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J. Andrew Daubenspeck, BS, PhD

Title(s)
Emeritus Professor of Physiology and Neurobiology

Department(s)
Physiology and Neurobiology

Education
Swarthmore College, BSME, 1966
Dartmouth College, Ph.D. Engineering Science, 1972

Programs
Program in Experimental and Molecular Medicine

Websites
http://dms.dartmouth.edu/physio/

Contact Information

351 Poverty Lane
Lebanon NH 03766

Phone: 603/448-2855
Email: andy.daubenspeck@dartmouth.edu


Professional Interests

Dr. Daubenspeck became Active Emeritus in 2011 and continued teaching cardiopulmonary physiology to first year medical students until 2016. Since then, he has collaborated with Dr. James Leiter and Dr. Brian Lucas on a project involving mathematical simulation of body fluid shifts during dialysis in patients suffering from volume overload due to cardiac and renal causes. The goal is to optimize the removal of fluid from the vascular volume under the constraints of time of dialysis and patient comfort.


Selected Publications

 

Relative Blood Volume Profiles Hours After Loop Diuretic Administration: A Systematic Review and Meta-analysis.
Lucas BP, Misra S, Donnelly WT, Daubenspeck JA, Leiter JC
CJC Open. 2023 Aug;5(8):641-649. doi: 10.1016/j.cjco.2023.05.003. Epub 2023 May 18.
PMID: 37720179

Pituitary adenylate cyclase-activating polypeptide drives cardiorespiratory responses to heat stress in neonatal mice.
Barrett KT, Daubenspeck JA, Wilson RJA
Am J Physiol Regul Integr Comp Physiol. 2017 Oct 1;313(4):R385-R394. doi: 10.1152/ajpregu.00118.2017. Epub 2017 Jul 12.
PMID: 28701321

Partial Raphe Dysfunction in Neurotransmission Is Sufficient to Increase Mortality after Anoxic Exposures in Mice at a Critical Period in Postnatal Development.
Barrett KT, Dosumu-Johnson RT, Daubenspeck JA, Brust RD, Kreouzis V, Kim JC, Li A, Dymecki SM, Nattie EE
J Neurosci. 2016 Apr 6;36(14):3943-53. doi: 10.1523/JNEUROSCI.1796-15.2016.
PMID: 27053202

Subtle alterations in breathing and heart rate control in the 5-HT1A receptor knockout mouse in early postnatal development.
Barrett KT, Kinney HC, Li A, Daubenspeck JA, Leiter JC, Nattie EE
J Appl Physiol (1985). 2012 Nov;113(10):1585-93. doi: 10.1152/japplphysiol.00939.2012. Epub 2012 Aug 30.
PMID: 22936722

Postnatal loss of brainstem serotonin neurones compromises the ability of neonatal rats to survive episodic severe hypoxia.
Cummings KJ, Hewitt JC, Li A, Daubenspeck JA, Nattie EE
J Physiol. 2011 Nov 1;589(Pt 21):5247-56. doi: 10.1113/jphysiol.2011.214445. Epub 2011 Sep 12.
PMID: 21911619

Failed heart rate recovery at a critical age in 5-HT-deficient mice exposed to episodic anoxia: implications for SIDS.
Cummings KJ, Commons KG, Hewitt JC, Daubenspeck JA, Li A, Kinney HC, Nattie EE
J Appl Physiol (1985). 2011 Sep;111(3):825-33. doi: 10.1152/japplphysiol.00336.2011. Epub 2011 Jun 16.
PMID: 21680874

Toward feedback controlled deep brain stimulation: dynamics of glutamate release in the subthalamic nucleus in rats.
Behrend CE, Cassim SM, Pallone MJ, Daubenspeck JA, Hartov A, Roberts DW, Leiter JC
J Neurosci Methods. 2009 Jun 15;180(2):278-89. doi: 10.1016/j.jneumeth.2009.04.001. Epub 2009 Apr 11.
PMID: 19464518

Acoustic plethysmography measures breathing in unrestrained neonatal mice.
Daubenspeck JA, Li A, Nattie EE
J Appl Physiol (1985). 2008 Jan;104(1):262-8. Epub 2007 Oct 25.
PMID: 17962574

A computational analysis of central CO2 chemosensitivity in Helix aspersa.
Chernov MM, Daubenspeck JA, Denton JS, Pfeiffer JR, Putnam RW, Leiter JC
Am J Physiol Cell Physiol. 2007 Jan;292(1):C278-91. Epub 2006 Aug 23.
PMID: 16928773

Reduced respiratory-related evoked activity in subjects with obstructive sleep apnea syndrome.
Akay M, Leiter JC, Daubenspeck JA
J Appl Physiol (1985). 2003 Feb;94(2):429-38. Epub 2002 Dec 20.
PMID: 12496135

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