Kimberley S Samkoe, PhD

Assistant Professor of Surgery
Adjunct Assistant Professor at Thayer School of Engineering


Ph.D. - 2007 - Biophysical Chemistry, University of Calgary, Calgary, AB, Canada
B.Sc.Hons. - 2001 - Biochemsitry, University of Regina, Regina, SK, Canada

Norris Cotton Cancer Center


Contact Information:

536E Borwell
One Medical Center Drive
Dartmouth Hitchcock Memorial Center
Lebanon NH 03756

Office: 536E Borwell
Phone: 603-650-7618

Selected Publications:


Optical tracer size differences allow quantitation of active pumping rate versus Stokes-Einstein diffusion in lymphatic transport.
DSouza AV, Marra K, Gunn JR, Samkoe KS, Pogue BW
J Biomed Opt. 2016 Oct 1;21(10):100501. doi: 10.1117/1.JBO.21.10.100501.
PMID: 27752703

Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
de Souza AL, Marra K, Gunn J, Samkoe KS, Kanick SC, Davis SC, Chapman MS, Maytin EV, Hasan T, Pogue BW
Br J Cancer. 2016 Sep 27;115(7):805-13. doi: 10.1038/bjc.2016.267. Epub 2016 Aug 30.
PMID: 27575852

Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging.
DSouza AV, Lin H, Henderson ER, Samkoe KS, Pogue BW
J Biomed Opt. 2016 Aug 1;21(8):80901. doi: 10.1117/1.JBO.21.8.080901.
PMID: 27533438

Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions.
de Souza AL, Marra K, Gunn J, Samkoe KS, Hoopes PJ, Feldwisch J, Paulsen KD, Pogue BW
Mol Imaging Biol. 2016 Jul 5; Epub 2016 Jul 5.
PMID: 27379987

Vision 20/20: Molecular-guided surgical oncology based upon tumor metabolism or immunologic phenotype: Technological pathways for point of care imaging and intervention.
Pogue BW, Paulsen KD, Samkoe KS, Elliott JT, Hasan T, Strong TV, Draney DR, Feldwisch J
Med Phys. 2016 Jun;43(6):3143. doi: 10.1118/1.4951732.
PMID: 27277060

Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success.
Pogue BW, Elliott JT, Kanick SC, Davis SC, Samkoe KS, Maytin EV, Pereira SP, Hasan T
Phys Med Biol. 2016 Apr 7;61(7):R57-89. doi: 10.1088/0031-9155/61/7/R57. Epub 2016 Mar 10.
PMID: 26961864

Image-derived arterial input function for quantitative fluorescence imaging of receptor-drug binding in vivo.
Elliott JT, Samkoe KS, Davis SC, Gunn JR, Paulsen KD, Roberts DW, Pogue BW
J Biophotonics. 2016 Mar;9(3):282-95. doi: 10.1002/jbio.201500162. Epub 2015 Sep 9.
PMID: 26349671

Advancing Molecular-Guided Surgery through probe development and testing in a moderate cost evaluation pipeline.
Pogue BW, Paulsen KD, Hull SM, Samkoe KS, Gunn J, Hoopes J, Roberts DW, Strong TV, Draney D, Feldwisch J
Proc SPIE Int Soc Opt Eng. 2015 Mar 4;9311 pii: 931112.
PMID: 25914500

Nodal lymph flow quantified with afferent vessel input function allows differentiation between normal and cancer-bearing nodes.
DSouza AV, Elliott JT, Gunn JR, Barth RJ Jr, Samkoe KS, Tichauer KM, Pogue BW
Biomed Opt Express. 2015 Mar 17;6(4):1304-17. doi: 10.1364/BOE.6.001304. Epub 2015 Mar 17.
PMID: 25909014

Perfusion CT estimates photosensitizer uptake and biodistribution in a rabbit orthotopic pancreatic cancer model: a pilot study.
Elliott JT, Samkoe KS, Gunn JR, Stewart EE, Gardner TB, Tichauer KM, Lee TY, Hoopes PJ, Pereira SP, Hasan T, Pogue BW
Acad Radiol. 2015 May;22(5):572-9. doi: 10.1016/j.acra.2014.12.014. Epub 2015 Feb 14.
PMID: 25683500