Publications (10 Most Recent)

Characterizing the Pathogenic, Genomic, and Chemical Traits of <i>Aspergillus fischeri</i>, a Close Relative of the Major Human Fungal Pathogen <i>Aspergillus fumigatus</i>.
Mead ME, Knowles SL, Raja HA, Beattie SR, Kowalski CH, Steenwyk JL, Silva LP, Chiaratto J, Ries LNA, Goldman GH, Cramer RA, Oberlies NH, Rokas A
mSphere. 2019 Feb 20;4(1) pii: e00018-19. doi: 10.1128/mSphere.00018-19. Epub 2019 Feb 20.
PMID: 30787113

Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in <i>Aspergillus fumigatus</i>.
de Assis LJ, Manfiolli A, Mattos E, Fabri JHTM, Malavazi I, Jacobsen ID, Brock M, Cramer RA, Thammahong A, Hagiwara D, Ries LNA, Goldman GH
MBio. 2018 Dec 11;9(6) pii: e01952-18. doi: 10.1128/mBio.01952-18. Epub 2018 Dec 11.
PMID: 30538182

Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung.
Alexander MP, Fiering SN, Ostroff GR, Cramer RA, Mullins DW
Cancer Immunol Immunother. 2018 Nov;67(11):1731-1742. doi: 10.1007/s00262-018-2234-9. Epub 2018 Aug 23.
PMID: 30167860

Response to Comment on "Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death".
Shlezinger N, Irmer H, Dhingra S, Beattie SR, Cramer RA, Braus GH, Sharon A, Hohl TM
Science. 2018 Jun 22;360(6395) pii: eaas9457. doi: 10.1126/science.aas9457.
PMID: 29930111

Host-Derived Leukotriene B<sub>4</sub> Is Critical for Resistance against Invasive Pulmonary Aspergillosis.
Caffrey-Carr AK, Hilmer KM, Kowalski CH, Shepardson KM, Temple RM, Cramer RA, Obar JJ
Front Immunol. 2017;8:1984. doi: 10.3389/fimmu.2017.01984. Epub 2018 Jan 11.
PMID: 29375586

Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses.
Boutens L, Hooiveld GJ, Dhingra S, Cramer RA, Netea MG, Stienstra R
Diabetologia. 2018 Apr;61(4):942-953. doi: 10.1007/s00125-017-4526-6. Epub 2018 Jan 14.
PMID: 29333574

Hyperbaric Oxygen Reduces Aspergillus fumigatus Proliferation <i>In Vitro</i> and Influences <i>In Vivo</i> Disease Outcomes.
Dhingra S, Buckey JC, Cramer RA
Antimicrob Agents Chemother. 2018 Mar;62(3) pii: e01953-17. doi: 10.1128/AAC.01953-17. Epub 2018 Feb 23.
PMID: 29229641

Modulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis.
Kale SD, Ayubi T, Chung D, Tubau-Juni N, Leber A, Dang HX, Karyala S, Hontecillas R, Lawrence CB, Cramer RA, Bassaganya-Riera J
Sci Rep. 2017 Dec 6;7(1):17096. doi: 10.1038/s41598-017-17000-1. Epub 2017 Dec 6.
PMID: 29213115

Overview of carbon and nitrogen catabolite metabolism in the virulence of human pathogenic fungi.
Ries LNA, Beattie S, Cramer RA, Goldman GH
Mol Microbiol. 2018 Feb;107(3):277-297. doi: 10.1111/mmi.13887. Epub 2017 Dec 29.
PMID: 29197127

IL-1α is Critical for Resistance Against Highly Virulent <i>Aspergillus fumigatus</i> Isolates.
Caffrey-Carr AK, Kowalski CH, Beattie SR, Blaseg NA, Upshaw CR, Thammahong A, Lust HE, Tang YW, Hohl TM, Cramer RA, Obar JJ
Infect Immun. 2017 Sep 25; pii: IAI.00661-17. doi: 10.1128/IAI.00661-17. Epub 2017 Sep 25.
PMID: 28947643