Recent student publications


Michael B. Miller, Daphne W. Wang, Fei Wang, Geoffrey P. Noble, Jiyan Ma, Virgil L. Woods, Jr., Sheng Li, and Surachai Supattapone. "Cofactor Molecules Induce Structural Transformation During Infectious Prion Formation" Structure. 2013. In press.

Audu CO, Cochran JC, Pellegrini M, Mierke DF. "Recombinant production of TEV cleaved human parathyroid hormone" J Pept Sci. 2013 Aug;19(8):504-10. doi: 10.1002/psc.2528. Epub 2013 Jun 23.

Cook, J. B., Dumitru, A. M. G., O'Buckley, T. K. and Morrow, A. L. (2013), Ethanol Administration Produces Divergent Changes in GABAergic Neuroactive Steroid Immunohistochemistry in the Rat Brain. Alcoholism: Clinical and Experimental Research. doi: 10.1111/acer.12223

Hahn, CK and Lowrey, CH. Eukaryotic Initiation Factor 2 αλπηα Phosphorylation Mediates Fetal Hemoglobin Induction through a Post-Transcriptional Mechanism. Blood, 122 (4): 477-485 (2013)

Bekelis K (co-first author), Bakhoum SF (co-first author), Desai A, Mackenzie TA, Roberts DW, "Outcome prediction in intracranial tumor surgery: the National Surgical Quality Improvement Program 2005-2010" J Neurooncol. 2013 Feb 24. [Epub ahead of print], PMID: 23436132

Bekelis K (co-first author), Bakhoum SF (co-first author), Desai A, Mackenzie TA, Goodney P, Labropoulos N. "A Risk Factor-based Predictive Model of Outcomes in Carotid Endarterectomy: The National Surgical Quality Improvement Program 2005-2010" Stroke. 2013 Feb 14. [Epub ahead of print] PMID: 23412374

Ran C, Liu H, Hitoshi Y, Israel M. "Proliferation-independent control of tumor glycolysis by PDGFR-mediated AKT activation" Cancer Res. 2013 Jan 15. [Epub ahead of print] PMID: 23322009

Sexton K, Davis S, McClatchy B, Valdes PA, Kanick SC, Paulsen KD, Roberts DW, Pogue BW. Pulsed light imaging for fluorescence guided surgery under normal room lighting. (Opt Lett. 2013 Sep 1;38(17):3249-52).PMID: Pending EDIT FOR ERAS

Valdes PA, Jacobs VL, Wilson BC, Leblond F, Roberts DW, Paulsen KD. System and methods for wide-field quantitative fluorescence imaging during neurosurgery. (Opt Lett. 2013 Aug 1;38(15):2786-8). PMID: 23903142

Valdes PA, Bekelis K, Harris BT, Wilson BC, Leblond F, Kim A, Erkmen K, Paulsen KD, Roberts DW. 5-aminolevulinic acid-induced protoporphyrin IX fluorescence guided surgery in meningiomas: qualitative and quantitative measurements in vivo. (Neurosurgery 2013 Jul 24 [Epub ahead of print]). PMID: 23887194

A. Petryk, A. J. Giustini, R. E. Gottesman, P. A. Kaufman, P. J. Hoopes. "Magnetic nanoparticle hyperthermia enhancement of cisplatinum chemotherapy cancer treatment." International Journal of Hyperthermia (2013). Accepted

J. Pearce, A. J. Giustini, R. S. Stigliano, P. Jack Hoopes. "Magnetic Heating of Nanoparticles: The Importance of Particle Clustering to Achieve Therapeutic Temperatures" Journal of Nanotechnology in Engineering and Medicine (2013). 4(1), 110071-1100714. PMID: 23919112

M. A. Crane-Godreau, C. C. Black, A. J. Giustini, T. Dechen, J. Ryu, J. A. Jukosky, H.-K. Lee, K. Bessette, N. R. Ratcliffe, P. J. Hoopes, S. Fiering, J. A. Kelly, J. C. Leiter. "Modeling the influence of vitamin D deficiency on cigarette smoke-induced emphysema." Frontiers in Physiology (2013). 4, 132.

