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Todd A MacKenzie, PhD

Title(s):
Professor of Biomedical Data Science
Professor of Medicine
Professor of The Dartmouth Institute

Additional Titles/Positions/Affiliations:
Director of Master's Degree in Health Data Science

Department(s):
Biomedical Data Science
Medicine
The Dartmouth Institute

Education:
PhD (Statistics), McGill University, 1997
MSc (Statistics), McGill University, 1993
BSc, Dalhousie University, 1990

Programs:
Norris Cotton Cancer Center
Quantitative Biomedical Sciences
SYNERGY
The Dartmouth Institute for Health Policy and Clinical Practice

Websites:
http://scholar.google.com/citations?user=jwW_WhMAAAAJ&hl=en

http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47889830/?sort=date&direction=descending

Contact Information:

Section of Clinical Research, HB 7505
One Medical Center Drive
Dartmouth Hitchcock Medical Center
Lebanon NH 03756

Phone: 603-653-3542
Fax: 603-653-3554
Email: Todd.A.MacKenzie@Dartmouth.edu


Professional Interests:

I use data science to help clinical and health services researchers from a vast spectrum of disciplines and specialties. The majority of these projects involve comparative effectiveness, clinical trials, association studies and prediction modeling. I am especially interested in survival (aka, time-to-event) analysis and causal inference.



Courses Taught:

QBS "Foundations in Biostatistics II" (Winter) with Tor Tosteson

PHAR 602 "Clinical Investigation" (Winter): A short course in clinical research for MD-PhD students.



Past Teaching:
PH 271 (TDI) "Practice of Statistics in Medicine" with James O'Malley: This course is aimed at junior faculty, post-doctoral fellows and PhD students.


ECS 147 (TDI) "Advanced Methods in Health Services Research" with Tracy Onega

PEMM 107 "Biostatistics" : A course in biostatistics I developed for bench and translational scientists in molecular medicine.


Selected Publications:

 

Galectin-3 as a Predictor of Long-term Survival after Isolated Coronary Artery Bypass Grafting Surgery.
Parker DM, Owens SL, Ramkumar N, Likosky D, DiScipio AW, Malenka DJ, MacKenzie TA, Brown JR
Ann Thorac Surg. 2019 Jul 20; pii: S0003-4975(19)31038-0. doi: 10.1016/j.athoracsur.2019.05.072. Epub 2019 Jul 20.
PMID: 31336070

Biomarkers improve prediction of 30-day unplanned readmission or mortality after paediatric congenital heart surgery.
Brown JR, Stabler ME, Parker DM, Vricella L, Pasquali S, Leyenaar JK, Bohm AR, MacKenzie T, Parikh C, Jacobs ML, Jacobs JP, Everett AD
Cardiol Young. 2019 Jul 10;:1-6. doi: 10.1017/S1047951119001471. Epub 2019 Jul 10.
PMID: 31290383

Cardiac Biomarkers Predict Long-Term Survival After Cardiac Surgery.
Ramkumar N, Jacobs JP, Berman RB, Parker DM, MacKenzie TA, Likosky DS, DiScipio A, Malenka DJ, Brown JR
Ann Thorac Surg. 2019 Jun 27; pii: S0003-4975(19)30893-8. doi: 10.1016/j.athoracsur.2019.04.123. Epub 2019 Jun 27.
PMID: 31255614

Multicenter, Open Label, Phase II Study of Bendamustine and Rituximab followed by 90-yttrium (Y) Ibritumomab Tiuxetan for Untreated Follicular Lymphoma (Fol-BRITe).
Lansigan F, Costa CA, Zaki B, Yen S, Winer EP, Ryan H, Findley D, Metzler S, Shaw L, Toaso B, Mackenzie TA, Chen Y, Beaven AW
Clin Cancer Res. 2019 Jun 26; pii: clincanres.3755.2018. doi: 10.1158/1078-0432.CCR-18-3755. Epub 2019 Jun 26.
PMID: 31243122

Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth.
Antosca KM, Chernikova DA, Price CE, Ruoff KL, Li K, Guill MF, Sontag NR, Morrison HG, Hao S, Drumm ML, MacKenzie TA, Dorman DB, Feenan LM, Williams MA, Dessaint J, Yuan IH, Aldrich BJ, Moulton LA, Ting L, Martinez-Del Campo A, Stewart EJ, Karagas MR, O'Toole GA, Madan JC
J Bacteriol. 2019 Aug 15;201(16) pii: e00274-19. doi: 10.1128/JB.00274-19. Epub 2019 Jul 24.
PMID: 31209076

The impact of frequent cystoscopy on surgical care and cancer outcomes among patients with low-risk, non-muscle-invasive bladder cancer.
Schroeck FR, Lynch KE, Li Z, MacKenzie TA, Han DS, Seigne JD, Robertson DJ, Sirovich B, Goodney PP
Cancer. 2019 May 23; doi: 10.1002/cncr.32185. Epub 2019 May 23.
PMID: 31120559

Influence of child-targeted fast food TV advertising exposure on fast food intake: A longitudinal study of preschool-age children.
Emond JA, Longacre MR, Drake KM, Titus LJ, Hendricks K, MacKenzie T, Harris JL, Carroll JE, Cleveland LP, Gaynor K, Dalton MA
Appetite. 2019 Sep 1;140:134-141. doi: 10.1016/j.appet.2019.05.012. Epub 2019 May 9.
PMID: 31078700

Middle-aged death and taxes in the USA: Association of state tax burden and expenditures in 2005 with survival from 2006 to 2015.
MacKenzie TA, Houle J, Jiang S, Onega T
PLoS One. 2019;14(4):e0214463. doi: 10.1371/journal.pone.0214463. Epub 2019 Apr 12.
PMID: 30978199

Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial.
Pohl H, Grimm IS, Moyer MT, Hasan MK, Pleskow D, Elmunzer BJ, Khashab MA, Sanaei O, Al-Kawas FH, Gordon SR, Mathew A, Levenick JM, Aslanian HR, Antaki F, von Renteln D, Crockett SD, Rastogi A, Gill JA, Law RJ, Elias PA, Pellise M, Wallace MB, Mackenzie TA, Rex DK
Gastroenterology. 2019 Mar 15; pii: S0016-5085(19)33573-5. doi: 10.1053/j.gastro.2019.03.019. Epub 2019 Mar 15.
PMID: 30885778

Association of Obesity and Frailty in Older Adults: NHANES 1999-2004.
Crow RS, Lohman MC, Titus AJ, Cook SB, Bruce ML, Mackenzie TA, Bartels SJ, Batsis JA
J Nutr Health Aging. 2019;23(2):138-144. doi: 10.1007/s12603-018-1138-x.
PMID: 30697622

View more publications on PubMed