Crystal M Noller, PhD
Title(s)
Assistant Professor of Psychiatry
Assistant Professor of Surgery
Additional Titles/Positions/Affiliations
Research Health Scientist, White River Junction VA Medical Center
Department(s)
Psychiatry
Surgery
Education
University of Miami, B.A., Psychology and Criminology, 2008
University of Miami, PhD, Health Psychology, 2014
The Miami Project to Cure Paralysis at the University of Miami Miller School of Medicine, Postdoctoral Research Fellowship, 2014-2018
Dartmouth-Hitchcock Medical Center, Postdoctoral Research Fellowship, 2018-2020
Websites
https:
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Contact Information
White River Junction VA Medical Center
215 North Main Street
Building 44, Room 2-124
White River Junction VT 05009
Phone: 802-295-9363 x 5478
Email: Crystal.M.Noller@dartmouth.edu
Professional Interests
My research is focused on understanding how dysregulation in the autonomic nervous and immune systems impedes recovery from neurotrauma and neuropsychiatric illness. I am currently evaluating the utility of neuromodulation and targeted pharmacotherapy as tools to improve functional recovery after injury, using several pre-clinical models.
Grant Information
VA Merit Award BX006246-01A2 (Holtzheimer & Noller, PI) 10/2025 – 09/2030
Targeted brain stimulation to enhance recovery after shockwave-induced blast TBI: Identifying neural biomarkers to guide treatment
VA Career Development Award-2 RX003551-01A2 (Noller, PI) 10/2022 – 09/2027
Harnessing the Cholinergic Inflammatory Reflex to Alter Neuroinflammation and Neuropsychiatric Consequences Following Traumatic Brain Injury.
Gary Tucker Junior Investigator Research Award (Noller, PI) 07/2022 – 06/2024
Neuropsychiatric consequences of brain injury: Determining how neuroinflammation may mediate neurobehavioral outcomes.
Wings for Life Spinal Cord Research Foundation (Noller, PI) 07/01/2021 – 06/30/2023
Vagus Nerve Stimulation as an Immunomodulatory Therapy for Acute Spinal Cord Injury.
VA VISN1 Career Development Award-1 2020-58 (Noller, PI) 10/1/20-9/30/22
Neuromodulation to Alter Acute Inflammation and Neuropsychiatric Deficits Following Traumatic Brain Injury.
Courses Taught
IND 103: Practical module
IND 103.5: Neuroanatomy module
Biography
Dr. Noller is a scientist with a PhD in health psychology/behavioral neuroscience. The overarching theme of her translational research involves the interrelated nature of the autonomic nervous and immune systems. Her research goals are to develop targeted therapies to address autonomic and immune dysfunction after neurotrauma and psychiatric illness in order to maximize functional recovery. Dr. Noller completed a PhD at the University of Miami, which was followed by post-doctoral training in rehabilitation and autonomic physiology at The Miami Project to Cure Paralysis, and advanced post-doctoral training in neuromodulation and neurotrauma at Dartmouth-Hitchcock Medical Center.
Glecaprevir/Pibrentasvir for Post Traumatic Stress Disorder. Psychosocial Interventions Impact on Cardiometabolic, Neurobiological, Behavioral, and Immune Outcomes in People With a Serious Mental Illness: A Systematic Review. The impact of chronic pain on brain gene expression. Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD. A multi-omic approach implicates novel protein dysregulation in post-traumatic stress disorder. Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts. Profiling neuronal methylome and hydroxymethylome of opioid use disorder in the human orbitofrontal cortex. CpH methylome analysis in human cortical neurons identifies novel gene pathways and drug targets for opioid use disorder. Vagus Nerve Stimulation in Rodent Models: An Overview of Technical Considerations. Inflammatory Stress Effects on Health and Function After Spinal Cord Injury. |
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