Rasapalli S, Fan Y, Yu M, Rees C, Harris JT, Golen JA, Jasinski JP, Rheingold AL, Kwasny SM, Opperman TJ. "Detour of prenostodione synthesis towards pyrazolones for antibacterial activity." Bioorganic & Medicinal Chemistry Letters, Volume 23, Issue 11, 1 June 2013, Pages 3235-3238


Supattapone S and MB Miller, "Cofactor Involvement in Prion Propagation". In W-Q Zou and P Gambetti [Ed.] Prions and Diseases: Physiology and Pathophysiology [vol. 1]. Springer, 2012.

Turnbaugh JA, U Unterberger, P Saá, T Massignan, B Fluharty, I Solomon, MB Miller, S Supattapone, E Biasini, and DA Harris, "The N-Terminal, Polybasic Region of PrPC Dictates the Efficiency of Prion Propagation by Binding to PrPSc" Journal of Neuroscience, 2012; 32(26):8817-8830.

Audu CO, O'Hara B, Pellegrini M, Wang L, Atwood WJ, Mierke DF. "Reining in Polyoma Virus Associated Nephropathy: Design and Characterization of a Template Mimicking BK Viral Coat Protein Cellular Binding" Biochemistry 2012; 51 (41), 8092-8099.

Valdés PA, Moses ZM, Kim A, Paulsen KD, Wilson BC, Roberts DW, Harris BT. Relationship between ex vivo gadolinium concentrations and 5-aminolevulinic acid-induced protoporphyrin IX levels in gliomas: a quantitative study on a relationship between protoporphyrin IX levels and blood-brain barrier breakdown. (J Neuropathol Exp Neurol. 2012 Aug 8 [Epub ahead of print]).

Roberts DW, Valdés PA, Harris BT, Hartov A, Fan X, Songbai J, Pogue BW, Lebnlond F, Tosteson TD, Wilson BC, Paulsen KD. Glioblastoma Multiforme Treatment with Clinical Trials for Surgical Resection (Aminolevulinic Acid). (Neurosurg Clin N Am, 2012 Jul;23(3):371-7).

Valdés PA, Leblond F, Kim A, Paulsen KD, Wilson BC, Roberts DW. A spectrally-constrained dual-band normalization technique for protoporphyrin IX quantification in fluorescence guided surgery. (Opt Lett. 2012 Jun 1;37(11):1817-9).

Jacobs VL, Liu Y, De Leo JA. Propentofylline targets TROY, a novel microglial signaling pathway. PLoS One. 2012;7(5):e37955. Epub 2012 May 23. PMID: 22649568

Konecky SD, Owen CM, Rice T, Valdés PA, Kolste K, Wilson BC, Leblond F, Roberts DW, Paulsen KD, Tromberg BJ. Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models. (J Biomed Opt. 2012 May;17(5):0506008).

Landry RP, Jacobs VL, Romero-Sandoval EA, DeLeo JA. Propentofylline, a CNS glial modulator does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages. Exp Neurol. 2012 Apr;234(2):340-50. Epub 2011 Nov 15. Review. PMID: 22119425

Bakhoum SF, Compton DA. Chromosomal instability and cancer: a complex relationship with therapeutic potential. J Clin Invest. 2012 Apr 2;122(4):1138-43. doi: 10.1172/JCI59954. Epub 2012 Apr 2.

Bakhoum SF, Compton DA. Kinetochores and disease: keeping microtubule dynamics in check! Curr Opin Cell Biol. 2012 Feb;24(1):64-70. Epub 2011 Dec 21.

Walsh DJ, Noble GP, Piro JR, Supattapone S. Non-reducing alkaline solubilization and rapid on-column refolding of recombinant prion protein. Prep Biochem Biotechnol. 2012 Jan; 42(1):77-86. PubMed PMID: 22239709.

Bakhoum SF, Compton DA. Chromosomal instability and cancer: a complex relationship with therapeutic potential. The Journal of Clinical Investigation. Accepted, in press.

