Edit Entry

Gregory J. Tsongalis, Ph.D.

Professor of Pathology
Director, Molecular Pathology
Co-Director, Translational Research Program and Patholgy Shared Resource


Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine

Contact Information:

Department of Pathology
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: Borwell, 538W
Phone: 603-650-5498
Fax: 603-650-6120
Email: Gregory.J.Tsongalis@hitchcock.org

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email: amber.j.erskine@hitchcock.org

Professional Interests:

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information:

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732

Selected Publications:


  • Schink JC, Trosman JR, Weldon CB, Siziopikou KP, Tsongalis GJ, et al. Biomarker testing for breast, lung, and gastroesophageal cancers at NCI designated cancer centers. JNCI 2014, in press (view details on MedLine)

  • Burchard PR, Abou Tayoun AN, Scherer A, Tsongalis GJ A rapid RT-PCR assay for the detection of HIV-1 in human plasma specimens. Exp Molec Pathol 2014, in press. (view details on MedLine)

  • Tafe LJ, Cao J, Sabbath-Solitare M, Redondo TC, Lara J, Tsongalis GJ HER2 testing in gastroesophageal cancer paired biopsy and resection specimens A multi- institutional immunohistochemistry and fluorescence in-situ hybridization correlation. J Clin Exp Oncol 2014

  • De Abreu FB, Gallagher TL, Liu EZ, Tsongalis GJ Determining methylation status of methylguanine DNA methyl transferase (MGMT) from formalin-fixed, paraffin embedded tumor tissue. Methods X 2014, July, 1:42-48.

  • Liu X, Mody K, de Abreu FB, Pipas JM, Peterson JD, Gallagher TL, et al. Molecular profiling of appendiceal epithelial tumors using massively parallel sequencing to identify somatic mutations. Clin Chem 2014, Jul;60(7):1004-11 (view details on MedLine)

  • Korf BR, Berry AB, Limson M, Marian AJ, Murray MF, O'Rourke PP, Passamani ER, Relling MV, Tooker J, Tsongalis GJ, Rodriguez LL. Framework for development of physician competencies in genomic medicine: report of the Competencies Working Group of the Inter-Society Coordinating Committee for Physician Education in Genomics. Genet Med. 2014 Apr 24 (ahead of print). (view details on MedLine)

  • Brand RE, Adai AT, Centeno BA, , Lee LS, Rateb G, Vignesh S, et al A MicroRNA-based test improves endoscopic ultrasound-guided cytologic diagnosis of pancreatic cancer. Clin Gastroenterol Hepatol, Oct;12(10):1717-23, 2014. (view details on MedLine)

  • Cervinski MA, Sam S, Steinmetz HB, Wood B, Tsongalis GJ Validation of an Interleukin 28B Genotyping Assay for Clinical Use. Clin Biochem 2014 Apr; 47(6):478-480. (view details on MedLine)

  • Tsongalis GJ, Peterson JD, de Abreu F, Tunkey CD, Gallagher TL, Strausbaugh LD, Wells WA, Amos CI. Routine Use of the Ion Torrent AmpliSeqTM Cancer Hotspot Panel for Identification of Clinically Actionable Somatic Mutations. Clin Chem Lab Med Dec 2014 May;52(5):707-714. (view details on MedLine)

  • Koestler DC, Li J, Baron JA, Tsongalis GJ, Butterly LF, Goodrich M, Lesseur C, Karagas MR, Marsit CJ, Moore JH, Andrew AS, Srivastava A. Distinct patterns of DNA methylation in conventional adenomas involving the right and left colon. Mod Pathol. 2014 Jan;27(1):145-55. (view details on MedLine)