Publications (10 Most Recent)
Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces Aspergillus fumigatus in Cystic Fibrosis.
Morgan SJ, Nichols DP, Ni W, Hong G, Salipante SJ, Solomon GM, Rowe SM, Clancy JP, Cramer RA, Singh PK, PROMISE-Micro Study Group
Am J Respir Crit Care Med. 2024 Aug 27; doi: 10.1164/rccm.202406-1128RL. Epub 2024 Aug 27.
PMID: 39189854
New developments in Aspergillus fumigatus and host reactive oxygen species responses.
James MR, Doss KE, Cramer RA
Curr Opin Microbiol. 2024 Aug;80:102521. doi: 10.1016/j.mib.2024.102521. Epub 2024 Jul 29.
PMID: 39079399
Giant transposons promote strain heterogeneity in a major fungal pathogen.
Gluck-Thaler E, Forsythe A, Puerner C, Stajich JE, Croll D, Cramer RA, Vogan AA
bioRxiv. 2024 Jun 28; pii: 2024.06.28.601215. doi: 10.1101/2024.06.28.601215. Epub 2024 Jun 28.
PMID: 38979181
Unsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen Aspergillus fumigatus.
Gutierrez-Perez C, Puerner C, Jones JT, Vellanki S, Vesely EM, Xatse MA, Viera AFC, Olsen CP, Attiku KO, Cardinale S, Kwasny SM, G-Dayanandan N, Opperman TJ, Cramer RA
mBio. 2024 Jul 17;15(7):e0116624. doi: 10.1128/mbio.01166-24. Epub 2024 Jun 27.
PMID: 38934618
BTK drives neutrophil activation for sterilizing antifungal immunity.
Desai JV, Zarakas MA, Wishart AL, Roschewski M, Aufiero MA, Donko Á, Wigerblad G, Shlezinger N, Plate M, James MR, Lim JK, Uzel G, Bergerson JR, Fuss I, Cramer RA, Franco LM, Clark ES, Khan WN, Yamanaka D, Chamilos G, El-Benna J, Kaplan MJ, Staudt LM, Leto TL, Holland SM, Wilson WH, Hohl TM, Lionakis MS
J Clin Invest. 2024 May 2;134(12) doi: 10.1172/JCI176142. Epub 2024 May 2.
PMID: 38696257
Intestinal Bacteroides modulates inflammation, systemic cytokines, and microbial ecology via propionate in a mouse model of cystic fibrosis.
Price CE, Valls RA, Ramsey AR, Loeven NA, Jones JT, Barrack KE, Schwartzman JD, Royce DB, Cramer RA, Madan JC, Ross BD, Bliska J, O'Toole GA
mBio. 2024 Feb 14;15(2):e0314423. doi: 10.1128/mbio.03144-23. Epub 2024 Jan 5.
PMID: 38179971
The cystic fibrosis treatment Trikafta affects the growth, viability, and cell wall of Aspergillus fumigatus biofilms.
Jones JT, Morelli KA, Vesely EM, Puerner CTS, Pavuluri CK, Ross BS, van Rhijn N, Bromley MJ, Cramer RA
mBio. 2023 Oct 31;14(5):e0151623. doi: 10.1128/mbio.01516-23. Epub 2023 Oct 13.
PMID: 37830825
Aspergillus fumigatus cytochrome c impacts conidial survival during sterilizing immunity.
James MR, Aufiero MA, Vesely EM, Dhingra S, Liu K-W, Hohl TM, Cramer RA
mSphere. 2023 Dec 20;8(6):e0030523. doi: 10.1128/msphere.00305-23. Epub 2023 Oct 12.
PMID: 37823656
Recent Advances in Understanding the Human Fungal Pathogen Hypoxia Response in Disease Progression.
Puerner C, Vellanki S, Strauch JL, Cramer RA
Annu Rev Microbiol. 2023 Sep 15;77:403-425. doi: 10.1146/annurev-micro-032521-021745.
PMID: 37713457
Aspergillus fumigatus cytochrome c impacts conidial survival during sterilizing immunity.
James MR, Aufiero MA, Vesely EM, Dhingra S, Liu KW, Hohl TM, Cramer RA
bioRxiv. 2023 Jun 7; pii: 2023.06.07.544103. doi: 10.1101/2023.06.07.544103. Epub 2023 Jun 7.
PMID: 37333187