Publications (10 Most Recent)
Insights into Aspergillus fumigatus morphogenesis and pathogenesis through the putative lipid transporter ArvA.
Gutierrez-Perez C, Jones JT, Puerner CTS, Vellanki S, Kordana NE, James MR, Vesely EM, Johnson A, Cramer RA
bioRxiv. 2025 Dec 4; pii: 2025.12.04.692327. doi: 10.64898/2025.12.04.692327. Epub 2025 Dec 4.
PMID: 41573828
Home sputum collection for Aspergillus fumigatus detection in adults with cystic fibrosis.
Hong G, Walsh J, Koshy A, Hsu JY, O'Dea AL, Vesely EM, Memon W, Dezube RH, Goss CH, Goss LB, Greene A, Gross JE, Wilson A, Nichols DP, Zhang SX, Cramer RA
ERJ Open Res. 2025 Nov;11(6) pii: 00272-2025. doi: 10.1183/23120541.00272-2025. Epub 2025 Dec 1.
PMID: 41333983
A ceramide synthase is important for filamentous fungal biofilm morphology and antifungal drug resistance.
Puerner CTS, Wilkins OM, Cramer RA
bioRxiv. 2025 Nov 17; pii: 2025.11.16.688756. doi: 10.1101/2025.11.16.688756. Epub 2025 Nov 17.
PMID: 41332551
Transcriptional and metabolic modeling analyses of developing Aspergillus fumigatus biofilms reveal metabolic shifts required for biofilm maturation.
Puerner C, Morelli KA, Kerkaert JD, Jones JT, Quinn KG, DeMichaelis N, Vellanki S, Liao C, Cramer RA
mSphere. 2025 Dec 23;10(12):e0075225. doi: 10.1128/msphere.00752-25. Epub 2025 Nov 28.
PMID: 41314177
Transcriptional analysis of developing Aspergillus fumigatus biofilms reveals metabolic shifts required for biofilm maintenance.
Puerner C, Morelli KA, Kerkaert JD, Jones JT, Quinn KG, Vellanki S, Cramer RA
bioRxiv. 2025 Jun 2; pii: 2025.06.02.657448. doi: 10.1101/2025.06.02.657448. Epub 2025 Jun 2.
PMID: 40501668
Propranolol is efficacious against Aspergillus and Fusarium corneal isolates in vitro and in a murine model of Aspergillus keratitis.
Zegans ME, Kamath MM, Jones JT, Bao R, Ross BS, Gutierrez-Perez C, Adams EM, Lightfoot JD, Poimenidou G, Pavuluri C, Prajna V, Cramer RA, Fuller KK
Antimicrob Agents Chemother. 2025 Jun 4;69(6):e0166424. doi: 10.1128/aac.01664-24. Epub 2025 May 15.
PMID: 40372030
Giant transposons promote strain heterogeneity in a major fungal pathogen.
Gluck-Thaler E, Forsythe A, Puerner C, Gutierrez-Perez C, Stajich JE, Croll D, Cramer RA, Vogan AA
mBio. 2025 Jun 11;16(6):e0109225. doi: 10.1128/mbio.01092-25. Epub 2025 May 12.
PMID: 40353686
Targeting fungal lipid synthesis for antifungal drug development and potentiation of contemporary antifungals.
Gutierrez-Perez C, Cramer RA
NPJ Antimicrob Resist. 2025 Apr 12;3(1):27. doi: 10.1038/s44259-025-00093-4. Epub 2025 Apr 12.
PMID: 40221522
Recent developments in Aspergillus fumigatus research: diversity, drugs, and disease.
Kordana N, Johnson A, Quinn K, Obar JJ, Cramer RA
Microbiol Mol Biol Rev. 2025 Mar 27;89(1):e0001123. doi: 10.1128/mmbr.00011-23. Epub 2025 Feb 10.
PMID: 39927770
Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces Aspergillus fumigatus in Cystic Fibrosis.
Morgan SJ, Nichols DP, Ni W, Hong G, Salipante SJ, Solomon GM, Rowe SM, Clancy JP, Cramer RA, Singh PK
Am J Respir Crit Care Med. 2024 Nov 1;210(9):1155-1158. doi: 10.1164/rccm.202406-1128RL.
PMID: 39189854