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James T. DeVries, MD

Contact Information

Professional Interests

Cardiac catheterization and coronary intervention
Transcatheter aortic valve replacement (TAVR)
aortic and mitral valvular heart disease
Peripheral artery intervention
Stroke and catheter based intervention for acute stroke
pulmonary embolism therapies
Device technology for cardiac monitoring

Rotations and Thesis Projects

CLINICAL TRIALS:
1. VEST trial. 2019-2020. Sub-investigator. CSTN-sponsored trial of external mechanical scaffold for CABG grafts to evaluate long-term patency of saphenous vein grafts.
2. Safe-STemi trial. 2018-present. Sub-investigator. Medtronic-sponsored trial of radial access combined with non-culprit PCI in STEMI.
3. EARLY TAVR Trial. 2018-present. Site co-PI. Edwards-sponsored trial of immediate TAVR versus clinical surveillance for asymptomatic severe aortic stenosis.
4. ISCHEMIA – CKD Trial. NYU School of Medicine/NIH funded. Sub Investigator June 2016-present. International Study of Comparative Health Effectiveness with Medical and Invasive Approaches.
5. Edwards LifeSciences/PARTNER 3 Valve in Valve. January 17-present. Co-PI. Investigate the safety and effectiveness of SAPIEN 3 trans-catheter heart valve implantation in patients with a failing aortic bioprosthetic valve.
6. Phillips Volcano/DEFINE PCI. June 2017-present. Sub Investigator. Physiologic assessment of coronary stenosis following PCI.
7. Boston Scientific/ Evolve Short DAPT Synergy Registry May 2016-presnt. PI. Use of the Synergy stent in patients at high risk for bleeding with 3 months of DAPT.
8. Edwards LifeScience/PARTNER III. July 2016-present. Co-PI. TAVR versus SAVR in low risk patients with severe aortic stenosis.
9. BEST-CLI Trial- February 2015- present. Co-PI. Randomized trial of endovascular versus surgical revascularization for critical limb ischemia (CLI).
10. ABSORB Trial (II-IV)- October 2013-2017. Sub PI. Abbott-sponsored trial of bioabsorbable stent for de novo coronary lesions.
11. Tryton Side Branch Study IDE/Registry April 2011-2015. PI. Use of a novel dedicated side branch stent in complex coronary bifurcation lesions. Original randomized trial and follow up registry.
12. Edwards LifeScience / PARTNER II August 2011-ongoing. Co-PI. Percutaneous aortic valve replacement with the Edwards Sapien bioprosthetic aortic valve in patients who are not candidates for surgical AVR (cohort B), high risk and intermediate risk patients.
13. Gilead/ RIVER-PCI December 2011-2015. PI. Trial using ranolazine to modulate anginal status following PCI.
14. Cordis / CYPRESS March 10, 2010-2013. Sub-PI. A Prospective, Randomized, Multi-Center, Double-Blind Trial to Assess the Effectiveness and Safety of Different Durations of Dual Anti-Platelet Therapy (DAPT) in Subjects Undergoing Percutaneous Coronary Intervention with the CYPHER® Sirolimus-eluting Coronary Stent (CYPHER® Stent).
15. Volcano/ FIRST October 2010-2013. PI. Fractional Flow Reserve and Intravascular Ultrasound Relationship Study. Assessment of intermediate coronary lesions with FFR and IVUS.
16. Medtronic / RESOLUTE March 19, 2009-2013. Sub-PI. A Clinical Evaluation of the Medtronic Endeavor® Resolute Zotarolimus-Eluting Coronary Stent System in the Treatment of De Novo Lesions in Native Coronary Arteries with a Reference Vessel Diameter of 2.25 mm to 4.2 mm.
17. Accumetrics / GRAVITAS August 14, 2008-2010. Sub-PI. Gauging Responsiveness with A VerifyNow assay-Impact on Thrombosis And Safety.
18. BridgePoint Medical / FAST-CTOs August 19, 2009-July 2010. Sub-PI. Facilitated Antegrade Steering Technique in Chronic Total Occlusions Clinical Study.
19. Abiomed / PROTECT II September 30, 2008-March 11, 2010. Sub-PI. A prospective, multi-center, randomized controlled trial of the IMPELLA® RECOVER® LP 2.5 System versus Intra Aortic Balloon Pump (IABP) in Patients Undergoing Non Emergent High Risk PCI.
20. Abbott Vascular / SPIRIT IV February 12, 2007-July 30, 2008. Sub-PI. A Clinical Evaluation of the XIENCE™ V Everolimus Eluting Coronary Stent System (EECSS) in the Treatment of Subjects with de novo Native Coronary Artery Lesions.

