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Gregory J. Tsongalis, BS, MS, PhD

Title(s):
Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations:
Director, Clinical Genomics and Advanced Technology (CGAT)

Department(s):
Pathology and Laboratory Medicine

Education:
Univ. of Massachusetts, Amherst, BS, 1984
Quinnipiac College, MHS, 1986
Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Programs:
Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine

Websites:
DHMC-CGAT.com

Contact Information:

Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 4th floor
Phone: 603-650-5498
Fax: 603-650-6120
Email: Gregory.J.Tsongalis@hitchcock.org

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email: amber.j.erskine@hitchcock.org

Professional Interests:

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information:

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732

Selected Publications:
 

Use of Biosynthetic Controls as Performance Standards for Next-Generation Sequencing Assays of Somatic Tumors: A Multilaboratory Study.
De Abreu FB, Peterson JD, Deharvengt SJ, Daber R, Sarsani VK, Spotlow V, Harrington RD, Lih CJ, Williams PM, Bouk CH, Konigshofer Y, Huang C, Anekella B, Davis L, Garlick RK, Ferreira-Gonzalez A, Dumur CI, Fernandes H, Haralampu S, Tsongalis GJ
J Appl Lab Med. 2017 Sep 1;2(2):138-149. doi: 10.1373/jalm.2017.023085.
PMID: 32630970

Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board.
Bernhardt EB, Chamberlin MD, Gorlov IP, de Abreu FB, Bloch KJ, Peterson JD, Tsongalis GJ, Shirai K, Dragnev KH, Miller TW, Tafe LJ
Pract Lab Med. 2020 Aug;21:e00174. doi: 10.1016/j.plabm.2020.e00174. Epub 2020 Jun 12.
PMID: 32613070

Molecular genetic profiling reveals novel association between FLT3 mutation and survival in glioma.
Shee K, Chambers M, Hughes EG, Almiron DA, Deharvengt SJ, Green D, Lefferts JA, Andrew AS, Hickey WF, Tsongalis GJ
J Neurooncol. 2020 Jun 24; doi: 10.1007/s11060-020-03567-9. Epub 2020 Jun 24.
PMID: 32583303

Comparison of Tissue Molecular Biomarker Testing Turnaround Times and Concordance Between Standard of Care and the Biocartis Idylla Platform in Patients With Colorectal Cancer.
Tsongalis GJ, Al Turkmani MR, Suriawinata M, Babcock MJ, Mitchell K, Ding Y, Scicchitano L, Tira A, Buckingham L, Atkinson S, Lax A, Aisner DL, Davies KD, Wood HN, O'Neill SS, Levine EA, Sequeira J, Harada S, DeFrank G, Paluri R, Tan BA, Colabella H, Snead C, Cruz-Correa M, Ramirez V, Rojas A, Huang H, Mackinnon AC, Garcia FU, Cavone SM, Elfahal M, Abel G, Vasef MA, Judd A, Linder MW, Alkhateeb K, Skinner WL, Boccia R, Patel K
Am J Clin Pathol. 2020 Jul 7;154(2):266-276. doi: 10.1093/ajcp/aqaa044.
PMID: 32525522

HPV, vaccines, and cervical cancer in a low- and middle-income country.
Petersen LM, Fenton JM, Kennedy LS, LaRochelle EPM, Bejarano S, Tsongalis GJ
Curr Probl Cancer. 2020 May 28;:100605. doi: 10.1016/j.currproblcancer.2020.100605. Epub 2020 May 28.
PMID: 32507365

Clinical Validation of a 106-SNV MALDI-ToF MS Pharmacogenomic Panel.
Williams GR, Cook L, Lewis LD, Tsongalis GJ, Nerenz RD
J Appl Lab Med. 2020 May 1;5(3):454-466. doi: 10.1093/jalm/jfaa018.
PMID: 32445367

Implementation of an Emergency Use Authorization Test During an Impending National Crisis.
Lefferts JA, Gutmann EJ, Martin IW, Wells WA, Tsongalis GJ
J Mol Diagn. 2020 Jul;22(7):844-846. doi: 10.1016/j.jmoldx.2020.05.001. Epub 2020 May 14.
PMID: 32417222

Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.
Al-Turkmani MR, Suriawinata MA, Deharvengt SJ, Green DC, Black CC, Shirai K, Dragnev KH, Tsongalis GJ
Pract Lab Med. 2020 May;20:e00156. doi: 10.1016/j.plabm.2020.e00156. Epub 2020 Mar 2.
PMID: 32181314

Feasibility of Brigade-Style, Multiphasic Cancer Screening in Rural Honduras.
Lyons KD, Kennedy LS, Larochelle EPM, Tsongalis GJ, Reyes HS, Zuniga-Moya JC, Chamberlin MD, Bruce ML, Bejarno S
JCO Glob Oncol. 2020 Mar;6:453-461. doi: 10.1200/JGO.19.00396.
PMID: 32160013

A case of molecularly confirmed BAP1 inactivated melanocytic tumor with retention of immunohistochemical expression: A confounding factor.
Linos K, Atkinson AE, Yan S, Tsongalis GJ, Lefferts JA
J Cutan Pathol. 2020 May;47(5):485-489. doi: 10.1111/cup.13642. Epub 2020 Jan 23.
PMID: 31891422

View more publications on PubMed