Anne G Hoen
Assistant Professor of Epidemiology
Assistant Professor of Biomedical Data Science
Assistant Professor of Microbiology and Immunology
Biomedical Data Science
Microbiology and Immunology
Program in Experimental and Molecular Medicine
Quantitative Biomedical Sciences
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756
Office: Rubin 888
Dr. Hoen's research focus is on the development of the microbiome in infants and children, and the associations between environmental and dietary exposures, the microbiome, and risk for infectious and other diseases. She has a broad interest in the predictors of disease risk and microbial colonization dynamics in human populations and the environment as reflected in microbial genetic sequence variation and health informatics streams over space and time. Interdisciplinary approaches used in her research include spatial and time-series statistics, population genetics and novel disease surveillance methodologies along with tools from the fields of microbial ecology, molecular epidemiology and landscape epidemiology.
Rotations and Thesis Projects:
Development of network-based methods to capture the evolving interactions between the microorganisms that form the intestinal microbiome in infants and young children
Environmental drivers of infant intestinal microbiome development
Associations between patterns of infant intestinal microbiome establishment and health outcomes in children
Role of the intestinal and airway microbiomes in the clinical progression of cystic fibrosis
K01LM011985: Bioinformatics strategies for early life microbiomics
QBS 136 Applied Epidemiologic Methods
Dr. Hoen completed her PhD in epidemiology and public health at Yale University and received post-doctoral training at Children's Hospital Boston, Harvard Medical School and McGill University. She has broad training in biostatistics, epidemiology and public health with research experience in the evaluation of interventions, understanding infectious disease emergence and spread, and evaluating associations between the microbiome and human health. Her research uses advanced spatial and time series analysis as well as informatics and complex systems approaches. Past studies include modeling the timing and spread of influenza to estimate the effects of interventions targeting children, modeling the evolutionary ecology of the Lyme disease agent, Borrelia burgdorferi and characterizing the initial development of the human micrbiome in early life and its associations with common exposures and infectious outcomes.
Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants.
Correlates of Immunity to Influenza as Determined by Challenge of Children with Live, Attenuated Influenza Vaccine.
Prospective Study of Human Polyomaviruses and Risk of Cutaneous Squamous Cell Carcinoma in the United States.
Human polyomaviruses and incidence of cutaneous squamous cell carcinoma in the New Hampshire skin cancer study.
Association of Cesarean Delivery and Formula Supplementation With the Intestinal Microbiome of 6-Week-Old Infants.
Seroepidemiology of Human Polyomaviruses in a US Population.
Epidemic Wave Dynamics Attributable to Urban Community Structure: A Theoretical Characterization of Disease Transmission in a Large Network.
Whole genome capture of vector-borne pathogens from mixed DNA samples: a case study of Borrelia burgdorferi.
Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis.
Fetal exposures and perinatal influences on the stool microbiota of premature infants.