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Gregory J. Tsongalis, BS, MS, PhD

Title(s):
Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations:
Director, Clinical Genomics and Advanced Technology (CGAT)

Department(s):
Pathology and Laboratory Medicine

Education:
Univ. of Massachusetts, Amherst, BS, 1984
Quinnipiac College, MHS, 1986
Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Programs:
Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine

Websites:
DHMC-CGAT.com

Contact Information:

Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 4th floor
Phone: 603-650-5498
Fax: 603-650-6120
Email: Gregory.J.Tsongalis@hitchcock.org

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email: amber.j.erskine@hitchcock.org


Professional Interests:

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information:

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732


Selected Publications:

 

Ductal Carcinoma in Situ Biomarkers in a Precision Medicine Era: Current and Future Molecular-Based Testing.
Shee K, Muller KE, Marotti J, Miller TW, Wells WA, Tsongalis GJ
Am J Pathol. 2018 Oct 29; pii: S0002-9440(18)30558-3. doi: 10.1016/j.ajpath.2018.08.020. Epub 2018 Oct 29.
PMID: 30385093

Identifying aerosolized cyanobacteria in the human respiratory tract: A proposed mechanism for cyanotoxin-associated diseases.
Facciponte DN, Bough MW, Seidler D, Carroll JL, Ashare A, Andrew AS, Tsongalis GJ, Vaickus LJ, Henegan PL, Butt TH, Stommel EW
Sci Total Environ. 2018 Dec 15;645:1003-1013. doi: 10.1016/j.scitotenv.2018.07.226. Epub 2018 Jul 20.
PMID: 30248825

Implementation of Multicolor Melt Curve Analysis for High-Risk Human Papilloma Virus Detection in Low- and Middle-Income Countries: A Pilot Study for Expanded Cervical Cancer Screening in Honduras.
Turner SA, Deharvengt SJ, Lyons KD, Espinal JAP, LaRochelle EPM, Bejarano S, Kennedy L, Tsongalis GJ
J Glob Oncol. 2018 Sep;(4):1-8. doi: 10.1200/JGO.17.00035. Epub 2017 Aug 28.
PMID: 30241169

Maternally inherited 133kb deletion of 14q32 causing Kagami-Ogata syndrome.
Jung HS, Vallee SE, Dinulos MB, Tsongalis GJ, Lefferts JA
J Hum Genet. 2018 Sep 19; doi: 10.1038/s10038-018-0506-z. Epub 2018 Sep 19.
PMID: 30232357

Identifying Associations between Somatic Mutations and Clinicopathologic Findings in Lung Cancer Pathology Reports.
Kumar N, Tafe LJ, Higgins JH, Peterson JD, de Abreu FB, Deharvengt SJ, Tsongalis GJ, Amos CI, Hassanpour S
Methods Inf Med. 2018 Feb;57(1):63-73. doi: 10.3414/ME17-01-0039. Epub 2018 Apr 5.
PMID: 29621832

Rural distribution of human papilloma virus in low- and middle-income countries.
Atkinson A, Studwell C, Bejarano S, Castellon AMZ, Espinal JAP, Deharvengt S, LaRochelle EPM, Kennedy LS, Tsongalis GJ
Exp Mol Pathol. 2018 Apr;104(2):146-150. doi: 10.1016/j.yexmp.2018.03.001. Epub 2018 Mar 16.
PMID: 29551573

Potential of STAT Somatic Mutation Testing at Resection.
Al-Turkmani MR, Schutz SN, Tsongalis GJ
Clin Chem. 2018 May;64(5):865-866. doi: 10.1373/clinchem.2017.285759. Epub 2018 Feb 26.
PMID: 29483108

Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non-Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing.
Shajani-Yi Z, de Abreu FB, Peterson JD, Tsongalis GJ
Neoplasia. 2018 Mar;20(3):256-262. doi: 10.1016/j.neo.2017.12.005. Epub 2018 Feb 16.
PMID: 29454261

Somatic Mutation Analysis of Human Cancers: Challenges in Clinical Practice.
Tsongalis GJ, Coleman WB
J Clin Pharmacol. 2017 Oct;57 Suppl 10:S60-S66. doi: 10.1002/jcph.934.
PMID: 28921651

Somatic mutation analysis in melanoma using targeted next generation sequencing.
Miraflor AP, de Abreu FB, Peterson JD, Turner SA, Amos CI, Tsongalis GJ, Yan S
Exp Mol Pathol. 2017 Oct;103(2):172-177. doi: 10.1016/j.yexmp.2017.08.006. Epub 2017 Aug 16.
PMID: 28822769