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Matthew J. Friedman, MD

Emeritus Professor of Psychiatry


Dartmouth College, AB 1961
Einstein College of Medicine, PHD 1967
U. Kentucky, MD 1969

Neuroscience Center at Dartmouth


Contact Information

Dartmouth Medical School
HB 7900
Hanover NH 03755

Office: National Center for PTSD
Phone: 802-296-5132
Fax: 802-296-5135

Assistant: Jan Clark
Asst. Phone: 802-296-5132
Asst. Email:

Professional Interests

Dr. Matthew J. Friedman received his Ph.D. in pharmacology at the Albert Einstein College of Medicine in 1967. He then received an M.D. at the University of Kentucky, Lexington where he also had a post-doctoral fellowship, served on the faculty of the Department of Pharmacology and had a rotating internship. His residency in psychiatry was at the Massachusetts General Hospital (1970-1972) and at the Dartmouth-Hitchcock Medical Center (1972-1973). He joined the Dartmouth faculty in Psychiatry in 1973 and in Pharmacology and Toxicology in 1976. His major clinical assignment has been at the VA Medical Center, White River Junction, where he served as staff psychiatrist (1973-1978), and Chief of Psychiatry (1978-1989). He has been Executive Director of the U. S. Department of Veterans Affairs National Center for Post-Traumatic Stress Disorder (PTSD) and Professor of Psychiatry and of Pharmacology and Toxicology at Dartmouth Medical School. He has worked with PTSD patients as a clinician and researcher for thirty-five years and has published extensively on stress and PTSD, biological psychiatry, psychopharmacology, and clinical outcome studies on depression, anxiety, schizophrenia, and chemical dependency. He has over 200 publications, including seventeen books and monographs. Listed in The Best Doctors in America, he is a Distinguished Lifetime Fellow of the American Psychiatric Association, past-president of the International Society for Traumatic Stress Studies (ISTSS), Chair of the scientific advisory board of the Anxiety Disorders Association of America and has served on many VA, DoD and NIMH research, education and policy committees. He has received many honors including the ISTSS Lifetime Achievement Award in 1999.

Grant Information

Re-Engineering Systems for Primary Care Treatment of PTSD ($1,242,100) 2007-2009. VA HSR&D. Schnurr PP & Friedman MJ, co-principal investigators

PTSD/TBI Clinical Consortium Study Site Award ($1,500,000) 2008-2013. DoD CDMRP. McAllister TW & Friedman MJ, co-principal investigators

Courses Taught

Lecture medical students in SBM on PTSD
Teach seminars to psychiatry residents on the neurobiology and pharmacological treatment of PTSD.

Selected Publications


Prevalence of Depression and Posttraumatic Stress Disorder in Flint, Michigan, 5 Years After the Onset of the Water Crisis.
Reuben A, Moreland A, Abdalla SM, Cohen GH, Friedman MJ, Galea S, Rothbaum AO, Schmidt MG, Vena JE, Kilpatrick DG
JAMA Netw Open. 2022 Sep 1;5(9):e2232556. doi: 10.1001/jamanetworkopen.2022.32556. Epub 2022 Sep 1.
PMID: 36125808

Deimplementation of Benzodiazepine Prescribing in Posttraumatic Stress Disorder in the Veterans Health Administration.
Bernardy NC, Friedman MJ, Lund BC
J Clin Psychiatry. 2022 Mar 14;83(3) pii: 21m14128. doi: 10.4088/JCP.21m14128. Epub 2022 Mar 14.
PMID: 36036650

Decoding Shared Versus Divergent Transcriptomic Signatures Across Cortico-Amygdala Circuitry in PTSD and Depressive Disorders.
Jaffe AE, Tao R, Page SC, Maynard KR, Pattie EA, Nguyen CV, Deep-Soboslay A, Bharadwaj R, Young KA, Friedman MJ, Williamson DE, Traumatic Stress Brain Research Group, Shin JH, Hyde TM, Martinowich K, Kleinman JE
Am J Psychiatry. 2022 Sep;179(9):673-686. doi: 10.1176/appi.ajp.21020162. Epub 2022 Jul 6.
PMID: 35791611

Risk factors for suicide in the Vietnam-era twin registry.
Forsberg CW, Estrada SA, Baraff A, Magruder KM, Vaccarino V, Litz BT, Friedman MJ, Goldberg J, Smith NL
Suicide Life Threat Behav. 2022 Aug;52(4):631-641. doi: 10.1111/sltb.12848. Epub 2022 May 2.
PMID: 35499385

Comparison of Prolonged Exposure vs Cognitive Processing Therapy for Treatment of Posttraumatic Stress Disorder Among US Veterans: A Randomized Clinical Trial.
Schnurr PP, Chard KM, Ruzek JI, Chow BK, Resick PA, Foa EB, Marx BP, Friedman MJ, Bovin MJ, Caudle KL, Castillo D, Curry KT, Hollifield M, Huang GD, Chee CL, Astin MC, Dickstein B, Renner K, Clancy CP, Collie C, Maieritsch K, Bailey S, Thompson K, Messina M, Franklin L, Lindley S, Kattar K, Luedtke B, Romesser J, McQuaid J, Sylvers P, Varkovitzky R, Davis L, MacVicar D, Shih MC
JAMA Netw Open. 2022 Jan 4;5(1):e2136921. doi: 10.1001/jamanetworkopen.2021.36921. Epub 2022 Jan 4.
PMID: 35044471

Instruments for Measuring Violence on Acute Inpatient Psychiatric Units: Review and Recommendations.
Mistler LA, Friedman MJ
Psychiatr Serv. 2022 Jun;73(6):650-657. doi: 10.1176/ Epub 2021 Sep 15.
PMID: 34521209

Increased Smoking Cessation Among Veterans With Large Decreases in Posttraumatic Stress Disorder Severity.
Salas J, Gebauer S, Gillis A, van den Berk-Clark C, Schneider FD, Schnurr PP, Friedman MJ, Norman SB, Tuerk PW, Cohen BE, Lustman PJ, Scherrer JF
Nicotine Tob Res. 2022 Feb 1;24(2):178-185. doi: 10.1093/ntr/ntab179.
PMID: 34477205

Does COVID-19 count?: Defining Criterion A trauma for diagnosing PTSD during a global crisis.
Norrholm SD, Zalta A, Zoellner L, Powers A, Tull MT, Reist C, Schnurr PP, Weathers F, Friedman MJ
Depress Anxiety. 2021 Sep;38(9):882-885. doi: 10.1002/da.23209.
PMID: 34469042

Improving the Assessment of COVID-19-Associated Posttraumatic Stress Disorder.
Marx BP, Schnurr PP, Friedman MJ
JAMA Psychiatry. 2021 Jul 1;78(7):795. doi: 10.1001/jamapsychiatry.2021.1123.
PMID: 34076692

Transcriptomic organization of the human brain in post-traumatic stress disorder.
Girgenti MJ, Wang J, Ji D, Cruz DA, Traumatic Stress Brain Research Group, Stein MB, Gelernter J, Young KA, Huber BR, Williamson DE, Friedman MJ, Krystal JH, Zhao H, Duman RS
Nat Neurosci. 2021 Jan;24(1):24-33. doi: 10.1038/s41593-020-00748-7. Epub 2020 Dec 21.
PMID: 33349712

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