COVID-19 Information

DartLab Presentations

Peer-reviewed Publications with DartLab Co-Authors:

Farzan SF, Howe CG, Zens MS, Palys T, Channon JY, Li Z, Chen Y, Karagas MR. Urine Arsenic and Arsenic Metabolites in U.S. Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study. Environ Health Perspect. 2017; 125:127002. PMID: 29373859.

Howe CG, Li Z, Zens MS, Palys T, Chen Y, Channon JY, Karagas MR, Farzan SF. Dietary B Vitamin Intake Is Associated with Lower Urinary Monomethyl Arsenic and Oxidative Stress Marker 15-F(2t)-Isoprostane among New Hampshire Adults. J Nutr. 2017; 147:2289-2296. PMID: 29070711.

Pant AB, Wang Y, Mielcarz DW, Kasper EJ, Telesford KM, Mishra M, Haque A, Channon JY, Kasper LH, Begum-Haque S. Alteration of CD39+Foxp3+ CD4 T cell and cytokine levels in EAE/MS following anti-CD52 treatment. J Neuroimmunol. 2017; 303:22-30. PMID: 28087077.

Koeppen K, Hampton TH, Jarek M, Scharfe M, Gerber SA, Mielcarz DW, Demers EG, Dolben EL, Hammond JH, Hogan DA, Stanton BA. A Novel Mechanism of Host-Pathogen PLoS Pathog. 2016; e1005672.

Talebian L, Fischer DA, Wu J, Channon JY, Sentman CL, Ernstoff MS, Meehan KR. The natural killer-activating receptor, NKG2D, on CD3+CD8+ T cells plays a critical role in identifying and killing autologous myeloma cells. Transfusion. 2014; 54:1515-21. PMID: 24446786.

Barth RJ Jr, Fisher DA, Wallace PK, Channon JY, Noelle RJ, Gui J, Ernstoff MS. A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival. Clin Cancer Res. 2010; 16:5548-56. PMID: 20884622.

Talebian L, Coutermarsh B, Channon JY, Stanton BA. Corr4A and VRT325 do not reduce the inflammatory response to P. aeruginosa in human cystic fibrosis airway epithelial cells. Cell Physiol Biochem. 2009; 23:199-204. PMID: 19255514

Fahey JV, Schaefer TM, Channon JY, Wira CR. Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract. Hum Reprod. 2005; 20:1439-46. PMID: 15734755.

Oral Presentations:

New England Immunology Conference (2018)

Panelist: J. Channon (Flow Cytometry)

CYTO 2017 (International Flow Cytometry Conference)

Characterization and Utilization of the ZE5 for Human Immune Monitoring

D. Mielcarz, A. Bergeron, G. Ward, R. Andreozzi and J. Channon.

(Presentation sponsored by Bio-Rad, Inc.)

ZE5/YETI Early Access User Meeting (2016)

Characterization of the YETI flow cytometer for use in an immune monitoring laboratory.

Mielcarz, A. Bergeron, G. Ward, R. Andreozzi, J. Channon.

(Sponsored by Propel Labs, Inc.)

New England Immunology Conference (2015)

Panelist: J. Channon (Flow Cytometry)

Alemtuzumab Treatment Dramatically Alters T and B Cell Frequency and Phenotype in Relapsing-Remitting MS Patients

D. Mielcarz, J. DeLong, A. Bergeron, G. Ward, L. Janney, L. Kasper and J. Channon.

XXVIII Congress of the International Society for Advancement of Cytometry (2013)

Relapsing-Remitting MS Patients Have Significant Differences in Circulating B
Cells Subset and Phenotype Compared with Healthy Controls, and IFNβ-1b Treatment Can Alter the Composition and Phenotype of These Subsets

D. Mielcarz, J. DeLong, A. Bergeron, K. Smith, A. Heyn, L. Kasper and J. Channon.

Immunology 2012 (99th Annual Meeting of the American Association of Immunologists)

IFNbeta-1b alters the composition of circulating B cell subsets, and leads to changes in the B cell cytokine secretion profile in patients with relapsing-remitting multiple sclerosis.

D. Mielcarz, A. Bergeron, J. DeLong, K. Smith, A. Heyn, K. Mack, M.A. Conrad, B. Oliver, L. Kasper, and J. Channon

Posters:

FOCIS (2018)

Development of 12+ Color Modular Staining Panels with a Common Backbone to Interrogate CD40L-based Activation of Human B Cells, PBMC, Neutrophils and Monocyte-derived Dendritic Cells

Daniel Mielcarz, Alan Bergeron, Mikayla Kravetz, Ryan Andreozzi, Andrew Calkins, Randolph Noelle, Jay Rothstein, Xinming Cai, Catherine Jones, Sambasiva Rao, Frank Nestle and Jacqueline Channon

Annual Meeting of the American Academy of Neurology (2016)

The Retinoid Receptor (RXR) Selective Agonist IRX4204 Promotes Differentiation of Human aTreg Cells and Inhibits Differentiation of Human Th17 Cells

Mielcarz, A. Bergeron, J. DeLong, R. Andreozzi, E. Nowak, R. Chandraratna, M. Sanders, R. Noelle, J. Channon.

Northeast Regional Life Sciences Core Directors (2016)

DartLab: Immune monitoring and Flow Cytometry Shared Resource

Mielcarz, A. Bergeron, G. Ward, R. Andreozzi, J. Channon.

Northeast Regional Life Sciences Core Directors (2015)

IRX4204, a novel RXR agonist, alters cytokine secretion of T cells and monocytes, and increases in vitro adaptive T regulatory cell proliferation

D. Mielcarz, J. DeLong, R. Andreozzi, A. Bergeron, G. Ward, L. Kasper and J. Channon.

XXIX Congress of the International Society for Advancement of Cytometry (2014)

Alemtuzumab Treatment Dramatically Alters T and B Cell Frequency and Phenotype in Relapsing- Remitting MS Patients

D. Mielcarz, J. DeLong, A.J. Bergeron, N. Martin, L. Kasper and J. Channon.

XXIX Congress of the International Society for Advancement of Cytometry (2014)

Development of an 8-Color Human Regulatory T-Cell Extracellular Staining Panel Using Commercially Available Fluorophore-Conjugated Antibodies

J. DeLong, D. Mielcarz, A.J. Bergeron, G. Ward, N. Martin and J. Channon.

XXIX Congress of the International Society for Advancement of Cytometry (2014)

Flow Cytometer Assurance in a Multi-Instrument Shared Resource

G. Ward, N. Martin, A. Bergeron, D. Mielcarz, J. Delong and J. Channon.

29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (2013)

Anti-CD52 therapy induces significant changes in T and B cell subset frequency and cytokine expression by B cells in multiple sclerosis patients

D. Mielcarz, A. Bergeron, J. DeLong, C. Sears, R. Grady, J. Channon, L. Kasper

64th Annual Meeting of the American Academy of Neurology (2012)

IFNβ-1b Treatment Alters the Composition of Circulating B Cell Subsets, In Particular Reducing the Number of Autoantibody Secreting B1 Cells in Patients with Relapsing-Remitting Multiple Sclerosis

D. Mielcarz, A. Bergeron, J. DeLong, K. Smith, A. Heyn, K. Mack, M.A. Conrad, B. Oliver, L. Kasper, and J. Channon