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Kimberley S Samkoe, PhD

Assistant Professor of Surgery
Adjunct Assistant Professor at Thayer School of Engineering


Ph.D. - 2007 - Biophysical Chemistry, University of Calgary, Calgary, AB, Canada
B.Sc.Hons. - 2001 - Biochemsitry, University of Regina, Regina, SK, Canada

Norris Cotton Cancer Center


Contact Information:

536E Borwell
One Medical Center Drive
Dartmouth Hitchcock Memorial Center
Lebanon NH 03756

Office: 536E Borwell
Phone: 603-650-7618
Email: Kimberley.S.Samkoe@Dartmouth.edu

Selected Publications:


Toxicity and Pharmacokinetic Profile for Single-Dose Injection of ABY-029: a Fluorescent Anti-EGFR Synthetic Affibody Molecule for Human Use.
Samkoe KS, Gunn JR, Marra K, Hull SM, Moodie KL, Feldwisch J, Strong TV, Draney DR, Hoopes PJ, Roberts DW, Paulsen K, Pogue BW
Mol Imaging Biol. 2017 Aug;19(4):512-521. doi: 10.1007/s11307-016-1033-y.
PMID: 27909986

Simultaneous <i>In Vivo</i> Fluorescent Markers for Perfusion, Protoporphyrin Metabolism, and EGFR Expression for Optically Guided Identification of Orthotopic Glioma.
Elliott JT, Marra K, Evans LT, Davis SC, Samkoe KS, Feldwisch J, Paulsen KD, Roberts DW, Pogue BW
Clin Cancer Res. 2017 May 1;23(9):2203-2212. doi: 10.1158/1078-0432.CCR-16-1400. Epub 2016 Oct 31.
PMID: 27799250

Optical tracer size differences allow quantitation of active pumping rate versus Stokes-Einstein diffusion in lymphatic transport.
DSouza AV, Marra K, Gunn JR, Samkoe KS, Pogue BW
J Biomed Opt. 2016 Oct 1;21(10):100501. doi: 10.1117/1.JBO.21.10.100501.
PMID: 27752703

Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
de Souza AL, Marra K, Gunn J, Samkoe KS, Kanick SC, Davis SC, Chapman MS, Maytin EV, Hasan T, Pogue BW
Br J Cancer. 2016 Sep 27;115(7):805-13. doi: 10.1038/bjc.2016.267. Epub 2016 Aug 30.
PMID: 27575852

Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging.
DSouza AV, Lin H, Henderson ER, Samkoe KS, Pogue BW
J Biomed Opt. 2016 Aug 1;21(8):80901. doi: 10.1117/1.JBO.21.8.080901.
PMID: 27533438

Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions.
de Souza AL, Marra K, Gunn J, Samkoe KS, Hoopes PJ, Feldwisch J, Paulsen KD, Pogue BW
Mol Imaging Biol. 2017 Feb;19(1):41-48. doi: 10.1007/s11307-016-0980-7.
PMID: 27379987

Vision 20/20: Molecular-guided surgical oncology based upon tumor metabolism or immunologic phenotype: Technological pathways for point of care imaging and intervention.
Pogue BW, Paulsen KD, Samkoe KS, Elliott JT, Hasan T, Strong TV, Draney DR, Feldwisch J
Med Phys. 2016 Jun;43(6):3143-3156. doi: 10.1118/1.4951732.
PMID: 27277060

Revisiting photodynamic therapy dosimetry: reductionist &amp; surrogate approaches to facilitate clinical success.
Pogue BW, Elliott JT, Kanick SC, Davis SC, Samkoe KS, Maytin EV, Pereira SP, Hasan T
Phys Med Biol. 2016 Apr 7;61(7):R57-89. doi: 10.1088/0031-9155/61/7/R57. Epub 2016 Mar 10.
PMID: 26961864

Image-derived arterial input function for quantitative fluorescence imaging of receptor-drug binding in vivo.
Elliott JT, Samkoe KS, Davis SC, Gunn JR, Paulsen KD, Roberts DW, Pogue BW
J Biophotonics. 2016 Mar;9(3):282-95. doi: 10.1002/jbio.201500162. Epub 2015 Sep 9.
PMID: 26349671

Advancing Molecular-Guided Surgery through probe development and testing in a moderate cost evaluation pipeline.
Pogue BW, Paulsen KD, Hull SM, Samkoe KS, Gunn J, Hoopes J, Roberts DW, Strong TV, Draney D, Feldwisch J
Proc SPIE Int Soc Opt Eng. 2015 Mar 4;9311 pii: 931112.
PMID: 25914500