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Gregory J. Tsongalis, BS, MS, PhD

Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations:
Vice Chair for Research and
Director, Clinical Genomics and Advanced Technology (CGAT)

Pathology and Laboratory Medicine

Univ. of Massachusetts, Amherst, BS, 1984
Quinnipiac College, MHS, 1986
Univ. of Medicine and Dentistry of New Jersey, PhD 1990
Uniiv. of North Carolina, Chapel Hill, post-doctoral 1990-1994

Norris Cotton Cancer Center
Program in Experimental and Molecular Medicine


Contact Information:

Department of Pathology and Laboratory Medicine
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 4th floor
Phone: 603-650-5498
Fax: 603-650-6120

Assistant: Amber Erskine
Asst. Phone: 603-650-6821
Asst. Email:

Professional Interests:

Development of advanced diagnostic technologies and disease biomarker discovery.

Grant Information:

01/2014-12/30/15; Molecular profiling of tumor and ctDNA, riends of NCCC Scholar $50,000

03/01/13-01/31/2018; 1P20GM104416, Investigator / 2% COBRE Center for Molecular Epidemiology, Federal Direct Costs: $1,793,732

Selected Publications:


Mammary-type Myofibroblastoma with Leiomyomatous Differentiation: A Rare Variant with Potential Pitfalls.
Strait AM, Bridge JA, Iafrate AJ, Li MM, Xu F, Tsongalis GJ, Linos K
Int J Surg Pathol. 2021 Aug 2;:10668969211031309. doi: 10.1177/10668969211031309. Epub 2021 Aug 2.
PMID: 34338561

Reducing dermal exposure to agrochemical carcinogens using a fluorescent dye-based intervention among subsistence farmers in rural Honduras.
Flynn TG, Dunaway CM, LaRochelle E, Lyons K, Kennedy LS, Romano ME, Li Z, Spaller MR, Cervinski MA, Bejarano S, Tsongalis GJ, Huyck KL
Int J Hyg Environ Health. 2021 May;234:113734. doi: 10.1016/j.ijheh.2021.113734. Epub 2021 Mar 31.
PMID: 33799075

Evaluation of a Next-Generation Sequencing Metagenomics Assay to Detect and Quantify DNA Viruses in Plasma from Transplant Recipients.
Sam SS, Rogers R, Gillani FS, Tsongalis GJ, Kraft CS, Caliendo AM
J Mol Diagn. 2021 Jun;23(6):719-731. doi: 10.1016/j.jmoldx.2021.02.008. Epub 2021 Mar 9.
PMID: 33706010

Implementation of Reverse Transcriptase PCR Testing for Severe Acute Respiratory Syndrome Coronavirus 2 under the US Food and Drug Administration Emergency Use Authorization.
Lefferts JA, Allen SF, Steinmetz HB, Tsongalis GJ
Clin Chem. 2021 Jan 30;67(2):434-435. doi: 10.1093/clinchem/hvaa278.
PMID: 33315063

Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board.
Bernhardt EB, Chamberlin MD, Gorlov IP, de Abreu FB, Bloch KJ, Peterson JD, Tsongalis GJ, Shirai K, Dragnev KH, Miller TW, Tafe LJ
Pract Lab Med. 2020 Aug;21:e00174. doi: 10.1016/j.plabm.2020.e00174. Epub 2020 Jun 12.
PMID: 32613070

Molecular genetic profiling reveals novel association between FLT3 mutation and survival in glioma.
Shee K, Chambers M, Hughes EG, Almiron DA, Deharvengt SJ, Green D, Lefferts JA, Andrew AS, Hickey WF, Tsongalis GJ
J Neurooncol. 2020 Jul;148(3):473-480. doi: 10.1007/s11060-020-03567-9. Epub 2020 Jun 24.
PMID: 32583303

Comparison of Tissue Molecular Biomarker Testing Turnaround Times and Concordance Between Standard of Care and the Biocartis Idylla Platform in Patients With Colorectal Cancer.
Tsongalis GJ, Al Turkmani MR, Suriawinata M, Babcock MJ, Mitchell K, Ding Y, Scicchitano L, Tira A, Buckingham L, Atkinson S, Lax A, Aisner DL, Davies KD, Wood HN, O'Neill SS, Levine EA, Sequeira J, Harada S, DeFrank G, Paluri R, Tan BA, Colabella H, Snead C, Cruz-Correa M, Ramirez V, Rojas A, Huang H, Mackinnon AC, Garcia FU, Cavone SM, Elfahal M, Abel G, Vasef MA, Judd A, Linder MW, Alkhateeb K, Skinner WL, Boccia R, Patel K
Am J Clin Pathol. 2020 Jul 7;154(2):266-276. doi: 10.1093/ajcp/aqaa044.
PMID: 32525522

HPV, vaccines, and cervical cancer in a low- and middle-income country.
Petersen LM, Fenton JM, Kennedy LS, LaRochelle EPM, Bejarano S, Tsongalis GJ
Curr Probl Cancer. 2020 Dec;44(6):100605. doi: 10.1016/j.currproblcancer.2020.100605. Epub 2020 May 28.
PMID: 32507365

Clinical Validation of a 106-SNV MALDI-ToF MS Pharmacogenomic Panel.
Williams GR, Cook L, Lewis LD, Tsongalis GJ, Nerenz RD
J Appl Lab Med. 2020 May 1;5(3):454-466. doi: 10.1093/jalm/jfaa018.
PMID: 32445367

Implementation of an Emergency Use Authorization Test During an Impending National Crisis.
Lefferts JA, Gutmann EJ, Martin IW, Wells WA, Tsongalis GJ
J Mol Diagn. 2020 Jul;22(7):844-846. doi: 10.1016/j.jmoldx.2020.05.001. Epub 2020 May 14.
PMID: 32417222

View more publications on PubMed