Research

Researchers Find Source of Breast Tumor Heterogeneity and Pathway that Limits Emergence

Researchers Find Source of Breast Tumor Heterogeneity and Pathway that Limits Emergence

A team of researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center has identified mammary basal cells as a contributing source to the development of heterogeneous tumor cell subpopulations and found that activation of the PKA signaling pathway can curtail their emergence, providing opportunities for new therapeutic approaches to breast cancer.