Press Release

Geisel Med Student Alyssa Flores ’21 Leads Study Published in Nature Nanotechnology

Geisel Med Student Alyssa Flores ’21 Leads Study Published in Nature Nanotechnology

During two exciting years as a Howard Hughes Medical Institute (HHMI) Research Fellow, Alyssa Flores ’21 immersed herself in translational research in the lab of Nicholas Leeper, MD, director of vascular research and chief of vascular medicine at Stanford University; was lead author of a paper published in the journal Circulation; and had lunch with a Nobel Laureate. Now back at Geisel, Flores is lead author of a new paper published today in the journal Nature Nanotechnology.

Researchers Investigate Molecule, VISTA, Which Keeps the Immune System Quiet Against Cancer

Researchers Investigate Molecule, VISTA, Which Keeps the Immune System Quiet Against Cancer

Researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center are studying a valuable target in regulating the immune response in cancer and autoimmunity. VISTA is a tempering molecule that hinders T cells in the immune system from activating against self-antigens such as cancer cells. Their new publication describes how VISTA controls T-cell responses.

New Mechanism May Safely Prevent and Reverse Obesity

New Mechanism May Safely Prevent and Reverse Obesity

Researchers at Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center have discovered that a receptor found in almost all cells plays a big role in the body’s metabolism. By blocking the receptor with use of a drug, mice on a high-fat diet did not become any fatter than mice on a low-fat control diet, and obese mice dropped in weight with use of the same drug. No ill side effects were observed in either study.