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Tor D Tosteson, Sc.D.

Professor of Community and Family Medicine
Professor of The Dartmouth Institute

Community and Family Medicine
The Dartmouth Institute

Biostatistics, Harvard University, SCD 1987
Biostatistics, Harvard University, MS 1980
Economics, U. North Carolina - Chapel Hill, BA 1975

Norris Cotton Cancer Center
The Dartmouth Institute for Health Policy and Clinical Practice


Contact Information:

Dartmouth Medical School
HB 7927
Hanover NH 03755

Office: Rubin 7927
Phone: 603-653-3677
Fax: 603-653-9094
Email: tor.tosteson@dartmouth.edu

Professional Interests:

My current research interests revolve around challenging methodological and statistical problems in medicine. Applied projects include the Center for Comparative Effectiveness Research in Advanced Imaging in Cancer, the Alternative Breast Cancer Imaging Program, and the Spine Patients Outcomes Research Trial, a multicenter trial of surgery versus nonoperative methods of treating low back pain. I conduct related statistical research in the areas of covariate measurement error for nonlinear regression models and statistical methods for comparative effectiveness research.

Grant Information:

NCCC Core Grant; Center for Advanced Imaging in Cancer; Alternative Breast Imaging Program Project; QBS Post-Doctoral Training Grant; Spine Patients Outcomes Trial;

Courses Taught:

QBS Fundamentals of Biostatistics I & II; DMS Biostatistics&Epidemiology; ECS 290 CECS Doctoral Seminars;

Selected Publications:


Li Z, Tosteson TD, Bakitas MA
Joint modeling quality of life and survival using a terminal decline model in palliative care studies.
Stat Med 2013 Apr 15; 32(8):1394-406
PMID: 23001893

Sitlani CM, Heagerty PJ, Blood EA, Tosteson TD
Longitudinal structural mixed models for the analysis of surgical trials with noncompliance.
Stat Med 2012 Jul 20; 31(16):1738-60
PMID: 22344923

Bakitas M, Lyons KD, Hegel MT, Balan S, Brokaw FC, Seville J, Hull JG, Li Z, Tosteson TD, Byock IR, Ahles TA
Effects of a palliative care intervention on clinical outcomes in patients with advanced cancer: the Project ENABLE II randomized controlled trial.
JAMA 2009 Aug 19; 302(7):741-9
PMID: 19690306

Weinstein JN, Tosteson TD, Lurie JD, Tosteson AN, Blood E, Hanscom B, Herkowitz H, Cammisa F, Albert T, Boden SD, Hilibrand A, Goldberg H, Berven S, An H
Surgical versus nonsurgical therapy for lumbar spinal stenosis.
N Engl J Med 2008 Feb 21; 358(8):794-810
PMID: 18287602

Weinstein JN, Lurie JD, Tosteson TD, Hanscom B, Tosteson AN, Blood EA, Birkmeyer NJ, Hilibrand AS, Herkowitz H, Cammisa FP, Albert TJ, Emery SE, Lenke LG, Abdu WA, Longley M, Errico TJ, Hu SS
Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis.
N Engl J Med 2007 May 31; 356(22):2257-70
PMID: 17538085

Weinstein JN, Lurie JD, Tosteson TD, Skinner JS, Hanscom B, Tosteson AN, Herkowitz H, Fischgrund J, Cammisa FP, Albert T, Deyo RA
Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort.
JAMA 2006 Nov 22; 296(20):2451-9
PMID: 17119141

Weinstein JN, Tosteson TD, Lurie JD, Tosteson AN, Hanscom B, Skinner JS, Abdu WA, Hilibrand AS, Boden SD, Deyo RA
Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial.
JAMA 2006 Nov 22; 296(20):2441-50
PMID: 17119140

Tosteson TD, Buzas JS, Demidenko E, Karagas M
Power and sample size calculations for generalized regression models with covariate measurement error.
Stat Med 2003 Apr 15; 22(7):1069-82
PMID: 12652554

Tosteson TD, Buonaccorsi JP, Demidenko E
Covariate measurement error and the estimation of random effect parameters in a mixed model for longitudinal data.
Stat Med 1998 Sep 15; 17(17):1959-71
PMID: 9777689

Greenberg ER, Baron JA, Tosteson TD, Freeman DH Jr, Beck GJ, Bond JH, Colacchio TA, Coller JA, Frankl HD, Haile RW
A clinical trial of antioxidant vitamins to prevent colorectal adenoma. Polyp Prevention Study Group.
N Engl J Med 1994 Jul 21; 331(3):141-7
PMID: 8008027