Valdés PA, Leblond F, Jacobs VL, Paulsen KD, Roberts DW. In vivo fluorescence detection in surgery: A review of principles, methods, and applications. (Current Medical Imaging Reviews, In Press, 2012).

Valdes PA, Leblond F, Jacobs VL, Wilson BC, Paulsen KD, Roberts DW. Quantitative, spectrally-resolved intraoperative fluorescence imaging. (Sci Rep. 2012;2:798. doi: 10.1038/srep00798. Epub 2012 Nov 12). PMID: 23152935

A. J. Giustini, I. Perreard, A. M. Rauwerdink, J. B. Weaver , P. J. Hoopes. "Noninvasive assessment of magnetic nanoparticle-cancer cell interactions." Integrative Biology (2012), 4, 1283–1288.

A. J. Giustini, A. A. Petryk, P. J. Hoopes. "Ionizing radiation increases systemic nanoparticle tumor accumulation" Nanomedicine: Nanotechnology, Biology, and Medicine (2012), 8(6), 818–821.

Bender AC, Natola H, Ndong C, Holmes GL, Scott RC, Lenck-Santini PP. Focal Scn1a knockdown induces cognitive impairment without seizures. Neurobiol Dis. 2013 Jun;54:297-307. doi: 10.1016/j.nbd.2012.12.021. Epub 2013 Jan 11. PubMed PMID: 23318929; PubMed Central PMCID: PMC3628954.


Bakhoum SF, Danilova OV, Kaur P, Levy NB, Compton DA. Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma. Clin Cancer Res. 2011 Dec 15;17(24):7704-11.

Belden CJ, Valdés PA, Ran C, Pastel DA, Harris BT, Fadul CE, Israel MA, Paulsen KD, Roberts DW. Genetics of glioblastoma: A window into its imaging and histopathologic variability. (Radiographics, 2011 Oct 31: 1717-1740). Invited Review. PMID: 21997991

Leblond F, Ovanesyan Z, Davis SC, Valdés PA, Kim A, Wilson BC, Hartov A, Pogue BW, Paulsen KD, Roberts DW. Analytic expression of fluorescence ratio detection correlates with depth in multi-spectral sub surface imaging. (Phys Med Biol, 2011 Oct 5; 56(21): 6823-6837). Review. PMID: 21971201

Valdés PA, Kim A, Leblond F, Conde OM, Harris BT, Paulsen KD, Wilson BC, Roberts DW. Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery. J Biomed Opt. 2011 Nov;16(11):116007.

Jacobs VL, Landry RP, Liu Y, Romero-Sandoval EA, De Leo JA. Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia. Neuro Oncol. 2011 Nov 15. [Epub ahead of print]

Bender AC, Morse RP, Scott RC, Holmes GL, Lenck-Santini PP. SCN1A mutations in Dravet syndrome: Impact of interneuron dysfunction on neural networks and cognitive outcome. Epilepsy Behav. Accepted 2011 Nov 27.

Holmes GL, Bender AC, Wu EX, Scott RC, Lenck-Santini PP, Morse RP. Maturation of EEG oscillations in children with sodium channel mutations. Brain Dev. 2011 Sep 20.

Kleen JK, Wu EX, Holmes GL, Scott RC, Lenck-Santini PP. Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures. J Neurosci. 2011 Oct 26;31(43):15397-406.

Kleen JK, Sesqué A, Wu EX, Miller FA, Hernan AE, Holmes GL, Scott RC. Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex. Epilepsy Behav. 2011 Oct;22(2):214-9.

Wood M, Rawe M, Johansson G, Pang S, Soderquist RS, Patel AV, Nelson S, Seibel W, Ratner N, Sanchez Y. Discovery of a Small Molecule Targeting IRA2 Deletion in Budding Yeast and Neurofibromin Loss in Malignant Peripheral Nerve Sheath Tumor Cells Mol. Cancer Ther. 2011 Sep;10(9):1740-50. Epub 2011 Jun 22

Jacobs VL, Valdés PA, Hickey WF, De Leo JA. Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumor model. ASN Neuro, 2011 Aug 3;3(3).

