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Robert B. Santulli, MD

Honorary Associate Professor of Psychiatry

Additional Titles/Positions/Affiliations:
Visiting Associate Professor
Department of Psychological and Brain Sciences
Dartmouth College


Columbia University College of Physicians & Surgeons, MD 1973
Yale University, BA 1969

Contact Information:

Department of Psychological and Brain Sciences
HB 6207
Hanover NH 03755

Office: Dept of Psychological and Brain Sciences
Phone: 603 252-2565
Email: rbs@dartmouth.edu

Professional Interests:

Alzheimer's Disease

Grant Information:

Title: Memory Circuitry in Mild Cognitive Impairment and Early Alzheimer’s
Disease: A Functional and Morphometric MRI Study of Early Detection
And Longitudinal Change
(Also known as The Dartmouth Memory and Aging Study)
Agency: National Institute on Aging/National Institutes of Health
Amount: $1,859,806
Period: 2001-Current
Principal Investigator:
Andrew J. Saykin, Psy.D
Function: Geropsychiatric evaluation and ongoing monitoring of subjects
Medication monitoring and coordination with primary care physicians
Diagnostic and staging consensus group member
Miscellaneous other research tasks
10% Time commitment

Title: Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Agency: National Institute on Aging/National Institutes of Health; Industry
Period: 2005-2009
Investigator: Andrew Saykin, PsyD, Robert B. Santulli, M.D.
Function: Study physician for Dartmouth site:
Geropsychiatric evaluation and ongoing monitoring of subjects;
Periodic clinical and research assessments;
Miscellaneous other research tasks
5% - 10% Time commitment

Courses Taught:

Living with Cognitive Decline and Dementia (2019)
Living with Dementia (2017-2018)

Selected Publications:


Prediction and Classification of Alzheimer's Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers.
Gupta Y, Lama RK, Kwon GR, Alzheimer's Disease Neuroimaging Initiative.
Front Comput Neurosci. 2019;13:72. doi: 10.3389/fncom.2019.00072. Epub 2019 Oct 16.
PMID: 31680923

New Perspective for Non-invasive Brain Stimulation Site Selection in Mild Cognitive Impairment: Based on Meta- and Functional Connectivity Analyses.
Liu J, Zhang B, Wilson G, Kong J, Alzheimer’s Disease Neuroimaging Initiative.
Front Aging Neurosci. 2019;11:228. doi: 10.3389/fnagi.2019.00228. Epub 2019 Aug 27.
PMID: 31551754

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.
Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group., Neurologic Outcomes Research Group (NORG).
Anesthesiology. 2018 Apr;128(4):728-744. doi: 10.1097/ALN.0000000000002103.
PMID: 29389750

Adding Recognition Discriminability Index to the Delayed Recall Is Useful to Predict Conversion from Mild Cognitive Impairment to Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.
Russo MJ, Campos J, Vazquez S, Sevlever G, Allegri RF, Alzheimer's Disease Neuroimaging Initiative.
Front Aging Neurosci. 2017;9:46. doi: 10.3389/fnagi.2017.00046. Epub 2017 Mar 10.
PMID: 28344552

Caregiver Stigma and Burden in Memory Disorders: An Evaluation of the Effects of Caregiver Type and Gender.
Kahn PV, Wishart HA, Randolph JS, Santulli RB
Curr Gerontol Geriatr Res. 2016;2016:8316045. doi: 10.1155/2016/8316045. Epub 2016 Jan 28.
PMID: 26941795

Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes.
Sloan CD, Shen L, West JD, Wishart HA, Flashman LA, Rabin LA, Santulli RB, Guerin SJ, Rhodes CH, Tsongalis GJ, McAllister TW, Ahles TA, Lee SL, Moore JH, Saykin AJ
Am J Med Genet B Neuropsychiatr Genet. 2010 Jul;153B(5):1060-9. doi: 10.1002/ajmg.b.31078.
PMID: 20468060

Judgment in Older Adults with Normal Cognition, Cognitive Complaints, MCI, and Mild AD: Relation to Regional Frontal Gray Matter.
Rabin LA, Saykin AJ, West JD, Borgos MJ, Wishart HA, Nutter-Upham KE, Flashman LA, Santulli RB
Brain Imaging Behav. 2009 Jun;3(2):212-219.
PMID: 24741381

The Memory and Aging Telephone Screen: development and preliminary validation.
Rabin LA, Saykin AJ, Wishart HA, Nutter-Upham KE, Flashman LA, Pare N, Santulli RB
Alzheimers Dement. 2007 Apr;3(2):109-21. doi: 10.1016/j.jalz.2007.02.002.
PMID: 19595923

Older adults with cognitive complaints show brain atrophy similar to that of amnestic MCI.
Saykin AJ, Wishart HA, Rabin LA, Santulli RB, Flashman LA, West JD, McHugh TL, Mamourian AC
Neurology. 2006 Sep 12;67(5):834-42.
PMID: 16966547

Increased brain activation during working memory in cognitively intact adults with the APOE epsilon4 allele.
Wishart HA, Saykin AJ, Rabin LA, Santulli RB, Flashman LA, Guerin SJ, Mamourian AC, Belloni DR, Rhodes CH, McAllister TW
Am J Psychiatry. 2006 Sep;163(9):1603-10.
PMID: 16946187

View more publications on PubMed