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Joseph A Paydarfar, MD

Title(s):
Associate Professor of Surgery

Additional Titles/Positions/Affiliations:
Chief, Section of Otolaryngology, Audiology & Maxillofacial Surgery
Adjunct Associate Professor of Engineering

Department(s):
Surgery

Education:
BSE Duke University
MD Duke University
Residency in Otolaryngology - Head & Neck Surgery, Washington University in St. Louis
Fellowship in Microvascular/Head & Neck Surgery, Hahnemann University Hospital

Programs:
Norris Cotton Cancer Center

Websites:
Halter lab:
https://sites.google.com/dartmouth.edu/halter-lab/
https://engineering.dartmouth.edu/research/enabling-technologies-for-effective-image-guided-surgical-navigation

NCBI Bibliography:
https://www.ncbi.nlm.nih.gov/myncbi/16i0inv_uthkY/bibliography/public/

Contact Information:

Section of Otolaryngology, Dartmouth Hitchcock Medical Center
1 Medical Center Drive
Lebanon NH 03756

Phone: 6036508123


Grant Information:

Ongoing Research Support
Project number: 287103.594000.2012
Contact Principal Investigator: Joseph Paydarfar MD
Source of support: Norris Cotton Cancer Center Pilot Award
Title of project/subproject: Development and validation of a CT compatible retractor system for image guided transoral robotic cancer resection
Dates of approved/proposed project: 8/1/2019 – 6/30/2021

Project Number: 1R21CA246158-01
Sponsor/Funding Source: NIH
Contact Principal Investigator: Ryan Halter PhD
Award Period: 07/01/20 – 06/30/22
Project Title: Image guidance for trans-oral robotic surgery
Major Goals: The overarching aims of this program are to reduce complications and improve outcomes for minimally invasive robot-assisted throat cancer surgery by enhancing the surgeon’s ability to assess tumor extent and localize vascular and other critical anatomic structures. We aim to examine the feasibility of image guidance technology by developing CT compatible instrumentation and taking advantage of existing intraoperative CT and surgical navigation resources to develop a framework for image-guided trans-oral robotic surgery (igTORS).


Completed Research Support
Norris Cotton Cancer Center Hopeman Fund for Clinical Research (Paydarfar/Halter) 1/1/2018-11/30/2019
Title: Upper aerodigestive tract pressure measurement during operative laryngoscopy for cancer resection. Goal: Develop a pressure sensing laryngoscope to assess typical forces imparted on the scope during laryngoscopy.

Department of Surgery Faculty Development Award, Dartmouth-Hitchcock Medical Center 4/18 – 4/19
Title: Toward improving outcomes in trans-oral surgery for head and neck cancer.
Goal: Provide FTE salary support for laryngoscopy pressure study, clinical outcomes of TORS/TOS review at Dartmouth Hitchcock, and optical imaging study examining a unique EGFR affibody for head and neck SCCa.

Norris Cotton Cancer Center Development Funds (Paydarfar/Halter/Pastel)
2017
Title: Testing the Efficacy of Image Guidance for Trans-Oral Surgery.
Goal: The aim of this study was to evaluate the benefit of intraoperative imaging during laryngoscopy-based procedures on cadaver models.
Role: Co-PI

SYNERGY Pilot and Collaborative Studies Program (Paydarfar/Halter)
2015-2016
The Dartmouth Clinical and Translational Science Institute
Title: Improving trans-oral surgical outcomes through intra-operative image guidance.
Goal: Develop a CT/MR compatible laryngoscope to evaluate the potential of intra-operative image guidance for trans-oral surgery

Black C, Paydarfar J. Targeting Aberrant S-Phase Cell Cycle Proteins as a Diagnostic Adjunct and Predictor of Disease Progression in Oral Mucosal Biopsies. NCCC 2009 Prouty Research Grant.

Williams BB, Paydarfar JA, Gosselin B, Jiang S, Swartz HM. EPR Oximetry Measurements in Patients Undergoing Free Flap Reconstruction to Assess Tissue Viability, NCCC 2007 Prouty Research Grant

Paydarfar JA. Wound complications in head and neck surgery – institutional and national outcomes. Dartmouth Hitchcock Medical Center, Department of Surgery, 2005 Harmes Scholarship.

