A research team at Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center has found that the same vaccination programs that target human papillomavirus (hrHPV) strains in the United States may not be as effective in protecting other populations of women from the disease.
$15.5 million NCI grant continues support for northern New England’s only comprehensive center.
Dartmouth researchers have created an AI model to classify colorectal polyps on histology slides. Evaluation using 238 slides from 24 institutions across 13 US states finds that the model performs as well as practicing pathologists.
A common anti-diabetes drug being tested in many clinical trials as an anti-cancer agent activated fat metabolism that promoted the survival of dormant breast cancer cells, suggesting that the drug has context-dependent effects on cancer cells.
Using specialty cameras and an oxygen probe drug injection, researchers at Dartmouth’s Norris Cotton Cancer Center can now image oxygen from within cancer tumors during radiation therapy while the probe is excited by Cherenkov light, a byproduct of radiation.
Researchers led by Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center are studying a valuable target in regulating the immune response in cancer and autoimmunity. VISTA is a tempering molecule that hinders T cells in the immune system from activating against self-antigens such as cancer cells. Their new publication describes how VISTA controls T-cell responses.
Researchers at Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center have discovered that a receptor found in almost all cells plays a big role in the body’s metabolism. By blocking the receptor with use of a drug, mice on a high-fat diet did not become any fatter than mice on a low-fat control diet, and obese mice dropped in weight with use of the same drug. No ill side effects were observed in either study.
A new study by scientists at Dartmouth’s Norris Cotton Cancer Center and the Dartmouth Institute for Health Policy and Clinical Practice conducted focus groups with women in three different states to learn what they did and did not know about breast density, in general and their own. The study found that women had varying knowledge. What they all had in common was a strong desire to learn more.
Scientists at Dartmouth’s Norris Cotton Cancer Center make a direct connection between dietary fat and cancer cell biology by showing that fat particles from the blood are taken into breast cancer cells through a novel mechanism.
Mary Jo Turk, PhD, has been named the O. Ross McIntyre, MD, Professor at the Geisel School of Medicine at Dartmouth. Turk, a professor of microbiology and immunology and co-director of the Immunology and Cancer Immunotherapy Program at Dartmouth’s Norris Cotton Cancer Center, joined the faculty of Dartmouth’s medical school 15 years ago and conducts pioneering research on the complex interactions between the immune system and cancer.
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