Pablo A. Valdés, Anthony Kim, Marco Brantsch, Carolyn Niu, Ziev B. Moses, Tor D. Tosteson, Brian C. Wilson, Keith D. Paulsen, David W. Roberts, and Brent T. Harris. δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy. Neuro Oncol (2011) 13(8): 846-856 doi:10.1093/neuonc/nor086.

Isaev D, Zhao Q, Kleen JK, Lenck-Santini PP, Adstamongkonkul D, Isaeva E, Holmes GL. Neuroaminidase reduces interictal spikes in a rat temporal lobe epilepsy model. Epilepsia. 2011 Mar;52(3):e12-5. doi:10.1111/j.1528-1167.2011.02988.x. Epub 2011 Mar 2. PubMed PMID: 21366554.

Megli CJ, Yuen AS, Kolappan S, Richardson MR, Dharmasena MN, Krebs SJ, Taylor RK, Craig L. Crystal structure of the Vibrio cholerae colonization factor TcpF and identification of a functional immunogenic site. J Mol Biol. 2011 Mar 24. [Epub ahead of print] PubMed PMID: 21440558.

Miller MB, Supattapone S. Superparamagnetic nanoparticle capture of prions for amplification. J Virol. 2011 Mar;85(6):2813-7. Epub 2011 Jan 12. PubMed PMID: 21228242.

Bekelis K, Valdes PA, Erkmen K, Leblond F, Kim A, Wilson BC, Harris BT, Paulsen KD, Roberts DW. Quantitative and qualitative ALA-induced PpIX fluorescence in skull base meningiomas. (Neurosurgical Focus, 2011 May; 30(5): E8) PMID: 21529179

Valdés PA, Leblond F, Kim A, Harris BT, Wilson BC, Fan X, Tosteson TD, Hartov A, Ji S, Paulsen KD, Roberts DW. Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as a surgical biomarker to guide resection procedures. (Journal of Neurosurgery, 2011 Mar 25. [Epub ahead of print]) PMID: 21529179

Whitson W, Valdés PA, Harris BT, Paulsen KD, Roberts DW. Confocal microscopy for the histologic fluorescence pattern of a recurrent atypical meningioma. (Neurosurgery, 2011 Mar 8. [Epub ahead of print]) PMID: 2138989

Roberts DW, Valdés PA, Harris BT, Fontaine KM, Hartov A, Fan X, Ji S, Lollis SS, Pogue BW, Leblond F, Tosteson T, Wilson BC, Paulsen KD. Co-registered Fluorescence-Enhanced Tumor Resection of Malignant Glioma: Relationships between ALA-Induced PpIX Fluorescence, MRI Enhancement and Neuropathological Parameters. (J Neurosurg, 2011 Mar; 114(3): 595-603. [Epub ahead of print, Apr 9]) PMID: 2038053

A. J. Giustini, R. Ivkov, P. J. Hoopes. "Magnetic nanoparticle biodistribution following intratumoral administration." Nanotechnology (2011) vol. 22 (34) pp. 345101


Manning AL, Bakhoum SF, Maffini S, Correia-Melo C, Maiato H, Compton DA. CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity. EMBO J. 2010 Oct 20;29(20):3531-43. Epub 2010 Sep 17. PubMed PMID: 20852589; PubMed Central PMCID: PMC2964175.

Thompson SL, Bakhoum SF, Compton DA. Mechanisms of chromosomal instability. Curr Biol. 2010 Mar 23;20(6):R285-95. Review. PubMed PMID: 20334839.

Guo Y, Dolinko AV, Chinyengetere F, Stanton B, Bomberger JM, Demidenko E, Zhou DC, Gallagher R, Ma T, Galimberti F, Liu X, Sekula D, Freemantle S, Dmitrovsky E. Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemia. Cancer Res. 2010 Dec 1;70(23):9875-85. Epub 2010 Oct 8. PubMed PMID: 20935222; PubMed Central PMCID: PMC2999664.