Grant Information

National Science Foundation award 1418497, Kofi Odame, PhD and Ryan Halter PhD co-PI. $829,000 funding August 2014-August 2017. A non-invasive cardiac output device for telemonitoring. Development of a wearable imaging belt using electrical impedance tomography (EIT) to measure cardiac output

Courses Taught

Introduction to the Catheterization Lab clinical rotation
SBM Cardiology small group leader
On doctoring student Mentor

Biography

Book Chapters:
1. DeVries,JT, Kaplan,AV, Thompson,CA. "Coronary Bifurcation Lesions", Textbook of Cardiovascular Intervention, (pp. 10), 2014, Springer.
2. DeVries,JT, Thompson,CA. "Acute Stroke Intervention" Textbook of Cardiovascular Intervention,. (Ed.), 2014, Springer.
3. DeVries,JT "Complications of Cardiac Catheterization”, Vascular Emergencies: Expert Management for the Emergency Physician. Rogers, RL, Scalea,T. (Eds.), May 2013, Cambridge University Press.

Publications:
1. Chaudry, H, Lee, J, Li, Shawn, Gasperetti, A, Lee, K, Zbib, N, Amakiri, I, Andrus, B, DeVries, JT. Sex differences in acute bleeding and vascular complications following percutaneous coronary intervention between 2003 and 2016: Trends from the Dartmouth Dynamic Registry. Cardiovascular Revascularization Medicine, 1553-8389 (20), July 2020.

2. Lahoud, R, Butzel, D, Parsee, A, Huang, Y, Solomon, JT, DeVries, JT, Flynn, JM, Iribarne, A, Lee, PV, Ross, C, Malenka, DJ, Dauerman, HL. Acute Kidney Recovery in Patients who underwent Transcatheter versus Surgical Aortic Valve Replacement (from the Northern New England Cardiovascular Study Group). American Journal of Cardiology. 2020, March 1; 125(5):788-794.

3. Azarbal, A, Malenka, DJ, Huang, YL, Ross, CS, Solomon, RJ, DeVries, JT, Flynn, JM, Butzel, D, McKay, M, Dauerman, HL. Recovery of kidney dysfunction after transcatheter aortic valve implantation (from the Northern New England Cardiovascular Disease Study Group). America Journal of Cardiology. 2019: Feb 123(3): 426-433.

4. Frampton, J, DeVries JT, Welch, TD, and Gersh, BJ. Modern management of ST elevation myocardial infarction. Curr Prob Cardiology. 2018 Sept 14; epub ahead of print.

5. Li, SX, Chaudry, HI, Lee, J, Curran, TB, Kumar,V, Wong,KK, Andrus, BW, DeVries, JT. Patterns of In-Hospital Mortality and Bleeding Complications Following PCI for Very Elderly Patients. J. Geriatric Cardiology. 2018:Feb, 15(2):131-136.

6. Chaudry, HI, Curran, TB, Andrus, BW, Conley, SM, DeVries, JT. Bivalirudin versus Heparin, without Glycoprotein Inhibition, in Percutaneous Coronary Intervention: A Comparison of Ischemic and Hemorrhagic Outcomes over 10 years. Cardiovascular Revascularization Medicine. 2018, 19(3b), 338-342.

