David J. Gladstone, ScD
Title(s)
Adjunct Professor of Medicine
Additional Titles/Positions/Affiliations
Professor of Engineering, Thayer School of Engineering at Dartmouth
Department(s)
Medicine
Education
Harvard Medical School, Post Doctoral Fellowship 1991
Massachusetts Institute of Technology Sc.D. 1989
University of Denver, B.S.Ch. 1983
Programs
Dartmouth Cancer Center
Contact Information
Dartmouth Medical School
HB 7999
Hanover NH 03755
Office: 1 Medical Center Drive
Phone: 603-640-6442
Fax: 603-650-6616
Email: david.j.gladstone@dartmouth.edu
Professional Interests
Highly conformal radiation therapy to spare normal tissues from damage secondary to treatment. Image guided radiation therapy, biological gating of therapeutic X-ray beams, image guided brachytherapy. Cherenkov emission during radiotherapy. Ultra-high dose rate radiation therapy to elicit the FLASH normal tissue sparing effect.
Grant Information
Drug-eluding Brachytherapy Implants Co-I 5% NIH/NCI R42CA224646-02
Norris Cotton Cancer Center Core Co-Director 2% NIH/NCI $3,290,263 Grant Radiation Shared Resource
5P30 CA 23108-40
Optical Cherenkov calibration for human radiation therapy Co-PI 8% NIH $423,145 R01EB023909
Electron FLASH Radiotherapy NIH U01 CA260446-01A1 Co-PI 10% $550,000/yr
Courses Taught
ENG-56, ENG-157, ENG-167, ENG-168, ENG-192
Cherenkov Imaged Bio-Morphological Features Verify Patient Positioning With Deformable Tissue Translocation in Breast Radiation Therapy. Oxygen Consumption In Vivo by Ultra-High Dose Rate Electron Irradiation Depends Upon Baseline Tissue Oxygenation. Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices. Robust Real-time Segmentation of Bio-Morphological Features in Human Cherenkov Imaging during Radiotherapy via Deep Learning. Dynamic oxygen assessment techniques enable determination of anesthesia's impact on tissue. Visual Dose Monitoring for Whole Breast Radiation Therapy Treatments via Combined Cherenkov Imaging and Scintillation Dosimetry. Commissioning an ultra-high-dose-rate electron linac with end-to-end tests. Electron beam response corrections for an ultra-high-dose-rate capable diode dosimeter. Anesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect. Technical note: Visual, rapid, scintillation point dosimetry for in vivo MV photon beam radiotherapy treatments. |
|