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Todd A MacKenzie, PhD

Professor of Biomedical Data Science
Professor of Medicine
Professor of The Dartmouth Institute

Additional Titles/Positions/Affiliations:
Director of Master's Degree in Health Data Science

Biomedical Data Science
The Dartmouth Institute

PhD (Statistics), McGill University, 1997
MSc (Statistics), McGill University, 1993
BSc, Dalhousie University, 1990

Norris Cotton Cancer Center
Quantitative Biomedical Sciences
The Dartmouth Institute for Health Policy and Clinical Practice


Contact Information:

Section of Clinical Research, HB 7505
One Medical Center Drive
Dartmouth Hitchcock Medical Center
Lebanon NH 03756

Phone: 603-653-3542
Fax: 603-653-3554
Email: Todd.A.MacKenzie@Dartmouth.edu

Professional Interests:

I use data science to help clinical and health services researchers from a vast spectrum of disciplines and specialties which has resulted in 250 publications. The majority of these projects involve comparative effectiveness, clinical trials, association studies, and prediction modeling. I am especially interested in survival (aka, time-to-event) analysis, causal inference and most recently the decline in American longevity.

Courses Taught:

QBS 121: Biostatistics II; a course in statistical modelling (Winter) with Tor Tosteson

Past Teaching:
PH 271 (TDI) "Practice of Statistics in Medicine" with James O'Malley: This course was aimed at junior faculty, post-doctoral fellows and PhD students.

PH 147 (TDI) "Advanced Methods in Health Services Research" with Tracy Onega

PEMM 107 "Biostatistics" : A course in biostatistics I developed for bench and translational scientists in molecular medicine.

Selected Publications:


Weight change and risk of the foundation of National Institute of Health Sarcopenia-defined low lean mass: Data from the National Health and Nutrition examination surveys 1999-2004.
Batsis JA, Petersen CL, Crow RS, Cook SB, Stevens CJ, Seo LM, Brooks E, Mackenzie TA
Clin Nutr. 2019 Nov 4; pii: S0261-5614(19)33125-5. doi: 10.1016/j.clnu.2019.10.032. Epub 2019 Nov 4.
PMID: 31727381

Role of Sex in Determining Treatment Type for Patients Undergoing Endovascular Lower Extremity Revascularization.
Ramkumar N, Suckow BD, Brown JR, Sedrakyan A, MacKenzie T, Stone DH, Cronenwett JL, Goodney PP
J Am Heart Assoc. 2019 Sep 3;8(17):e013088. doi: 10.1161/JAHA.119.013088. Epub 2019 Aug 31.
PMID: 31475624

Galectin-3 as a Predictor of Long-term Survival After Isolated Coronary Artery Bypass Grafting Surgery.
Parker DM, Owens SL, Ramkumar N, Likosky D, DiScipio AW, Malenka DJ, MacKenzie TA, Brown JR
Ann Thorac Surg. 2019 Jul 20; pii: S0003-4975(19)31038-0. doi: 10.1016/j.athoracsur.2019.05.072. Epub 2019 Jul 20.
PMID: 31336070

Biomarkers improve prediction of 30-day unplanned readmission or mortality after paediatric congenital heart surgery.
Brown JR, Stabler ME, Parker DM, Vricella L, Pasquali S, Leyenaar JK, Bohm AR, MacKenzie T, Parikh C, Jacobs ML, Jacobs JP, Everett AD
Cardiol Young. 2019 Aug;29(8):1051-1056. doi: 10.1017/S1047951119001471. Epub 2019 Jul 10.
PMID: 31290383

Cardiac Biomarkers Predict Long-term Survival After Cardiac Surgery.
Ramkumar N, Jacobs JP, Berman RB, Parker DM, MacKenzie TA, Likosky DS, DiScipio A, Malenka DJ, Brown JR
Ann Thorac Surg. 2019 Dec;108(6):1776-1782. doi: 10.1016/j.athoracsur.2019.04.123. Epub 2019 Jun 27.
PMID: 31255614

Multicenter, Open-Label, Phase II Study of Bendamustine and Rituximab Followed by 90-Yttrium (Y) Ibritumomab Tiuxetan for Untreated Follicular Lymphoma (Fol-BRITe).
Lansigan F, Costa CA, Zaki BI, Yen SP, Winer ES, Ryan H, Findley D, Metzler SR, Shaw L, Toaso B, MacKenzie TA, Chen Y, Beaven AW
Clin Cancer Res. 2019 Oct 15;25(20):6073-6079. doi: 10.1158/1078-0432.CCR-18-3755. Epub 2019 Jun 26.
PMID: 31243122

Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth.
Antosca KM, Chernikova DA, Price CE, Ruoff KL, Li K, Guill MF, Sontag NR, Morrison HG, Hao S, Drumm ML, MacKenzie TA, Dorman DB, Feenan LM, Williams MA, Dessaint J, Yuan IH, Aldrich BJ, Moulton LA, Ting L, Martinez-Del Campo A, Stewart EJ, Karagas MR, O'Toole GA, Madan JC
J Bacteriol. 2019 Aug 15;201(16) pii: e00274-19. doi: 10.1128/JB.00274-19. Epub 2019 Jul 24.
PMID: 31209076

The impact of frequent cystoscopy on surgical care and cancer outcomes among patients with low-risk, non-muscle-invasive bladder cancer.
Schroeck FR, Lynch KE, Li Z, MacKenzie TA, Han DS, Seigne JD, Robertson DJ, Sirovich B, Goodney PP
Cancer. 2019 Sep 15;125(18):3147-3154. doi: 10.1002/cncr.32185. Epub 2019 May 23.
PMID: 31120559

Influence of child-targeted fast food TV advertising exposure on fast food intake: A longitudinal study of preschool-age children.
Emond JA, Longacre MR, Drake KM, Titus LJ, Hendricks K, MacKenzie T, Harris JL, Carroll JE, Cleveland LP, Gaynor K, Dalton MA
Appetite. 2019 Sep 1;140:134-141. doi: 10.1016/j.appet.2019.05.012. Epub 2019 May 9.
PMID: 31078700

Middle-aged death and taxes in the USA: Association of state tax burden and expenditures in 2005 with survival from 2006 to 2015.
MacKenzie TA, Houle J, Jiang S, Onega T
PLoS One. 2019;14(4):e0214463. doi: 10.1371/journal.pone.0214463. Epub 2019 Apr 12.
PMID: 30978199

View more publications on PubMed