7. Smits NC, Kobayashi T, Srivastava PK, Skopelja S, Ivy JA, Elwood DJ, Stan RV, Tsongalis GJ, Sellke FW, Gross PL, Cole MD, DeVries JT, Kaplan AV, Robb JF, Williams SM, Shworak NW. HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis. Matrix Biol. 2017 Nov, 63:69-90. Epub 2017 Jan 23.

8. Buss NI, Friedman SE, Andrus BW, DeVries JT. Warfarin for Stroke Prevention Following Anterior ST-Elevation Myocardial Infarction. Coronary Artery Dis. 2013 Dec; 24(8): 636-41.

9. Waksman R, Legutko J, Singh J, Orlando Q, Marso S, Schloss T, Tugaoen J, DeVries JT, Palmer N, Haude M, Swymelar S, Torguson R. FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study. J Am Coll Cardiol. 2013 Mar 5; 61(9): 917-23.

10. Montgomery, K., Ortved, K., DeVries, J., Hackett, R., Kern, T., Irby, N. Bilateral Parotid Duct Transposition for Keratoconjunctivis Sicca in a Connemara Stallion. 2012 American College of Veterinary Ophthalmologists. Vet Ophthalmol. 2012 Oct 15: 1-9.

11. Leung, CC, Ball, TC, Sidhu, MS, DeVries, JT, Jayne, JE, Robb, JF, Kaplan, AV, Brown, JR, Malenka, DJ, Thompson, CA. Real world application of stenting of unprotected left main coronary stenosis: A single-center experience. Cardiol Res. 2012 Jun 3(3); 100-108.

12. Robert A, Brown J, Sidhu M, Ramanath V, DeVries JT, Jayne J, Hettleman B, Friedman B, Niles N 2nd, Kaplan A, Malenka D, Robb J, Thompson C (for the Dartmouth Dynamic Registry Investigators). The Evaluation of Creatinine Clearance, Estimated Glomerular Filtration Rate and Serum Creatinine in Predicting Contrast-induced Acute Kidney Injury among Patients Undergoing Percutaneous Coronary Intervention. Cardiovasc Revasc Med. 2012 Jan; 13(1): 3-10. Epub 2011 Nov 16. PubMed PMID: 22093591.
13. Steiner J, Dhingra R, DeVries JT. Needle in the Haystack: Purulent Pericarditis from Injection Drug Use. Catheter Cardiovasc Interv. 2011 Jul 29. DOI: 10.1002/ccd.23259.
14. Ramanath V., Brown J., Malenka D., DeVries JT., Sidhu M., Robb J., Jayne J., Hettleman B., Friedman B., Niles N. 2nd, Kaplan A., Thompson C. (for the Dartmouth Dynamic Registry Investigators). Outcomes of Diabetics Receiving Bare-metal Stents Versus Drug-eluting Stents. Catheter Cardiovasc Interv. 2010 Oct 1; 76(4): 473-481. PubMed PMID: 20882647.

15. Sidhu M., Brown J., Yang R., DeVries JT., Jayne J., Hettleman B., Friedman B., Niles N., Kaplan A., Robb J., Malenka D., Thompson C. (for the Dartmouth Dynamic Registry Investigators). Real World, Long-term Outcomes Comparison between Paclitaxel-eluting and Sirolimus-eluting Stent Platforms. J Interv Cardiol. 2010 Apr; 23(2): 167-75. Epub 2010 Mar 2. PubMed PMID: 20236213.

16. Leung C., Sabir S., Brown J., Sidhu M., Kaplan A., Jayne J., Friedman B., Hettleman B., Niles N., DeVries JT., Robb J., Malenka D., Thompson C., for the Dartmouth Dynamic Registry Investigators. The Impact of Hematocrit Drop on Long-Term Survival After Cardiac Catheterization: Insights From The Dartmouth Dynamic Registry. Catheter and Cardiovascular Intervention, 2010, 75(3): 378-86. PubMed PMID: 19937779.

