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Todd A MacKenzie, PhD

Professor of Biomedical Data Science
Professor of Medicine
Professor of The Dartmouth Institute

Biomedical Data Science
The Dartmouth Institute

PhD (Statistics), McGill University, 1997
MSc (Statistics), McGill University, 1993
BSc, Dalhousie University, 1990

Norris Cotton Cancer Center
Quantitative Biomedical Sciences
The Dartmouth Institute for Health Policy and Clinical Practice


Contact Information:

Section of Clinical Research, HB 7505
One Medical Center Drive
Dartmouth Hitchcock Medical Center
Lebanon NH 03756

Phone: 603-653-3542
Fax: 603-653-3554

Professional Interests:

I use statistics to facilitate clinical and health services research across a spectrum of disciplines and specialties. This work has been reported in over 250 publications. The majority of these projects involve comparative effectiveness, clinical trials, association studies, and prediction modeling. I am especially interested in survival (aka, time-to-event) analysis, and causal inference. Recently I have been studying the association of government spending with reduced mortality in order to help explain the stagnation of American longevity.

Courses Taught:

QBS 121: Biostatistics II; a course in statistical modelling (Winter) with Tor Tosteson

QBS Biostatistics Consulting

Past Teaching:
PH 271 (TDI) "Practice of Statistics in Medicine" with James O'Malley: This course was aimed at junior faculty, post-doctoral fellows and PhD students.

PH 147 (TDI) "Advanced Methods in Health Services Research" with Tracy Onega

PEMM 107 "Biostatistics" : A course in biostatistics I developed for bench and translational scientists in molecular medicine.

Selected Publications:


DAR-901 vaccine for the prevention of infection with Mycobacterium tuberculosis among BCG-immunized adolescents in Tanzania: A randomized controlled, double-blind phase 2b trial.
Munseri P, Said J, Amour M, Magohe A, Matee M, Rees CA, Mackenzie T, Tvaroha S, Bailey-Kellogg C, Maro I, Wieland-Alter W, Adams LV, Horsburgh CR, Nakamura K, Arbeit RD, Pallangyo K, von Reyn CF
Vaccine. 2020 Oct 27;38(46):7239-7245. doi: 10.1016/j.vaccine.2020.09.055. Epub 2020 Sep 29.
PMID: 33004239

Summarizing causal differences in survival curves in the presence of unmeasured confounding.
Martinez-Camblor P, MacKenzie TA, Staiger DO, Goodney PP, O'Malley AJ
Int J Biostat. 2020 Sep 15; pii: /j/ijb.ahead-of-print/ijb-2019-0146/ijb-2019-0146.xml. doi: 10.1515/ijb-2019-0146. Epub 2020 Sep 15.
PMID: 32946418

A Community-Based Feasibility Study of Weight-Loss in Rural, Older Adults with Obesity.
Batsis JA, Petersen CL, Cook SB, Al-Nimr RI, Pidgeon D, Mackenzie TA, Bartels SJ
J Nutr Gerontol Geriatr. 2020 Sep 9;:1-13. doi: 10.1080/21551197.2020.1817226. Epub 2020 Sep 9.
PMID: 32907522

Predicting colorectal polyp recurrence using time-to-event analysis of medical records.
Harrington LX, Wei JW, Suriawinata AA, Mackenzie TA, Hassanpour S
AMIA Jt Summits Transl Sci Proc. 2020;2020:211-220. Epub 2020 May 30.
PMID: 32477640

A Weight-Loss Intervention Augmented by a Wearable Device in Rural Older Adults with Obesity: A Feasibility Study.
Batsis JA, Petersen CL, Clark MM, Cook SB, Lopez-Jimenez F, Al-Nimr RI, Pidgeon D, Kotz D, Mackenzie TA, Bartels SJ
J Gerontol A Biol Sci Med Sci. 2020 May 8; pii: glaa115. doi: 10.1093/gerona/glaa115. Epub 2020 May 8.
PMID: 32384144

Patterns in continuous pulse oximetry data prior to pulseless electrical activity arrest in the general care setting.
McGrath SP, Perreard IM, MacKenzie T, Blike GT
J Clin Monit Comput. 2020 Apr 8; doi: 10.1007/s10877-020-00509-8. Epub 2020 Apr 8.
PMID: 32270344

Reported Weight Change in Older Adults and Presence of Frailty.
Crow RS, Petersen CL, Cook SB, Stevens CJ, Titus AJ, Mackenzie TA, Batsis JA
J Frailty Aging. 2020;9(2):74-81. doi: 10.14283/jfa.2019.44.
PMID: 32259180

The impact of low- versus high-intensity surveillance cystoscopy on surgical care and cancer outcomes in patients with high-risk non-muscle-invasive bladder cancer (NMIBC).
Rezaee ME, Lynch KE, Li Z, MacKenzie TA, Seigne JD, Robertson DJ, Sirovich B, Goodney PP, Schroeck FR
PLoS One. 2020;15(3):e0230417. doi: 10.1371/journal.pone.0230417. Epub 2020 Mar 23.
PMID: 32203532

Effects of Blended (Yellow) vs Forced Coagulation (Blue) Currents on Adverse Events, Complete Resection, or Polyp Recurrence After Polypectomy in a Large Randomized Trial.
Pohl H, Grimm IS, Moyer MT, Hasan MK, Pleskow D, Elmunzer BJ, Khashab MA, Sanaei O, Al-Kawas FH, Gordon SR, Mathew A, Levenick JM, Aslanian HR, Antaki F, von Renteln D, Crockett SD, Rastogi A, Gill JA, Law RJ, Elias PA, Pellise M, Mackenzie TA, Rex DK
Gastroenterology. 2020 Jul;159(1):119-128.e2. doi: 10.1053/j.gastro.2020.03.014. Epub 2020 Mar 12.
PMID: 32173478

Association of Sex With Repair Type and Long-term Mortality in Adults With Abdominal Aortic Aneurysm.
Ramkumar N, Suckow BD, Arya S, Sedrakyan A, Mackenzie TA, Goodney PP, Brown JR
JAMA Netw Open. 2020 Feb 5;3(2):e1921240. doi: 10.1001/jamanetworkopen.2019.21240. Epub 2020 Feb 5.
PMID: 32058556

View more publications on PubMed