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Gregory J. Tsongalis, BS, MS, PhD

Professor of Pathology & Laboratory Medicine

Additional Titles/Positions/Affiliations:
Director, Clinical Genomics and Advanced Technology (CGAT)

Pathology & Laboratory Medicine

Univ. of Massachusetts, Amherst, BS, 1984
Quinnipiac College, MHS, 1986
Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine


Contact Information:

Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 4th floor
Phone: 603-650-5498
Fax: 603-650-6120
Email: Gregory.J.Tsongalis@hitchcock.org

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email: amber.j.erskine@hitchcock.org

Professional Interests:

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information:

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732

Selected Publications:


BRAF V600E mutations are not an oncogenic driver of solitary xanthogranuloma and reticulohistiocytoma: Testing may be useful in screening for Erdheim-Chester disease.
Hoyt BS, Yan S, Linos KD, Momtahen S, Sriharan A, Tran TN, Tsongalis GJ, O'Meara RR, Green DC, LeBlanc RE
Exp Mol Pathol. 2019 Oct 19;111:104320. doi: 10.1016/j.yexmp.2019.104320. Epub 2019 Oct 19.
PMID: 31639332

Third generation sequencing in the clinical laboratory: Exploring the advantages and challenges of nanopore sequencing.
Petersen LM, Martin IW, Moschetti WE, Kershaw CM, Tsongalis GJ
J Clin Microbiol. 2019 Oct 16; pii: JCM.01315-19. doi: 10.1128/JCM.01315-19. Epub 2019 Oct 16.
PMID: 31619531

How close are miRNAs from clinical practice? A perspective on the diagnostic and therapeutic market.
Bonneau E, Neveu B, Kostantin E, Tsongalis GJ, De Guire V
EJIFCC. 2019 Jun;30(2):114-127. Epub 2019 Jun 24.
PMID: 31263388

Screening for Human Papillomavirus in a Low- and Middle-Income Country.
Atkinson AE, Mandujano CAM, Bejarano S, Kennedy LS, Tsongalis GJ
J Glob Oncol. 2019 May;5:JGO1800233. doi: 10.1200/JGO.18.00233.
PMID: 31050922

Pancreatic cyst fluid harboring a KRAS mutation.
Al-Turkmani MR, Gordon SR, Smith KD, Tsongalis GJ, Liu X
Cold Spring Harb Mol Case Stud. 2019 Apr;5(2) pii: a003830. doi: 10.1101/mcs.a003830. Epub 2019 Apr 1.
PMID: 30936197

Design of peptide nucleic acid probes on plasmonic gold nanorods for detection of circulating tumor DNA point mutations.
Tadimety A, Zhang Y, Kready KM, Palinski TJ, Tsongalis GJ, Zhang JXJ
Biosens Bioelectron. 2019 Apr 1;130:236-244. doi: 10.1016/j.bios.2019.01.045. Epub 2019 Jan 29.
PMID: 30769288

Significant Expansion of Real-Time PCR Multiplexing with Traditional Chemistries using Amplitude Modulation.
Rajagopal A, Yurk D, Shin C, Menge K, Jacky L, Fraser S, Tombrello TA, Tsongalis GJ
Sci Rep. 2019 Jan 31;9(1):1053. doi: 10.1038/s41598-018-37732-y. Epub 2019 Jan 31.
PMID: 30705333

Ductal Carcinoma in Situ Biomarkers in a Precision Medicine Era: Current and Future Molecular-Based Testing.
Shee K, Muller KE, Marotti J, Miller TW, Wells WA, Tsongalis GJ
Am J Pathol. 2019 May;189(5):956-965. doi: 10.1016/j.ajpath.2018.08.020. Epub 2018 Oct 29.
PMID: 30385093

Identifying aerosolized cyanobacteria in the human respiratory tract: A proposed mechanism for cyanotoxin-associated diseases.
Facciponte DN, Bough MW, Seidler D, Carroll JL, Ashare A, Andrew AS, Tsongalis GJ, Vaickus LJ, Henegan PL, Butt TH, Stommel EW
Sci Total Environ. 2018 Dec 15;645:1003-1013. doi: 10.1016/j.scitotenv.2018.07.226. Epub 2018 Jul 20.
PMID: 30248825

Implementation of Multicolor Melt Curve Analysis for High-Risk Human Papilloma Virus Detection in Low- and Middle-Income Countries: A Pilot Study for Expanded Cervical Cancer Screening in Honduras.
Turner SA, Deharvengt SJ, Lyons KD, Espinal JAP, LaRochelle EPM, Bejarano S, Kennedy L, Tsongalis GJ
J Glob Oncol. 2018 Sep;4:1-8. doi: 10.1200/JGO.17.00035. Epub 2017 Aug 28.
PMID: 30241169

View more publications on PubMed