17. DeVries, JT., White, C., Collins, T., Jenkins, S., Reilly, J., Grise, M., McMullan, P., Badawi, R., Ramee, S. Acute Stroke Intervention by Interventional Cardiologists. Catheterization and Cardiovascular Intervention, 2009; 73(5): 692-8.

18. Thompson, C., Sidhu, M., Brown, J., Sabir, S., Floyd, K., DeVries, J., Jayne, J., Friedman, B., Hettleman, B., Niles, N., Robb, J., Malenka, D., and Kaplan, A. (for the Dartmouth Dynamic Registry Investigators). Classification and Atherosclerosis Distribution In Patients With Left Main Coronary Disease. Journal Interventional Cardiology, 2009; 431-6.

19. DeVries, JT., White, C., Cunningham, M., Ramee, S. Catheter-Based Therapy for Acute Ischemic Stroke: A National Unmet Need. Catheterization and Cardiovascular Intervention, 2008; 72(5): 705-9.

20. Brown, J., Malenka, D., DeVries, JT., Robb, J., Jayne, J., Friedman, B., Hettleman, B., Niles, N.,Kaplan, A., Schoolwerth, A., Thompson, C. (from the Dartmouth Dynamic Registry). Transient And Persistent Renal Dysfunction Are Predictors Of Survival After Percutaneous Coronary Intervention: Insights From The Dartmouth Dynamic Registry. Catheterization and Cardiovascular Intervention, 2008; 72(3): 347-54.

21. Brown, J., DeVries, JT., Piper, W., Robb, J., Hearne, M., Ver Leee, P., Kellet, M, Watkins, M., Ryan Jr, T., Silver, T., Ross, C., MacKenzie, T., O’Connor, G., and Malenka, D (for the NNE). Serious Renal Dysfunction after Percutaneous Intervention can be predicted. American Heart Journal, 2008; 155(2): 260-266.

22. Dacey, L., Likosky, D., Ryan, T., Robb, J., Quinn, R., DeVries, JT., Hearne, M., Leavitt, B., Dunton, R., Clough, R., Sisto, D., Ross, C., Olmstead, E., O’connor, G., and Malenka, D. Long-term Survival after Surgery versus Percutaneous Intervention in Octogenarians with Multivessel Coronary Disease. Annals of Thoracic Surgery, 2007; 84: 1904-1911.

23. Malenka, D., DeVries, JT., and Shubrooks, S. Percutaneous Coronary Interventions in The Elderly: A 10 Year Experience In Northern New England. Journal of Geriatric Cardiology, 2005; 2(1): 17-22.

24. Ehmann, U., DeVries, JT., Chen, M., Adamos, A., Guzman, R., and Omary, M. An In Vitro Model Of Epithelial Growth Stimulation In The Rodent Mammary Gland. Cell Proliferation, 2003; 36: 177-190.

25. Ehmann, U., Calderwood, S., Stevenson, M., & DeVries, JT. Physical Connections between Feeder Cells and Recipient Normal Mammary Epithelial Cells. Experimental Cell Research, 1998; 243: 76-86.

26. Anderson, T., Davidovich, A., Feldman, D., Sprinkle, T., Calderon, R., Fossom, L., DeVries, G., DeVries, JT., Arezzo, J., & Brosnan, C. Mitochondrial Schwannopathy and Peripheral Myelinopathy in a Rabbit Model of Dideoxycytidine (ddC) Neurotoxicity. Laboratory Investigation, 1993; 70(5): 724-39.

27. DeVries, G., DeVries, JT., Calderon, R., Fossom, L., Sprinkle, T., & Anderson, T. Mechanism of Demyelination in a Rabbit Model of Dideoxycytidine Intoxication. Trans. Amer. Soc. Neurochem, 1993; 24: 257.