Biography:

Dr. Paydarfar is Chief, Division of Otolaryngology, Audiology and Maxillofacial Surgery at the Dartmouth-Hitchcock Medical Center, Associate Professor of Surgery - Otolaryngology at the Dartmouth Geisel School of Medicine, and Adjunct Associate Professor of Engineering, Thayer School of Engineering at Dartmouth. After obtaining his MD at Duke University he completed his residency in Otolaryngology at Washington University in St. Louis and Head and Neck Oncologic and Reconstructive Fellowship at Hahnemann Hospital in Philadelphia. His clinical interests are in head and neck oncologic and reconstructive surgery, trans-oral laser microsurgery, and trans-oral robotic surgery. His research interests include minimally invasive approaches and surgical navigation in head and neck surgery.


Selected Publications:

 

Image-guided surgery in otolaryngology: A review of current applications and future directions in head and neck surgery.
Bessen SY, Wu X, Sramek MT, Shi Y, Pastel D, Halter R, Paydarfar JA
Head Neck. 2021 Aug;43(8):2534-2553. doi: 10.1002/hed.26743. Epub 2021 May 25.
PMID: 34032338

Clinicopathologic and Genomic Characterization of Inflammatory Myofibroblastic Tumors of the Head and Neck: Highlighting a Novel Fusion and Potential Diagnostic Pitfall.
Kerr DA, Thompson LDR, Tafe LJ, Jo VY, Neyaz A, Divakar P, Paydarfar JA, Pastel DA, Shirai K, John I, Seethala RR, Salgado CM, Deshpande V, Bridge JA, Kashofer K, Brčić I, Linos K
Am J Surg Pathol. 2021 May 18; doi: 10.1097/PAS.0000000000001735. Epub 2021 May 18.
PMID: 34001695

Spontaneous regression of squamous cell carcinoma in the setting of dental infection and needle biopsy.
Divakar P, Khan MJ, Polacco M, Kerr DA, Paydarfar JA
Clin Case Rep. 2020 Oct;8(10):1919-1923. doi: 10.1002/ccr3.3024. Epub 2020 Aug 4.
PMID: 33088519

Tensor Veli Palatinopexy as a Novel Treatment for Eustachian Tube Dysfunction: A Cadaveric Feasibility Study.
Eisen EA, Wu X, Rees CA, Pastel DA, Paydarfar JA, Saunders JE
Otolaryngol Head Neck Surg. 2021 Mar;164(3):652-656. doi: 10.1177/0194599820952407. Epub 2020 Sep 8.
PMID: 32894994

Tumor phantom for training and research in transoral surgery.
Sramek M, Shi Y, Quintanilla E, Wu X, Ponukumati A, Pastel D, Halter R, Paydarfar J
Laryngoscope Investig Otolaryngol. 2020 Aug;5(4):677-682. doi: 10.1002/lio2.426. Epub 2020 Jul 16.
PMID: 32864438

A System for Characterizing Intraoperative Force Distribution During Operative Laryngoscopy.
Ponukumati AS, Wu X, Kahng PW, Skinner J, Paydarfar JA, Halter RJ
IEEE Trans Biomed Eng. 2020 Sep;67(9):2616-2627. doi: 10.1109/TBME.2020.2966954. Epub 2020 Jan 16.
PMID: 31976874

Primary Ewing's sarcoma of the petroclival bone: A case report and literature review.
Schartz D, Divakar P, Tafe L, Paydarfar J
Surg Neurol Int. 2020;11:6. doi: 10.25259/SNI_415_2019. Epub 2020 Jan 10.
PMID: 31966925

Multi-modal Framework for Image-guided Trans-oral Surgery with Intraoperative Imaging and Deformation Modeling.
Wu X, Fels S, Paydarfar JA, Halter RJ, Sanchez CA, Kahng PW, Rees CA, Ponukumati AS, Eisen EA, Pastel DA, Borgard H, Lloyd JE
Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:6975-6978. doi: 10.1109/EMBC.2019.8857322.
PMID: 31947443

Radiation exposure alters airway deformability and bony structure displacement during laryngoscopy.
Rees CA, Wu X, Eisen EA, Pastel DA, Halter RJ, Paydarfar JA
Laryngoscope Investig Otolaryngol. 2019 Dec;4(6):609-616. doi: 10.1002/lio2.311. Epub 2019 Oct 22.
PMID: 31890878

Improving target localization during trans-oral surgery with use of intraoperative imaging.
Kahng PW, Wu X, Ramesh NP, Pastel DA, Halter RJ, Paydarfar JA
Int J Comput Assist Radiol Surg. 2019 May;14(5):885-893. doi: 10.1007/s11548-018-01907-9. Epub 2019 Feb 7.
PMID: 30730029

View more publications on PubMed