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Todd A MacKenzie, PhD

Professor of Biomedical Data Science
Professor of Medicine
Professor of The Dartmouth Institute

Biomedical Data Science
The Dartmouth Institute

PhD (Statistics), McGill University, 1997
MSc (Statistics), McGill University, 1993
BSc, Dalhousie University, 1990

Dartmouth Cancer Center
Quantitative Biomedical Sciences
The Dartmouth Institute for Health Policy and Clinical Practice


Academic Analytics
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Contact Information

Section of Clinical Research, HB 7505
One Medical Center Drive
Dartmouth Hitchcock Medical Center
Lebanon NH 03756

Phone: 603-653-3542
Fax: 603-653-3554
Email: Todd.A.MacKenzie@Dartmouth.edu

Professional Interests

I use statistics to facilitate clinical and health services research across a spectrum of disciplines and specialties. This work has been reported in over 300 publications. The majority of these projects involve comparative effectiveness, clinical trials, association studies, and prediction modeling. I am especially interested in survival (aka, time-to-event) analysis, and causal inference. Recent work includes studying the quality and effectiveness of colonoscopy for colorectal screening and surveillance.

Courses Taught

QBS 121: Biostatistics II; a course in statistical modelling (Winter) with Tor Tosteson

QBS 123: Biostatistics Consulting

Past Teaching:
PH 271 (TDI) "Practice of Statistics in Medicine" with James O'Malley: This course was aimed at junior faculty, post-doctoral fellows and PhD students.

PH 147 (TDI) "Advanced Methods in Health Services Research" with Tracy Onega

PEMM 107 "Biostatistics" : A course in biostatistics I developed for bench and translational scientists in molecular medicine.

Selected Publications


Response to commentary on "Automated classification of fat-infiltrated axillary lymph nodes on screening mammograms".
Song Q, diFlorio-Alexander RM, Sieberg RT, Dwan D, Boyce W, Stumetz K, Patel SD, Karagas MR, Mackenzie TA, Hassanpour S
Br J Radiol. 2023 Dec 28; pii: tqad062. doi: 10.1093/bjr/tqad062. Epub 2023 Dec 28.
PMID: 38306449

Why Are We Weighting? Understanding the Estimates From Propensity Score Weighting and Matching Methods.
Ramkumar N, Iribarne A, Olmstead EM, Malenka DJ, Mackenzie TA
Circ Cardiovasc Qual Outcomes. 2024 Jan;17(1):e007803. doi: 10.1161/CIRCOUTCOMES.120.007803. Epub 2024 Jan 8.
PMID: 38189126

Fukutani KF, Hampton TH, Bobak CA, MacKenzie TA, Stanton BA
Pac Symp Biocomput. 2024;29:534-548.
PMID: 38160305

Relationship Between Tobacco Product Use and Health-Related Quality of Life Among Individuals With COPD in Waves 1-5 (2013-2019) of the Population Assessment of Tobacco and Health Study.
Paulin LM, Halenar MJ, Edwards KC, Lauten K, Taylor K, Brunette M, Tanski S, MacKenzie T, Stanton CA, Hatsukami D, Hyland A, Mahoney MC, Niaura R, Trinidad D, Blanco C, Compton W, Gardner LD, Kimmel HL, Cummings KM, Lauterstein D, Roh EJ, Marshall D, Sargent JD
Chronic Obstr Pulm Dis. 2024 Jan 25;11(1):68-82. doi: 10.15326/jcopdf.2023.0422.
PMID: 38113525

Endoscopist Adenoma Per Colonoscopy Detection Rates and Risk for Post Colonoscopy Colorectal Cancer: Data From New Hampshire Colonoscopy Registry.
Anderson JC, Rex DK, Mackenzie TA, Hisey W, Robinson CM, Butterly LF
Gastrointest Endosc. 2023 Nov 20; pii: S0016-5107(23)03090-0. doi: 10.1016/j.gie.2023.11.014. Epub 2023 Nov 20.
PMID: 37993057

Automated classification of fat-infiltrated axillary lymph nodes on screening mammograms.
Song Q, diFlorio-Alexander RM, Sieberg RT, Dwan D, Boyce W, Stumetz K, Patel SD, Karagas MR, MacKenzie TA, Hassanpour S
Br J Radiol. 2023 Nov;96(1151):20220835. doi: 10.1259/bjr.20220835. Epub 2023 Sep 26.
PMID: 37751215

Novel integration of governmental data sources using machine learning to identify super-utilization among U.S. counties.
Ricket IM, Matheny ME, MacKenzie TA, Emond JA, Ailawadi KL, Brown JR
Intell Based Med. 2023;7 pii: 100093. doi: 10.1016/j.ibmed.2023.100093. Epub 2023 Jan 21.
PMID: 37476591

Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk.
Luyapan J, Bosse Y, Li Z, Xiao X, Rosenberger A, Hung RJ, Lam S, Zienolddiny S, Liu G, Kiemeney LA, Chen C, McKay J, Johansson M, Johansson M, Tardon A, Fernandez-Tardon G, Brennan P, Field JK, Davies MP, Woll PJ, Cox A, Taylor F, Arnold SM, Lazarus P, Grankvist K, Landi MT, Christiani DC, MacKenzie TA, Amos CI
Hum Mol Genet. 2023 Sep 5;32(18):2842-2855. doi: 10.1093/hmg/ddad095.
PMID: 37471639

Sex differences in outcomes among adults undergoing abdominal aortic aneurysm repair.
Ramkumar N, Suckow BD, Columbo JA, Arya S, Sedrakyan A, Mackenzie TA, Brown JR, Goodney PP
J Vasc Surg. 2023 Nov;78(5):1212-1220.e5. doi: 10.1016/j.jvs.2023.06.105. Epub 2023 Jul 12.
PMID: 37442215

The association between cervical artery dissection and spinal manipulation among US adults.
Whedon JM, Petersen CL, Schoellkopf WJ, Haldeman S, MacKenzie TA, Lurie JD
Eur Spine J. 2023 Oct;32(10):3497-3504. doi: 10.1007/s00586-023-07844-9. Epub 2023 Jul 8.
PMID: 37422607

View more publications on PubMed