Elfenbein A, Simons M. Auxiliary and autonomous proteoglycan signaling networks. Methods Enzymol. 2010;480:3-31. Review. PubMed PMID: 20816202.

Rauwerdink AM, Giustini AJ, Weaver JB. Simultaneous quantification of multiple magnetic nanoparticles. Nanotechnology. 2010 Nov 12;21(45):455101. Epub 2010 Oct 14. PubMed PMID: 20947953.

Horvath RJ, Landry RP, Romero-Sandoval EA, DeLeo JA. Morphine tolerance attenuates the resolution of postoperative pain and enhances spinal microglial p38 and extracellular receptor kinase phosphorylation. Neuroscience. 2010 Aug 25;169(2):843-54. Epub 2010 May 22. PubMed PMID: 20493931; PubMed Central PMCID: PMC2904400.

Côté AL, Zhang P, O'Sullivan JA, Jacobs VL, Clemis CR, Sakaguchi S, Guevara-Patino JA, Turk MJ. Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens. J Immunol. 2011 Jan 1;186(1):275-83. Epub 2010 Nov 24. PubMed PMID: 21106849; PubMed Central PMCID: PMC3050990.

Kleen JK, Holmes GL. Taming TLR4 may ease seizures. Nat Med. 2010 Apr;16(4):369-70. PubMed PMID: 20376038.

Kleen JK, Scott RC, Holmes GL, Lenck-Santini PP. Hippocampal interictal spikes disrupt cognition in rats. Ann Neurol. 2010 Feb;67(2):250-7. PubMed PMID: 20225290; PubMed Central PMCID: PMC2926932.

Martinez RM, Megli CJ, Taylor RK. Growth and laboratory maintenance of Vibrio cholerae. Curr Protoc Microbiol. 2010 May;Chapter 6:Unit 6A.1. PubMed PMID: 20440684.

Chang TY, Chang CC, Bryleva E, Rogers MA, Murphy SR. Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease. IUBMB Life. 2010 Apr;62(4):261-7. Review. PubMed PMID: 20101629.

Murad JM, Place CS, Ran C, Hekmatyar SK, Watson NP, Kauppinen RA, Israel MA. Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice. J Biol Chem. 2010 Jul 30;285(31):24164-73. Epub 2010 May 11. PubMed PMID: 20460371; PubMed Central PMCID: PMC2911309.

Corpora T, Roudaia L, Oo ZM, Chen W, Manuylova E, Cai X, Chen MJ, Cierpicki T, Speck NA, Bushweller JH. Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activity. J Mol Biol. 2010 Sep 24;402(3):560-77. Epub 2010 Aug 11. PubMed PMID: 20708017; PubMed Central PMCID: PMC2945414.

Shindiapina P, Barlowe C. Requirements for transitional endoplasmic reticulum site structure and function in Saccharomyces cerevisiae. Mol Biol Cell. 2010 May 1;21(9):1530-45. Epub 2010 Mar 3. PubMed PMID: 20200224; PubMed Central PMCID: PMC2861612.

Pogue BW, Gibbs-Strauss S, Valdés PA, Samkoe K, Roberts, DW, Paulsen KD. Review of Neurosurgical Fluorescence Imaging Methodologies. (IEEE Journal of Selected Topics in Quantum Electronics, 2010 Jun; 16(3): 493-505). Invited Review PMID: 20671936

Valdés PA, Samkoe K, O'Hara JA, Roberts DW, Paulsen KD, Pogue BW. Deferoxamine iron chelation increases delta-aminolevulinic acid induced protoporphyrin IX in xenograft glioma model. Photochem Photobiol. 2010 Mar-Apr;86(2):471-5. Epub 2009 Dec 7. PubMed PMID: 20003159; PubMed Central PMCID: PMC2875336.

Lollis SS, Valdés PA, Li Z, Ball PA, Roberts DW. Cause-specific mortality among neurosurgeons. (J Neurosurg, 2010 Sep; 113(3): 474-478. [Epub ahead of print, Feb 19]) PMID: 20170305

Wood MD, Sanchez Y. Deregulated Ras signaling compromises DNA damage checkpoint recovery in S. cerevisiae. Cell Cycle. 2010 Aug 15;9(16):3353-63. Epub 2010 Aug 17. PubMed PMID: 20716966.

