Press Release

Researchers investigate molecule, VISTA, which keeps the immune system quiet against cancer

Researchers investigate molecule, VISTA, which keeps the immune system quiet against cancer

Researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center are studying a valuable target in regulating the immune response in cancer and autoimmunity. VISTA is a tempering molecule that hinders T cells in the immune system from activating against self-antigens such as cancer cells. Their new publication describes how VISTA controls T-cell responses.

New Mechanism May Safely Prevent and Reverse Obesity

New Mechanism May Safely Prevent and Reverse Obesity

Researchers at Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center have discovered that a receptor found in almost all cells plays a big role in the body’s metabolism. By blocking the receptor with use of a drug, mice on a high-fat diet did not become any fatter than mice on a low-fat control diet, and obese mice dropped in weight with use of the same drug. No ill side effects were observed in either study.

Scientists Capture for First Time, Light Flashes from Human Eye During Radiotherapy

Scientists Capture for First Time, Light Flashes from Human Eye During Radiotherapy

People have long reported seeing flashes of light during brain radiotherapy. Until now, no one has been able to capture evidence of this sensation in humans, and only theory, models, and speculation exist to explain it. Scientists at Dartmouth’s Norris Cotton Cancer Center, for the first time, have not only caught real-time observation of this phenomenon, but explain how the light is produced in the eye when radiation passes through it. 

Photo: National Cancer Institute (https://www.cancer.gov).

Scientists Learn What Women Know—and Don’t Know—About Breast Density and Cancer Risk

A new study by scientists at Dartmouth’s Norris Cotton Cancer Center and the Dartmouth Institute for Health Policy and Clinical Practice conducted focus groups with women in three different states to learn what they did and did not know about breast density, in general and their own. The study found that women had varying knowledge. What they all had in common was a strong desire to learn more. 

Mary Jo Turk Named the O. Ross McIntyre, MD, Professor

Mary Jo Turk Named the O. Ross McIntyre, MD, Professor

Mary Jo Turk, PhD, has been named the O. Ross McIntyre, MD, Professor at the Geisel School of Medicine at Dartmouth. Turk, a professor of microbiology and immunology and co-director of the Immunology and Cancer Immunotherapy Program at Dartmouth’s Norris Cotton Cancer Center, joined the faculty of Dartmouth’s medical school 15 years ago and conducts pioneering research on the complex interactions between the immune system and cancer.

Nicole Borges Named Chair of the Department of Medical Education

Nicole Borges Named Chair of the Department of Medical Education

Nicole J. Borges, PhD, a professor of neurobiology and anatomical sciences at the University of Mississippi Medical Center, has been named Chair of the Department of Medical Education at Dartmouth’s Geisel School of Medicine. Borges, a health psychologist with over 20 years of experience in medical education, is recognized nationally for her scholarly approaches to student and faculty advancement.

O’Toole Named the Elmer R. Pfefferkorn, PhD, Professor of Microbiology and Immunology

O’Toole Named the Elmer R. Pfefferkorn, PhD, Professor of Microbiology and Immunology

George O’Toole, PhD, a professor of microbiology and immunology at Dartmouth’s Geisel School of Medicine, has been named the Elmer R. Pfefferkorn, PhD, Professor of Microbiology and Immunology at Geisel. The appointment recognizes O’Toole’s outstanding contributions to microbiology and immunology both as a scientist and mentor to students over his 20-year career at Dartmouth.