Joseph A Paydarfar, MD
Associate Professor of Surgery
Chief, Section of Otolaryngology, Audiology & Maxillofacial Surgery
Adjunct Associate Professor of Engineering
BSE Duke University
MD Duke University
Residency in Otolaryngology - Head & Neck Surgery, Washington University in St. Louis
Fellowship in Microvascular/Head & Neck Surgery, Hahnemann University Hospital
Norris Cotton Cancer Center
Section of Otolaryngology, Dartmouth Hitchcock Medical Center
1 Medical Center Drive
Lebanon NH 03756
Ongoing Research Support
Project number: 287103.594000.2012
Contact Principal Investigator: Joseph Paydarfar MD
Source of support: Norris Cotton Cancer Center Pilot Award
Title of project/subproject: Development and validation of a CT compatible retractor system for image guided transoral robotic cancer resection
Dates of approved/proposed project: 8/1/2019 – 6/30/2021
Project Number: 1R21CA246158-01
Sponsor/Funding Source: NIH
Contact Principal Investigator: Ryan Halter PhD
Award Period: 07/01/20 – 06/30/22
Project Title: Image guidance for trans-oral robotic surgery
Major Goals: The overarching aims of this program are to reduce complications and improve outcomes for minimally invasive robot-assisted throat cancer surgery by enhancing the surgeon’s ability to assess tumor extent and localize vascular and other critical anatomic structures. We aim to examine the feasibility of image guidance technology by developing CT compatible instrumentation and taking advantage of existing intraoperative CT and surgical navigation resources to develop a framework for image-guided trans-oral robotic surgery (igTORS).
Completed Research Support
Norris Cotton Cancer Center Hopeman Fund for Clinical Research (Paydarfar/Halter) 1/1/2018-11/30/2019
Title: Upper aerodigestive tract pressure measurement during operative laryngoscopy for cancer resection. Goal: Develop a pressure sensing laryngoscope to assess typical forces imparted on the scope during laryngoscopy.
Department of Surgery Faculty Development Award, Dartmouth-Hitchcock Medical Center 4/18 – 4/19
Title: Toward improving outcomes in trans-oral surgery for head and neck cancer.
Goal: Provide FTE salary support for laryngoscopy pressure study, clinical outcomes of TORS/TOS review at Dartmouth Hitchcock, and optical imaging study examining a unique EGFR affibody for head and neck SCCa.
Norris Cotton Cancer Center Development Funds (Paydarfar/Halter/Pastel)
Title: Testing the Efficacy of Image Guidance for Trans-Oral Surgery.
Goal: The aim of this study was to evaluate the benefit of intraoperative imaging during laryngoscopy-based procedures on cadaver models.
SYNERGY Pilot and Collaborative Studies Program (Paydarfar/Halter)
The Dartmouth Clinical and Translational Science Institute
Title: Improving trans-oral surgical outcomes through intra-operative image guidance.
Goal: Develop a CT/MR compatible laryngoscope to evaluate the potential of intra-operative image guidance for trans-oral surgery
Black C, Paydarfar J. Targeting Aberrant S-Phase Cell Cycle Proteins as a Diagnostic Adjunct and Predictor of Disease Progression in Oral Mucosal Biopsies. NCCC 2009 Prouty Research Grant.
Williams BB, Paydarfar JA, Gosselin B, Jiang S, Swartz HM. EPR Oximetry Measurements in Patients Undergoing Free Flap Reconstruction to Assess Tissue Viability, NCCC 2007 Prouty Research Grant
Paydarfar JA. Wound complications in head and neck surgery – institutional and national outcomes. Dartmouth Hitchcock Medical Center, Department of Surgery, 2005 Harmes Scholarship.
Dr. Paydarfar is Chief, Division of Otolaryngology, Audiology and Maxillofacial Surgery at the Dartmouth-Hitchcock Medical Center, Associate Professor of Surgery - Otolaryngology at the Dartmouth Geisel School of Medicine, and Adjunct Associate Professor of Engineering, Thayer School of Engineering at Dartmouth. After obtaining his MD at Duke University he completed his residency in Otolaryngology at Washington University in St. Louis and Head and Neck Oncologic and Reconstructive Fellowship at Hahnemann Hospital in Philadelphia. His clinical interests are in head and neck oncologic and reconstructive surgery, trans-oral laser microsurgery, and trans-oral robotic surgery. His research interests include minimally invasive approaches and surgical navigation in head and neck surgery.
First demonstration of a novel nerve-targeting fluorophore in a cohort of ex vivo human tissues.
Fluorescence molecular optomic signatures improve identification of tumors in head and neck specimens.
Predictors of gastrostomy tube placement in patients with head and neck cancer undergoing resection and flap-based reconstruction: systematic review and meta-analysis.
Quantitative Evaluation of Aerosol Generation During In-Office Flexible Laryngoscopy.
Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study.
The submental island flap in head and neck reconstruction: A 10-year experience examining application, oncologic safety, and role of comorbidity.
Quantifying Tumor and Vasculature Deformations during Laryngoscopy.
CT for estimating adequacy of lymph node dissection in patients with squamous cell carcinoma of the head and neck.
First-In-Human Study in Cancer Patients Establishing the Feasibility of Oxygen Measurements in Tumors Using Electron Paramagnetic Resonance With the OxyChip.
Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.