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Todd A MacKenzie, PhD

Title(s)
Professor of Biomedical Data Science
Professor of Medicine
Professor of The Dartmouth Institute

Department(s)
Biomedical Data Science
Medicine
The Dartmouth Institute

Education
PhD (Statistics), McGill University, 1997
MSc (Statistics), McGill University, 1993
BSc, Dalhousie University, 1990

Programs
Dartmouth Cancer Center
Quantitative Biomedical Sciences
The Dartmouth Institute for Health Policy and Clinical Practice

Websites
http://scholar.google.com/citations?user=jwW_WhMAAAAJ&hl=en


Contact Information

Section of Clinical Research, HB 7505
One Medical Center Drive
Dartmouth Hitchcock Medical Center
Lebanon NH 03756

Phone: 603-653-3542
Fax: 603-653-3554
Email: Todd.A.MacKenzie@Dartmouth.edu


Professional Interests

I use statistics to facilitate clinical and health services research across a spectrum of disciplines and specialties. This work has been reported in over 300 publications. The majority of these projects involve comparative effectiveness, clinical trials, association studies, and prediction modeling. I am especially interested in survival (aka, time-to-event) analysis, and causal inference. Recent work includes studying the quality and effectiveness of colonoscopy for colorectal cancer screening and surveillance.



Courses Taught

QBS 121: Biostatistics II; a course in statistical modelling (Winter) with Tor Tosteson

QBS 123: Biostatistics Consulting

Past Teaching:
PH 271 (TDI) "Practice of Statistics in Medicine" with James O'Malley: This course was aimed at junior faculty, post-doctoral fellows and PhD students.


PH 147 (TDI) "Advanced Methods in Health Services Research" with Tracy Onega

PEMM 107 "Biostatistics" : A course in biostatistics I developed for bench and translational scientists in molecular medicine.


Selected Publications

 

Kidney Failure in Persons With Cystic Fibrosis.
Stevanovic M, MacKenzie TA, Zimmerman AM, Graber ML
Kidney Med. 2026 May;8(5):101263. doi: 10.1016/j.xkme.2026.101263. Epub 2026 Jan 13.
PMID: 41971683

Association between index adenomas and advanced findings at third colonoscopy: Data from the New Hampshire Colonoscopy Registry.
Javidi D, Dairi O, MacKenzie TA, Amos CI, Butterly LF, Anderson JC
Clin Gastroenterol Hepatol. 2026 Mar 27; pii: S1542-3565(26)00224-7. doi: 10.1016/j.cgh.2026.03.018. Epub 2026 Mar 27.
PMID: 41905521

Bridging evidence and practice: implementation science and bundled care strategies for fluid management in critically ill neonates.
Pak AC, Neyra JA, Brown JR, Travers CP, Starr MC, Harer MW, Sullivan I, MacKenzie TA, Colicchio TK, Griffin R, Askenazi DJ
Front Med (Lausanne). 2026;13:1706165. doi: 10.3389/fmed.2026.1706165. Epub 2026 Feb 25.
PMID: 41822900

Outcomes of Kidney Transplantation in Cystic Fibrosis.
Stevanovic M, MacKenzie TA, Zimmerman AM, Graber ML
Transplant Proc. 2026 Apr;58(3):429-435. doi: 10.1016/j.transproceed.2026.02.025. Epub 2026 Mar 5.
PMID: 41791970

Heterogeneity in Treatment Outcomes After a Multicomponent Weight Loss Intervention in Older Adults with Obesity.
Gavras A, Memili A, Lynch DH, Spangler HB, Cook SB, Mackenzie TA, Gross DC, Batsis JA
Curr Dev Nutr. 2026 Feb;10(2):107649. doi: 10.1016/j.cdnut.2026.107649. Epub 2026 Jan 28.
PMID: 41726778

Risk Factors of Proximal and Distal Advanced Colorectal Conventional and Serrated Neoplasia in Adults Younger Than 50 Years of Age.
Javidi DJ, Butterly LF, Amos CI, Mackenzie TA, Robinson CM, Anderson JC
Am J Gastroenterol. 2026 Feb 12; doi: 10.14309/ajg.0000000000003950. Epub 2026 Feb 12.
PMID: 41677132

Assessing the Impact of Supplemental Oxygen Use on Deterioration Detection in the General Care Setting With Pulse Oximetry-Based Continuous Monitoring.
McGrath SP, Perreard IM, Blike GT, McGovern KM, Xia X, MacKenzie T
J Clin Nurs. 2026 Feb 5; doi: 10.1111/jocn.70236. Epub 2026 Feb 5.
PMID: 41645560

Higher Sessile Serrated Lesion Detection Rates Calculated Using All Examinations Are Associated With Lower Risk for Postcolonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry.
Hagen R, Rex DK, MacKenzie TA, Amos CI, Butterly LF, Anderson JC
Clin Transl Gastroenterol. 2026 Jan 30; doi: 10.14309/ctg.0000000000000987. Epub 2026 Jan 30.
PMID: 41614701

Single nuclei and spatial profiling of sacrococcygeal teratomas reveals cellular composition and X inactivation heterogeneity.
Rojas EJ, Giannikou K, Huang BJ, Cho SJ, Cordero MA, Pena D, Vu L, Bagrodia A, Derderian SC, MacKenzie TC, Laird DJ
NPJ Precis Oncol. 2026 Jan 21;10(1) doi: 10.1038/s41698-025-01262-4. Epub 2026 Jan 21.
PMID: 41565739

Association Between Serrated Polyps on Index Examination and Advanced Findings Detected on the Second Surveillance Colonoscopy: Data From the New Hampshire Colonoscopy Registry.
Dairi O, Anderson JC, Amos CI, Hisey W, Mackenzie TA, Butterly LF, Cancer Intervention And Surveillance Modeling Network/New Hampshire Colonoscopy Registry Working Group
Gastroenterology. 2026 Jan 19; pii: S0016-5085(25)06583-7. doi: 10.1053/j.gastro.2025.11.023. Epub 2026 Jan 19.
PMID: 41553308

View more publications on PubMed