A. J. Giustini, et al. "Magnetic Nanoparticle Hyperthermia in Cancer Treatment." Nano LIFE (2010). Vol 1 (1-2) 17-32.

Rosas HD, Lee SY, Bender AC, Zaleta AK, Vangel M, Yu P, Fischl B, Pappu V,Onorato C, Cha JH, Salat DH, Hersch SM. Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage. 2010 Feb 15;49(4):2995-3004. doi: 10.1016/j.neuroimage.2009.10.015. Epub 2009 Oct 19. PubMed PMID: 19850138; PubMed Central PMCID: PMC3725957.


Kollu S, Bakhoum SF, Compton DA. Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells. Curr Biol. 2009 Dec 29;19(24):2108-13. PubMed PMID: 19931454; PubMed Central PMCID: PMC2805786.

Bakhoum SF, Genovese G, Compton DA. Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr Biol. 2009 Dec 1;19(22):1937-42. Epub 2009 Oct 29. PubMed PMID: 19879145; PubMed Central PMCID: PMC2787757.

Bakhoum SF, Compton DA. Cancer: CINful centrosomes. Curr Biol. 2009 Aug 11;19(15):R642-5. Review. PubMed PMID: 19674544.

Bakhoum SF, Thompson SL, Manning AL, Compton DA. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nat Cell Biol. 2009 Jan;11(1):27-35. Epub 2008 Dec 7. PubMed PMID: 19060894; PubMed Central PMCID: PMC2614462.

Elfenbein A, Rhodes JM, Meller J, Schwartz MA, Matsuda M, Simons M. Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. J Cell Biol. 2009 Jul 13;186(1):75-83. Epub 2009 Jul 6. PubMed PMID: 19581409; PubMed Central PMCID: PMC2712988.

Romero-Sandoval EA, Horvath R, Landry RP, DeLeo JA. Cannabinoid receptor type 2 activation induces a microglial anti-inflammatory phenotype and reduces migration via MKP induction and ERK dephosphorylation. Mol Pain. 2009 May 28;5:25. PubMed PMID: 19476641; PubMed Central PMCID: PMC2704199.

Horvath RJ, DeLeo JA. Morphine enhances microglial migration through modulation of P2X4 receptor signaling. J Neurosci. 2009 Jan 28;29(4):998-1005. PubMed PMID: 19176808; PubMed Central PMCID: PMC2727471.

Geoghegan JC, Miller MB, Kwak AH, Harris BT, Supattapone S. Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor. PLoS Pathog. 2009 Jul;5(7):e1000535. Epub 2009 Jul 31. PubMed PMID: 19649330; PubMed Central PMCID: PMC2713408.

Roudaia L, Cheney MD, Manuylova E, Chen W, Morrow M, Park S, Lee CT, Kaur P, Williams O, Bushweller JH, Speck NA. CBFbeta is critical for AML1-ETO and TEL-AML1 activity. Blood. 2009 Mar 26;113(13):3070-9. Epub 2009 Jan 29. PubMed PMID: 19179469; PubMed Central PMCID: PMC2662647.

Valdés PA, Fan X, Ji S, Harris BT, Paulsen KD, Roberts DW. Estimation of brain deformation for volumetric image updating in protoporphyrin IX fluorescence-guided resection. Stereotact Funct Neurosurg. 2010;88(1):1-10. Epub 2009 Nov 12. PubMed PMID: 19907205; PubMed Central PMCID: PMC2813794.

Leblond F, Davis SC, Valdés PA, Pogue BW. Pre-clinical Whole-Body Fluorescence Imaging: Review of Instruments, Methods, and Applications. (J Photochem Photobiol B, 2009 Nov 26. [Epub ahead of print]) Review PMID: 20031443

Yasaitis L, Fisher E, Mackenzie TA, Wasson J. Healthcare intensity is associated with lower ratings of healthcare quality by younger adults. J Ambul Care Manage. 2009 Jul-Sep;32(3):226-31. PubMed PMID: 19542812.

