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Angeline S. Andrew, Ph.D.

Title(s):
Assistant Professor of Community and Family Medicine
Section of Epidemiology and Biostatistics, Department of Community and Family Medicine

Department(s):
Community and Family Medicine

Education:
Dartmouth Medical School, PHD 2001
Tufts University, BS 1996

Programs:
Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine
Quantitative Biomedical Sciences

Websites:
http://dms.dartmouth.edu/pemm/faculty/a-l/

Contact Information:

7927 Rubin Building, Room 860
One Medical Center Drive
Lebanon NH 03756

Office: Rubin 860
Phone: (603) 653-9019
Fax: (603) 653-9093
Email: Angeline.Andrew@dartmouth.edu

Assistant: Crystal Flaherty
Asst. Phone: (603) 653-9022
Asst. Email: Crystal.M.Flaherty@Dartmouth.edu


Professional Interests:

Translating molecular toxicology into human populations; identifying host genetic factors that modify cancer prognosis and response to environmental exposures; interactions between multiple stressors.

Rotations and Thesis Projects:

Mechanisms of arsenic immunosuppression. MicroRNA markers of bladder cancer prognosis. Genetic predictors of bladder cancer prognosis.

Grant Information:

- 3R01CA131141 (Dietrich) Variations in Colonoscopy Screening: a population based study. NIH/NCI APRC Supplement, Andrew 7/1/09-6/30/11 New Hampshire Colonoscopy Registry Collaborative Research. Molecular Epidemiology of Cancer Laboratory.

- 1K07CA102327 Andrew 9/1/05 - 8/31/11
NIH/NCI Bladder Cancer Prognostic Indicators

- 5 P42 ES07373 (Stanton) 4/1/08 3/31/13 NIH/NIEHS Toxic Metals in the Northeast: From Biological to Environmental Implications. Co-Investigator: Integrated Biology Core (Moore).

Courses Taught:

Lecturer, Cancer Biology; Lecturer, Graduate Toxicology; Lecturer, Current Approaches in Experimental Therapeutics; Small group leader, DMS Epidemiology and Biostatistics.


Selected Publications:

 

  • Andrew AS, Burgess JL, Meza MM, Demidenko E, Waugh MG, Hamilton JW, Karagas MR. Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Environ Health Perspect. 2006 Aug;114(8):1193-8. (view details on MedLine)

  • Andrew AS, Nelson HH, Kelsey KT, Moore JH, Meng AC, Casella DP, Tosteson TD, Schned AR, Karagas MR. Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility. Carcinogenesis. 2006 May;27(5):1030-7. Epub 2005 Nov 25. (view details on MedLine)

  • Andrew AS, Bernardo V, Warnke LA, Davey JC, Hampton T, Mason RA, Thorpe JE, Ihnat MA, Hamilton JW. Exposure to arsenic at levels found inU.S. drinking water modifies expression in the mouse lung. Toxicol Sci. 2007 Nov;100(1):75-87. Epub 2007 Aug 6. (view details on MedLine)

  • Andrew AS, Karagas MR, Nelson HH, Guarrera S, Polidoro S, Gamberini S, Sacerdote C, Moore JH, Kelsey KT, Demidenko E, Vineis P, Matullo G. DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy. Hum Hered. 2008;65(2):105-18. Epub 2007 Sep 26. (view details on MedLine)

  • Andrew AS, Jewell DA, Mason RA, Whitfield ML, Moore JH, Karagas MR. Drinking-water arsenic exposure modulates gene expression in human lymphocytes from a U.S. population. Environ Health Perspect. 2008 Apr;116(4):524-31. (view details on MedLine)

  • Andrew AS, Mason RA, Kelsey KT, Schned AR, Marsit CJ, Nelson HH, Karagas MR. DNA repair genotype interacts with arsenic exposure to increase bladder cancer risk. Toxicol Lett. 2009 May 22;187(1):10-4. Epub 2009 Jan 20. (view details on MedLine)

  • Andrew AS, Mason RA, Memoli V, Duell EJ. Arsenic activates EGFR pathway signaling in the lung. Toxicol Sci. 2009 Jun;109(2):350-7. Epub 2009 Jan 23. (view details on MedLine)

  • Andrew AS, Gui J, Sanderson AC, Mason RA, Morlock EV, Schned AR, Kelsey KT, Marsit CJ, Moore JH, Karagas MR. Bladder cancer SNP panel predicts susceptibility and survival. Hum Genet. 2009 Jun;125(5-6):527-39. Epub 2009 Mar 1. (view details on MedLine)

  • Mason RA, Morlock EV, Karagas MR, Kelsey KT, Marsit CJ, Schned AR, Andrew AS. EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis. Carcinogenesis. 2009 Jul;30(7):1155-60. Epub 2009 Apr 16. (view details on MedLine)

  • Kwong RC, Karagas MR, Kelsey KT, Mason RA, Tanyos SA, Schned AR, Marsit CJ, Andrew AS. Arsenic exposure predicts bladder cancer survival in a US population. World J Urol. 2010 Aug;28(4):487-92. Epub 2009 Oct 16. (view details on MedLine)