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Kimberley S Samkoe, Ph.D.

Title(s):
Assistant Professor of Surgery
Adjunct Assistant Professor at Thayer School of Engineering

Department(s):
Surgery

Education:
Ph.D. - 2007 - Biophysical Chemistry, University of Calgary, Calgary, AB, Canada
B.Sc.Hons. - 2001 - Biochemsitry, University of Regina, Regina, SK, Canada

Programs:
Norris Cotton Cancer Center

Websites:
http://www.dartmouth.edu/optmed/
http://www.photobiology.org/

Contact Information:

536E Borwell
One Medical Center Drive
Dartmouth Hitchcock Memorial Center
Lebanon NH 03756

Office: 536E Borwell
Phone: 603-650-7618
Email: Kimberley.S.Samkoe@Dartmouth.edu

Selected Publications:
 

Davis SC, Samkoe KS, Tichauer KM, Sexton KJ, Gunn JR, Deharvengt SJ, Hasan T, Pogue BW
Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo.
Proc Natl Acad Sci U S A 2013 May 28; 110(22):9025-30
PMID: 23671066

Sexton K, Tichauer K, Samkoe KS, Gunn J, Hoopes PJ, Pogue BW
Fluorescent affibody peptide penetration in glioma margin is superior to full antibody.
PLoS One 2013; 8(4):e60390
PMID: 23593208

Tichauer KM, Holt RW, El-Ghussein F, Davis SC, Samkoe KS, Gunn JR, Leblond F, Pogue BW
Dual-tracer background subtraction approach for fluorescent molecular tomography.
J Biomed Opt 2013 Jan; 18(1):16003
PMID: 23292612

Tichauer KM, Samkoe KS, Klubben WS, Hasan T, Pogue BW
Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors.
Phys Med Biol 2012 Oct 21; 57(20):6647-59
PMID: 23022732

Tichauer KM, Holt RW, Samkoe KS, El-Ghussein F, Gunn JR, Jermyn M, Dehghani H, Leblond F, Pogue BW
Computed tomography-guided time-domain diffuse fluorescence tomography in small animals for localization of cancer biomarkers.
J Vis Exp 2012 Jul 17; (65):e4050
PMID: 22847515

Torosean S, Flynn B, Axelsson J, Gunn J, Samkoe KS, Hasan T, Doyley MM, Pogue BW
Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure.
Nanomedicine 2013 Feb; 9(2):151-8
PMID: 22841910

Tichauer KM, Samkoe KS, Sexton KJ, Gunn JR, Hasan T, Pogue BW
Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging.
J Biomed Opt 2012 Jun; 17(6):066001
PMID: 22734757

Tichauer KM, Samkoe KS, Sexton KJ, Hextrum SK, Yang HH, Klubben WS, Gunn JR, Hasan T, Pogue BW
In vivo quantification of tumor receptor binding potential with dual-reporter molecular imaging.
Mol Imaging Biol 2012 Oct; 14(5):584-92
PMID: 22203241

Samkoe KS, Gibbs-Strauss SL, Yang HH, Khan Hekmatyar S, Jack Hoopes P, O'Hara JA, Kauppinen RA, Pogue BW
Protoporphyrin IX fluorescence contrast in invasive glioblastomas is linearly correlated with Gd enhanced magnetic resonance image contrast but has higher diagnostic accuracy.
J Biomed Opt 2011 Sep; 16(9):096008
PMID: 21950922

Samkoe KS, Sexton K, Tichauer KM, Hextrum SK, Pardesi O, Davis SC, O'Hara JA, Hoopes PJ, Hasan T, Pogue BW
High vascular delivery of EGF, but low receptor binding rate is observed in AsPC-1 tumors as compared to normal pancreas.
Mol Imaging Biol 2012 Aug; 14(4):472-9
PMID: 21847690