Yasaitis L, Fisher ES, Skinner JS, Chandra A. Hospital quality and intensity of spending: is there an association? Health Aff (Millwood). 2009 Jul-Aug;28(4):w566-72. Epub 2009 May 21. PubMed PMID: 19460774; PubMed Central PMCID: PMC2768577.


Chinyengetere F, Jamieson ER. Impact of the oxidized guanine lesion spiroiminodihydantoin on the conformation and thermodynamic stability of a 15-mer DNA duplex. Biochemistry. 2008 Feb 26;47(8):2584-91. PubMed PMID: 18281959.

Murakami M, Elfenbein A, Simons M. Non-canonical fibroblast growth factor signalling in angiogenesis. Cardiovasc Res. 2008 May 1;78(2):223-31. Epub 2007 Dec 4. Review. PubMed PMID: 18056763.

Horvath RJ, Nutile-McMenemy N, Alkaitis MS, Deleo JA. Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures. J Neurochem. 2008 Oct;107(2):557-69. Epub 2008 Sep 18. PubMed PMID: 18717813; PubMed Central PMCID: PMC2581646.

Romero-Sandoval EA, Horvath RJ, DeLeo JA. Neuroimmune interactions and pain: focus on glial-modulating targets. Curr Opin Investig Drugs. 2008 Jul;9(7):726-34. Review. PubMed PMID: 18600578; PubMed Central PMCID: PMC2696046.

Kleen JK, Holmes GL. Brain inflammation initiates seizures. Nat Med. 2008 Dec;14(12):1309-10. PubMed PMID: 19057551.

Urano Y, Watanabe H, Murphy SR, Shibuya Y, Geng Y, Peden AA, Chang CC, Chang TY. Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16513-8. Epub 2008 Oct 22. Erratum in: Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19561. PubMed PMID: 18946045; PubMed Central PMCID: PMC2575451.

Roudaia L, Speck NA. A MENage a Trois in leukemia. Cancer Cell. 2008 Jul 8;14(1):3-5. PubMed PMID: 18598937.


Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Mol Biol Cell. 2007 Aug;18(8):2970-9. Epub 2007 May 30. PubMed PMID: 17538014; PubMed Central PMCID: PMC1949365.

Tirziu D, Chorianopoulos E, Moodie KL, Palac RT, Zhuang ZW, Tjwa M, Roncal C, Eriksson U, Fu Q, Elfenbein A, Hall AE, Carmeliet P, Moons L, Simons M. Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. J Clin Invest. 2007 Nov;117(11):3188-97. PubMed PMID: 17975666; PubMed Central PMCID: PMC2045601.

Gorczynski MJ, Grembecka J, Zhou Y, Kong Y, Roudaia L, Douvas MG, Newman M, Bielnicka I, Baber G, Corpora T, Shi J, Sridharan M, Lilien R, Donald BR, Speck NA, Brown ML, Bushweller JH. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chem Biol. 2007 Oct;14(10):1186-97. PubMed PMID: 17961830.

Liu Y, Chen W, Gaudet J, Cheney MD, Roudaia L, Cierpicki T, Klet RC, Hartman K, Laue TM, Speck NA, Bushweller JH. Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity. Cancer Cell. 2007 Jun;11(6):483-97. PubMed PMID: 17560331; PubMed Central PMCID: PMC1978186.

Matheny CJ, Speck ME, Cushing PR, Zhou Y, Corpora T, Regan M, Newman M, Roudaia L, Speck CL, Gu TL, Griffey SM, Bushweller JH, Speck NA. Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles. EMBO J. 2007 Feb 21;26(4):1163-75. Epub 2007 Feb 8. PubMed PMID: 17290219; PubMed Central PMCID: PMC1852839.

Geoghegan JC, Valdés PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S. Selective incorporation of polyanionic molecules into hamster prions. (J Biol Chem, 2007 Dec 14; 282(50): 36341-53) PMID: 17949287