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Matthew J. Friedman, MD

Professor of Psychiatry
Professor of Pharmacology & Toxicology

Pharmacology & Toxicology

Dartmouth College, AB 1961
Einstein College of Medicine, PHD 1967
U. Kentucky, MD 1969

Neuroscience Center at Dartmouth


Contact Information:

Dartmouth Medical School
HB 7900
Hanover NH 03755

Office: National Center for PTSD
Phone: 802-296-5132
Fax: 802-296-5135
Email: matthew.j.friedman@dartmouth.edu

Assistant: Jan Clark
Asst. Phone: 802-296-5132
Asst. Email: jan.clark@dartmouth.edu

Professional Interests:

Dr. Matthew J. Friedman received his Ph.D. in pharmacology at the Albert Einstein College of Medicine in 1967. He then received an M.D. at the University of Kentucky, Lexington where he also had a post-doctoral fellowship, served on the faculty of the Department of Pharmacology and had a rotating internship. His residency in psychiatry was at the Massachusetts General Hospital (1970-1972) and at the Dartmouth-Hitchcock Medical Center (1972-1973). He joined the Dartmouth faculty in Psychiatry in 1973 and in Pharmacology and Toxicology in 1976. His major clinical assignment has been at the VA Medical Center, White River Junction, where he served as staff psychiatrist (1973-1978), and Chief of Psychiatry (1978-1989). He has been Executive Director of the U. S. Department of Veterans Affairs National Center for Post-Traumatic Stress Disorder (PTSD) and Professor of Psychiatry and of Pharmacology and Toxicology at Dartmouth Medical School. He has worked with PTSD patients as a clinician and researcher for thirty-five years and has published extensively on stress and PTSD, biological psychiatry, psychopharmacology, and clinical outcome studies on depression, anxiety, schizophrenia, and chemical dependency. He has over 200 publications, including seventeen books and monographs. Listed in The Best Doctors in America, he is a Distinguished Lifetime Fellow of the American Psychiatric Association, past-president of the International Society for Traumatic Stress Studies (ISTSS), Chair of the scientific advisory board of the Anxiety Disorders Association of America and has served on many VA, DoD and NIMH research, education and policy committees. He has received many honors including the ISTSS Lifetime Achievement Award in 1999.

Grant Information:

Re-Engineering Systems for Primary Care Treatment of PTSD ($1,242,100) 2007-2009. VA HSR&D. Schnurr PP & Friedman MJ, co-principal investigators

PTSD/TBI Clinical Consortium Study Site Award ($1,500,000) 2008-2013. DoD CDMRP. McAllister TW & Friedman MJ, co-principal investigators

Courses Taught:

Lecture medical students in SBM on PTSD
Teach seminars to psychiatry residents on the neurobiology and pharmacological treatment of PTSD.

Selected Publications:


VA's National PTSD Brain Bank: a National Resource for Research.
Friedman MJ, Huber BR, Brady CB, Ursano RJ, Benedek DM, Kowall NW, McKee AC, Traumatic Stress Brain Research Group.
Curr Psychiatry Rep. 2017 Aug 25;19(10):73. doi: 10.1007/s11920-017-0822-6. Epub 2017 Aug 25.
PMID: 28840457

Mobile Mindfulness Intervention on an Acute Psychiatric Unit: Feasibility and Acceptability Study.
Mistler LA, Ben-Zeev D, Carpenter-Song E, Brunette MF, Friedman MJ
JMIR Ment Health. 2017 Aug 21;4(3):e34. doi: 10.2196/mental.7717. Epub 2017 Aug 21.
PMID: 28827214

Pharmacological management of posttraumatic stress disorder.
Bernardy NC, Friedman MJ
Curr Opin Psychol. 2017 Apr;14:116-121. doi: 10.1016/j.copsyc.2017.01.003. Epub 2017 Jan 11.
PMID: 28813308

Considering future pharmacotherapy for PTSD.
Friedman MJ, Bernardy NC
Neurosci Lett. 2017 May 10;649:181-185. doi: 10.1016/j.neulet.2016.11.048. Epub 2016 Nov 24.
PMID: 27890743

Changes to the Definition of Posttraumatic Stress Disorder in the DSM-5-Reply.
Friedman MJ, Kilpatrick DG, Schnurr PP
JAMA Psychiatry. 2016 Nov 1;73(11):1203. doi: 10.1001/jamapsychiatry.2016.2401.
PMID: 27732695

Seeking the Best Bereavement-Related Diagnostic Criteria.
Friedman MJ
Am J Psychiatry. 2016 Sep 1;173(9):864-5. doi: 10.1176/appi.ajp.2016.16050580.
PMID: 27581694

How and why does the pharmaceutical management of PTSD differ between men and women?
Bernardy NC, Friedman MJ
Expert Opin Pharmacother. 2016 Aug;17(11):1449-51. doi: 10.1080/14656566.2016.1199686. Epub 2016 Jun 24.
PMID: 27276175

Correcting Misconceptions About the Diagnostic Criteria for Posttraumatic Stress Disorder in DSM-5.
Friedman MJ, Kilpatrick DG, Schnurr PP, Weathers FW
JAMA Psychiatry. 2016 Jul 1;73(7):753-4. doi: 10.1001/jamapsychiatry.2016.0745.
PMID: 27223123

The impact of proposed changes to ICD-11 on estimates of PTSD prevalence and comorbidity.
Wisco BE, Miller MW, Wolf EJ, Kilpatrick D, Resnick HS, Badour CL, Marx BP, Keane TM, Rosen RC, Friedman MJ
Psychiatry Res. 2016 Jun 30;240:226-233. doi: 10.1016/j.psychres.2016.04.043. Epub 2016 Apr 16.
PMID: 27124207

Long-Term Trajectories of PTSD in Vietnam-Era Veterans: The Course and Consequences of PTSD in Twins.
Magruder KM, Goldberg J, Forsberg CW, Friedman MJ, Litz BT, Vaccarino V, Heagerty PJ, Gleason TC, Huang GD, Smith NL
J Trauma Stress. 2016 Feb;29(1):5-16. doi: 10.1002/jts.22075. Epub 2016 Jan 13.
PMID: 26764215