David J. Gladstone, ScD
Title(s):
Professor of Medicine
Additional Titles/Positions/Affiliations:
Adjunct Professor of Engineering, Thayer School of Engineering at Dartmouth
Chief of Clinical Physics, Norris Cotton Cancer Center
Department(s):
Medicine
Education:
Harvard Medical School, Post Doctoral Fellowship 1991
Massachusetts Institute of Technology Sc.D. 1989
University of Denver, B.S.Ch. 1983
Programs:
Norris Cotton Cancer Center
Contact Information:
Dartmouth Medical School
HB 7999
Hanover NH 03755
Office: 1 Medical Center Drive
Phone: 603-650-6442
Fax: 603-650-6616
Email: david.gladstone@dartmouth.edu
Assistant: Pamela Easton
Asst. Phone: 603-650-6614
Asst. Email: Pamela.L.Easton@hitchcock.org
Professional Interests:
Ultra conformal radiation therapy to spare normal tissues from damage secondary to treatment. Image guided radiation therapy, biological gating of therapeutic X-ray beams, image guided brachytherapy. Cherenkov emission during radiotherapy.
Grant Information:
Drug-eluding Brachytherapy Implants Co-I 5% NIH/NCI R42CA224646-02
Norris Cotton Cancer Center Core Co-Director 2% NIH/NCI $3,290,263 Grant Radiation Shared Resource
5P30 CA 23108-40
Optical Cherenkov calibration for human radiation therapy Co-I 8% NIH $423,145 R01EB023909
Lymph node metastases optical diagnostic and radiation therapy Co-I 5% US Army $498,530
BC150584P1
Courses Taught:
ENG-56, ENG-157, ENG-167, ENG-168, ENG-192
Selected Publications: |
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Producing a Beam Model of the Varian ProBeam Proton Therapy System using TOPAS Monte Carlo Toolkit. High Resolution pO2 Imaging Improves Quantification of the Hypoxic Fraction in Tumors during Radiotherapy. Scintillation imaging as a high-resolution, remote, versatile 2D detection system for MR-linac quality assurance. Computer animation body surface analysis of total skin electron radiation therapy dose homogeneity via Cherenkov imaging. Characterization of a new scintillation imaging system for proton pencil beam dose rate measurements. Technical Note: A novel dosimeter improves total skin electron therapy surface dosimetry workflow. Tracking tumor radiotherapy response in vivo with Cherenkov-excited luminescence ink imaging. Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy. Optical imaging method to quantify spatial dose variation due to the electron return effect in an MR-linac. Experimentally Observed Cherenkov Light Generation in the Eye During Radiation Therapy. |
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