Publications (10 Most Recent)

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus.
Thammahong A, Dhingra S, Bultman KM, Kerkaert JD, Cramer RA
mSphere. 2019 May 8;4(3) pii: e00244-19. doi: 10.1128/mSphere.00244-19. Epub 2019 May 8.
PMID: 31068436

Natamycin and Voriconazole Exhibit Synergistic Interactions with Nonantifungal Ophthalmic Agents against Fusarium Species Ocular Isolates.
Rees CA, Bao R, Zegans ME, Cramer RA
Antimicrob Agents Chemother. 2019 Jul;63(7) pii: e02505-18. doi: 10.1128/AAC.02505-18. Epub 2019 Jun 24.
PMID: 31010869

Characterizing the Pathogenic, Genomic, and Chemical Traits of Aspergillus fischeri, a Close Relative of the Major Human Fungal Pathogen Aspergillus fumigatus.
Mead ME, Knowles SL, Raja HA, Beattie SR, Kowalski CH, Steenwyk JL, Silva LP, Chiaratto J, Ries LNA, Goldman GH, Cramer RA, Oberlies NH, Rokas A
mSphere. 2019 Feb 20;4(1) pii: e00018-19. doi: 10.1128/mSphere.00018-19. Epub 2019 Feb 20.
PMID: 30787113

Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in Aspergillus fumigatus.
de Assis LJ, Manfiolli A, Mattos E, Fabri JHTM, Malavazi I, Jacobsen ID, Brock M, Cramer RA, Thammahong A, Hagiwara D, Ries LNA, Goldman GH
MBio. 2018 Dec 11;9(6) pii: e01952-18. doi: 10.1128/mBio.01952-18. Epub 2018 Dec 11.
PMID: 30538182

Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung.
Alexander MP, Fiering SN, Ostroff GR, Cramer RA, Mullins DW
Cancer Immunol Immunother. 2018 Nov;67(11):1731-1742. doi: 10.1007/s00262-018-2234-9. Epub 2018 Aug 23.
PMID: 30167860

Response to Comment on "Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death".
Shlezinger N, Irmer H, Dhingra S, Beattie SR, Cramer RA, Braus GH, Sharon A, Hohl TM
Science. 2018 Jun 22;360(6395) pii: eaas9457. doi: 10.1126/science.aas9457.
PMID: 29930111

Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis.
Caffrey-Carr AK, Hilmer KM, Kowalski CH, Shepardson KM, Temple RM, Cramer RA, Obar JJ
Front Immunol. 2017;8:1984. doi: 10.3389/fimmu.2017.01984. Epub 2018 Jan 11.
PMID: 29375586

Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses.
Boutens L, Hooiveld GJ, Dhingra S, Cramer RA, Netea MG, Stienstra R
Diabetologia. 2018 Apr;61(4):942-953. doi: 10.1007/s00125-017-4526-6. Epub 2018 Jan 14.
PMID: 29333574

Hyperbaric Oxygen Reduces Aspergillus fumigatus Proliferation In Vitro and Influences In Vivo Disease Outcomes.
Dhingra S, Buckey JC, Cramer RA
Antimicrob Agents Chemother. 2018 Mar;62(3) pii: e01953-17. doi: 10.1128/AAC.01953-17. Epub 2018 Feb 23.
PMID: 29229641

Modulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis.
Kale SD, Ayubi T, Chung D, Tubau-Juni N, Leber A, Dang HX, Karyala S, Hontecillas R, Lawrence CB, Cramer RA, Bassaganya-Riera J
Sci Rep. 2017 Dec 6;7(1):17096. doi: 10.1038/s41598-017-17000-1. Epub 2017 Dec 6.
PMID: 29213115