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Kimberley S Samkoe, PhD

Assistant Professor of Surgery
Adjunct Assistant Professor at Thayer School of Engineering


Ph.D. - 2007 - Biophysical Chemistry, University of Calgary, Calgary, AB, Canada
B.Sc.Hons. - 2001 - Biochemsitry, University of Regina, Regina, SK, Canada

Norris Cotton Cancer Center


Contact Information:

536E Borwell
One Medical Center Drive
Dartmouth Hitchcock Memorial Center
Lebanon NH 03756

Office: 536E Borwell
Phone: 603-650-7618
Email: Kimberley.S.Samkoe@Dartmouth.edu

Selected Publications:


Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success.
Pogue BW, Elliott JT, Kanick SC, Davis SC, Samkoe KS, Maytin EV, Pereira SP, Hasan T
Phys Med Biol. 2016 Apr 7;61(7):R57-89. doi: 10.1088/0031-9155/61/7/R57. Epub 2016 Mar 10.
PMID: 26961864

Image-derived arterial input function for quantitative fluorescence imaging of receptor-drug binding in vivo.
Elliott JT, Samkoe KS, Davis SC, Gunn JR, Paulsen KD, Roberts DW, Pogue BW
J Biophotonics. 2016 Mar;9(3):282-95. doi: 10.1002/jbio.201500162. Epub 2015 Sep 9.
PMID: 26349671

Advancing Molecular-Guided Surgery through probe development and testing in a moderate cost evaluation pipeline.
Pogue BW, Paulsen KD, Hull SM, Samkoe KS, Gunn J, Hoopes J, Roberts DW, Strong TV, Draney D, Feldwisch J
Proc SPIE Int Soc Opt Eng. 2015 Mar 4;9311 pii: 931112.
PMID: 25914500

Nodal lymph flow quantified with afferent vessel input function allows differentiation between normal and cancer-bearing nodes.
DSouza AV, Elliott JT, Gunn JR, Barth RJ Jr, Samkoe KS, Tichauer KM, Pogue BW
Biomed Opt Express. 2015 Apr 1;6(4):1304-17. doi: 10.1364/BOE.6.001304. Epub 2015 Mar 17.
PMID: 25909014

Perfusion CT estimates photosensitizer uptake and biodistribution in a rabbit orthotopic pancreatic cancer model: a pilot study.
Elliott JT, Samkoe KS, Gunn JR, Stewart EE, Gardner TB, Tichauer KM, Lee TY, Hoopes PJ, Pereira SP, Hasan T, Pogue BW
Acad Radiol. 2015 May;22(5):572-9. doi: 10.1016/j.acra.2014.12.014. Epub 2015 Feb 14.
PMID: 25683500

Tomography of epidermal growth factor receptor binding to fluorescent Affibody in vivo studied with magnetic resonance guided fluorescence recovery in varying orthotopic glioma sizes.
Holt RW, Demers JL, Sexton KJ, Gunn JR, Davis SC, Samkoe KS, Pogue BW
J Biomed Opt. 2015 Feb;20(2):26001. doi: 10.1117/1.JBO.20.2.026001.
PMID: 25652703

Comparison of Kinetic Models for Dual-Tracer Receptor Concentration Imaging in Tumors.
Hamzei N, Samkoe KS, Elliott JT, Holt RW, Gunn JR, Hasan T, Pogue BW, Tichauer KM
Austin J Biomed Eng. 2014 Mar 5;1(1) pii: austinpublishinggroup.com/biomedical-engineering/fulltext/ajbe-v1-id1002.php.
PMID: 25414912

Pixel-based absorption correction for dual-tracer fluorescence imaging of receptor binding potential.
Kanick SC, Tichauer KM, Gunn J, Samkoe KS, Pogue BW
Biomed Opt Express. 2014 Oct 1;5(10):3280-91. doi: 10.1364/BOE.5.003280. Epub 2014 Aug 29.
PMID: 25360349

Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging.
Tichauer KM, Samkoe KS, Gunn JR, Kanick SC, Hoopes PJ, Barth RJ, Kaufman PA, Hasan T, Pogue BW
Nat Med. 2014 Nov;20(11):1348-53. doi: 10.1038/nm.3732. Epub 2014 Oct 26.
PMID: 25344739

Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach.
Samkoe KS, Tichauer KM, Gunn JR, Wells WA, Hasan T, Pogue BW
Cancer Res. 2014 Dec 15;74(24):7465-74. doi: 10.1158/0008-5472.CAN-14-0141. Epub 2014 Oct 24.
PMID: 25344226