dartmouth’s Norris Cotton Cancer Center make a direct connection between dietary fat and cancer cell biology by showing that fat particles from the blood are taken into breast cancer cells through a novel mechanism.
Findings from a new study led by researchers at Dartmouth’s Geisel School of Medicine show that the way in which pharmaceutical companies are permitted to share information about their drugs can influence physician prescribing practices.
A $1.5M National Cancer Institute grant to Saeed Hassanpour of Dartmouth’s Norris Cotton Cancer Center will be used to build new artificial intelligence (AI) technologies for precision cancer care in lung cancer management.
Heinz Valtin, MD, emeritus professor of physiology, died at his home in Alexandria, VA, on October 11. Valtin joined the Physiology Department of Dartmouth Medical School (now Geisel School of Medicine) in 1957, eventually holding two honorary chairs, including the Andrew C. Vail Memorial Professor of Physiology, and was chair of the department from 1977–1988.
Ellen Meara, PhD, a professor of The Dartmouth Institute for Health Policy and Clinical Practice, and an adjunct professor of economics at Dartmouth College, has been elected to the prestigious National Academy of Medicine.
Scott A. Gerber, PhD, professor of molecular and systems biology and of biochemistry and cell biology at the Geisel School of Medicine at Dartmouth, and program director of the Cancer Biology and Therapeutics Research Program at Dartmouth’s Norris Cotton Cancer Center, has been named the Kenneth E. and Carol L. Weg Distinguished Professor.
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