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Gregory J. Tsongalis, BS, MS, PhD

Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations
Vice Chair for Research and
Director, Clinical Genomics and Advanced Technology (CGAT)

Pathology and Laboratory Medicine

Univ. of Massachusetts, Amherst, BS, 1984
Quinnipiac College, MHS, 1986
Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine


Contact Information

Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 4th floor
Phone: 603-650-5498
Fax: 603-650-6120

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email:

Professional Interests

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732

Selected Publications


Predicting oncogene mutations of lung cancer using deep learning and histopathologic features on whole-slide images.
Tomita N, Tafe LJ, Suriawinata AA, Tsongalis GJ, Nasir-Moin M, Dragnev K, Hassanpour S
Transl Oncol. 2022 Oct;24:101494. doi: 10.1016/j.tranon.2022.101494. Epub 2022 Jul 26.
PMID: 35905641

Wastewater-Based SARS-CoV-2 Surveillance in Northern New England.
Toledo DM, Robbins AA, Gallagher TL, Hershberger KC, Barney RE, Salmela SM, Pilcher D, Cervinski MA, Nerenz RD, Szczepiorkowski ZM, Tsongalis GJ, Lefferts JA, Martin IW, Hubbard JA
Microbiol Spectr. 2022 Apr 27;10(2):e0220721. doi: 10.1128/spectrum.02207-21. Epub 2022 Apr 12.
PMID: 35412387

Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
Parsons DW, Janeway KA, Patton DR, Winter CL, Coffey B, Williams PM, Roy-Chowdhuri S, Tsongalis GJ, Routbort M, Ramirez NC, Saguilig L, Piao J, Alonzo TA, Berg SL, Fox E, Hawkins DS, Abrams JS, Mooney M, Takebe N, Tricoli JV, Seibel NL, NCI-COG Pediatric MATCH Team.
J Clin Oncol. 2022 Jul 10;40(20):2224-2234. doi: 10.1200/JCO.21.02838. Epub 2022 Mar 30.
PMID: 35353553

Living the best of both worlds: A personal scientific journey.
Tsongalis GJ
FASEB Bioadv. 2022 Feb;4(2):95-101. doi: 10.1096/fba.2021-00103. Epub 2021 Nov 5.
PMID: 35141473

Mixed Effects Machine Learning Models for Colon Cancer Metastasis Prediction using Spatially Localized Immuno-Oncology Markers.
Levy JJ, Bobak CA, Nasir-Moin M, Veziroglu EM, Palisoul SM, Barney RE, Salas LA, Christensen BC, Tsongalis GJ, Vaickus LJ
Pac Symp Biocomput. 2022;27:175-186.
PMID: 34890147

Plasmonic Nanoparticle Conjugation for Nucleic Acid Biosensing.
Tadimety A, Zhang Y, Molinski JH, Palinski TJ, Tsongalis GJ, Zhang JXJ
Methods Mol Biol. 2022;2393:73-87. doi: 10.1007/978-1-0716-1803-5_5.
PMID: 34837175

CRISPR-cas13 enzymology rapidly detects SARS-CoV-2 fragments in a clinical setting.
Khan WA, Barney RE, Tsongalis GJ
J Clin Virol. 2021 Dec;145:105019. doi: 10.1016/j.jcv.2021.105019. Epub 2021 Oct 28.
PMID: 34753073

High-Throughput CRISPR-Cas13 SARS-CoV-2 Test.
Manning BJ, Khan WA, Peña JM, Fiore ES, Boisvert H, Tudino MC, Barney RE, Wilson MK, Singh S, Mowatt JA, Thompson HJ, Tsongalis GJ, Blake WJ
Clin Chem. 2021 Dec 30;68(1):172-180. doi: 10.1093/clinchem/hvab238.
PMID: 34718481

Mammary-type Myofibroblastoma with Leiomyomatous Differentiation: A Rare Variant with Potential Pitfalls.
Strait AM, Bridge JA, Iafrate AJ, Li MM, Xu F, Tsongalis GJ, Linos K
Int J Surg Pathol. 2022 Apr;30(2):200-206. doi: 10.1177/10668969211031309. Epub 2021 Aug 2.
PMID: 34338561

Reducing dermal exposure to agrochemical carcinogens using a fluorescent dye-based intervention among subsistence farmers in rural Honduras.
Flynn TG, Dunaway CM, LaRochelle E, Lyons K, Kennedy LS, Romano ME, Li Z, Spaller MR, Cervinski MA, Bejarano S, Tsongalis GJ, Huyck KL
Int J Hyg Environ Health. 2021 May;234:113734. doi: 10.1016/j.ijheh.2021.113734. Epub 2021 Mar 31.
PMID: 33799075

View more publications on PubMed