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Gregory J. Tsongalis, BS, MS, PhD

Title(s)
Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations
Vice Chair for Research and
Director, Clinical Genomics and Advanced Technology (CGAT)

Department(s)
Pathology and Laboratory Medicine

Education
Univ. of Massachusetts, Amherst, BS, 1984
Quinnipiac College, MHS, 1986
Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Programs
Dartmouth Cancer Center
Program in Experimental and Molecular Medicine

Websites DHMC-CGAT.com

Contact Information

Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 4th floor
Phone: 603-650-5498
Fax: 603-650-6120
Email: Gregory.J.Tsongalis@hitchcock.org

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email: amber.j.erskine@hitchcock.org


Professional Interests

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732


Selected Publications

 

Nanopore-based random genomic sampling for intraoperative molecular diagnosis.
Emiliani FE, Ismail AAO, Hughes EG, Tsongalis GJ, Zanazzi GJ, Lin CC
Genome Med. 2025 Jan 20;17(1):6. doi: 10.1186/s13073-025-01427-7. Epub 2025 Jan 20.
PMID: 39833913

Prevalence of Human Papillomavirus-Associated Head and Neck Cancer in Rwanda: A 10-Year Review.
Rubagumya F, Businge L, Hopman WH, Murenzi G, Uwimbabazi A, Kwizera V, Imuragire J, Muvunyi TZ, Izimukwiye I, Adedimeji A, Barney RE, Tsongalis GJ, Chamberlin MD, Anastos K, Kabarriti R
Cancer Med. 2024 Nov;13(21):e70423. doi: 10.1002/cam4.70423.
PMID: 39530527

Angiomyolipomatous Lesions of the Nasal Cavity (Sinonasal Angioleiomyoma with Adipocytic Differentiation): A Multi-Institutional Immunohistochemical and Molecular Study.
Jones VM, Thompson LDR, Pettus JR, Green DC, Lefferts JA, Shah PS, Tsongalis GJ, Sajed DP, Guilmette JM, Lewis JS Jr, Fisch AS, Tafe LJ, Kerr DA
Head Neck Pathol. 2024 Oct 14;18(1):93. doi: 10.1007/s12105-024-01700-y. Epub 2024 Oct 14.
PMID: 39400771

An initial game-theoretic assessment of enhanced tissue preparation and imaging protocols for improved deep learning inference of spatial transcriptomics from tissue morphology.
Fatemi MY, Lu Y, Diallo AB, Srinivasan G, Azher ZL, Christensen BC, Salas LA, Tsongalis GJ, Palisoul SM, Perreard L, Kolling FW 4th, Vaickus LJ, Levy JJ
Brief Bioinform. 2024 Sep 23;25(6) doi: 10.1093/bib/bbae476.
PMID: 39367648

Angiomyolipomatous Lesions of the Nasal Cavity (Sinonasal Angioleiomyoma with Adipocytic Differentiation): A Multi-Institutional Immunohistochemical and Molecular Study.
Jones VM, Thompson LDR, Pettus JR, Green DC, Lefferts JA, Shah PS, Tsongalis GJ, Sajed DP, Guilmette JM, Lewis JS, Fisch AS, Tafe LJ, Kerr DA
Res Sq. 2024 Sep 8; pii: rs.3.rs-4843357. doi: 10.21203/rs.3.rs-4843357/v1. Epub 2024 Sep 8.
PMID: 39281855

Implementation of a pharmacist-guided pharmacogenomics dosing service at a rural NCI-designated comprehensive cancer center.
Green JK, Hackett LJ, Green DC, Deharvengt SJ, Brooks GA, Khan WA, Tsongalis GJ, Lewis LD, Shah PS
J Oncol Pharm Pract. 2024 Sep 4;:10781552241281936. doi: 10.1177/10781552241281936. Epub 2024 Sep 4.
PMID: 39228222

High-Risk HPV Screening Initiative in Kosovo-A Way to Optimize HPV Vaccination for Cervical Cancer.
Bentz JL, Barney RE, Georgantzoglou N, Manxhuka-Kerliu S, Ibishi VA, Dacaj-Elshani B, Bejarano S, Palumbo PE, Suresh A, LaRochelle EPM, Keegan WP, Wilson TL, Dokus BJ, Hershberger KC, Gallagher TL, Allen SF, Palisoul SM, Steinmetz HB, Kennedy LS, Tsongalis GJ
Diseases. 2024 Aug 19;12(8) doi: 10.3390/diseases12080189. Epub 2024 Aug 19.
PMID: 39195188

A Droplet Digital Polymerase Chain Reaction-Based Tool to Aid in Melanoma Diagnosis.
McFadden JR, Salem I, Stevanovic M, Barney RE, Chaudhari AS, Chambers MA, O'Hern K, Cloutier JM, Yan S, Ramos-Rodriguez AJ, Kerr DA, Momtahen S, LeBlanc RE, Tsongalis GJ, Hughes EG, Sriharan A
Arch Pathol Lab Med. 2024 Aug 1; doi: 10.5858/arpa.2024-0027-OA. Epub 2024 Aug 1.
PMID: 39084636

Validation and Implementation of a Somatic-Only Tumor Exome for Routine Clinical Application.
Shah PS, Hughes EG, Sukhadia SS, Green DC, Houde BE, Tsongalis GJ, Tafe LJ
J Mol Diagn. 2024 Sep;26(9):815-824. doi: 10.1016/j.jmoldx.2024.05.013. Epub 2024 Jul 6.
PMID: 38972591

Analytical validation of a semi-automated methodology for quantitative measurement of SARS-CoV-2 RNA in wastewater collected in northern New England.
Robbins AA, Gallagher TL, Toledo DM, Hershberger KC, Salmela SM, Barney RE, Szczepiorkowski ZM, Tsongalis GJ, Martin IW, Hubbard JA, Lefferts JA
Microbiol Spectr. 2024 Jun 4;12(6):e0112223. doi: 10.1128/spectrum.01122-23. Epub 2024 May 15.
PMID: 38747589

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