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John F. Modlin, MD

Title(s)
Emeritus Professor of Pediatrics
Emeritus Professor of Medicine

Additional Titles/Positions/Affiliations
Deputy Director, Polio
Bill and Melinda Gates Foundation
Seattle, WA

Department(s)
Pediatrics
Medicine

Education
Duke University, AB 1967
Duke University School of Medicine, MD 1971

Programs
Children's Hospital At Dartmouth

Curriculum Vitae
Modlin_J_CV_2009-02-13.pdf

NIH Biosketch
Modlin_J_BIO_2009-02-13.pdf

Contact Information

Bill and Melinda Gates Foundation
P.O. Box 23350
Seattle WA 98102

Phone: 206-726-7196
Email: john.modlin@gatesfoundation.org

Assistant: Megan Tucci
Asst. Email: megan.tucci@gatesfoundation.org


Selected Publications

 

Intestinal mucosal immune responses to novel oral poliovirus vaccine type 2 in healthy newborns.
Godin A, Brickley EB, Connor RI, Wieland-Alter WF, Weiner JA, Ackerman ME, Modlin JF, Sajjad OM, Arita M, Gast C, Mainou BA, Zaman K, Hoque M, Rana S, Bandyopadhyay AS, Wright PF
Clin Infect Dis. 2025 Sep 5; pii: ciaf484. doi: 10.1093/cid/ciaf484. Epub 2025 Sep 5.
PMID: 40907970

Intestinal mucosal immune responses induced by novel oral poliovirus vaccine type 2 and Sabin monovalent oral poliovirus vaccine type 2: an analysis of data from four clinical trials.
Godin A, Brickley EB, Connor RI, Wieland-Alter WF, Ackerman ME, Weiner JA, Modlin J, Arita M, Bandyopadhyay AS, Gast C, Saez-Llorens X, Ruttimann RW, Van Damme P, De Coster I, Wright PF
Lancet Microbe. 2025 Jun;6(6):101028. doi: 10.1016/j.lanmic.2024.101028. Epub 2025 Apr 30.
PMID: 40318674

Binding and neutralising antibodies to respiratory syncytial virus and influenza A virus in serum and bronchoalveolar lavage fluid of healthy adults in the United States: A cross-sectional study.
Raja AI, Connor RI, Ashare A, Weiner JA, Wieland-Alter WF, Godin A, Modlin JF, Ackerman ME, Brickley EB, Wright PF
Vaccine. 2025 Apr 19;53:126936. doi: 10.1016/j.vaccine.2025.126936. Epub 2025 Mar 3.
PMID: 40037127

Nasal and Pharyngeal Mucosal Immunity to Poliovirus in Children Following Routine Immunization With Inactivated Polio Vaccine in the United States.
Godin A, Connor RI, Degefu HN, Rosato PC, Wieland-Alter WF, Axelrod KS, Kovacikova G, Weiner JA, Ackerman ME, Chen EY, Arita M, Bandyopadhyay AS, Raja AI, Modlin JF, Brickley EB, Wright PF
J Infect Dis. 2024 Nov 15;230(5):e1023-e1030. doi: 10.1093/infdis/jiae264.
PMID: 38809190

Immunization Against Poliomyelitis and the Challenges to Worldwide Poliomyelitis Eradication.
Modlin JF, Bandyopadhyay AS, Sutter R
J Infect Dis. 2021 Sep 30;224(12 Suppl 2):S398-S404. doi: 10.1093/infdis/jiaa622.
PMID: 34590135

Mucosal immunity to poliovirus.
Connor RI, Brickley EB, Wieland-Alter WF, Ackerman ME, Weiner JA, Modlin JF, Bandyopadhyay AS, Wright PF
Mucosal Immunol. 2022 Jan;15(1):1-9. doi: 10.1038/s41385-021-00428-0. Epub 2021 Jul 8.
PMID: 34239028

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials.
De Coster I, Leroux-Roels I, Bandyopadhyay AS, Gast C, Withanage K, Steenackers K, De Smedt P, Aerssens A, Leroux-Roels G, Oberste MS, Konopka-Anstadt JL, Weldon WC, Fix A, Konz J, Wahid R, Modlin J, Clemens R, Costa Clemens SA, Bachtiar NS, Van Damme P
Lancet. 2021 Jan 2;397(10268):39-50. doi: 10.1016/S0140-6736(20)32541-1. Epub 2020 Dec 9.
PMID: 33308429

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants: two clinical trials.
Saez-Llorens X, Bandyopadhyay AS, Gast C, Leon T, DeAntonio R, Jimeno J, Caballero MI, Aguirre G, Oberste MS, Weldon WC, Konopka-Anstadt JL, Modlin J, Bachtiar NS, Fix A, Konz J, Clemens R, Costa Clemens SA, Ruttimann R
Lancet. 2021 Jan 2;397(10268):27-38. doi: 10.1016/S0140-6736(20)32540-X. Epub 2020 Dec 9.
PMID: 33308427

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden.
Brickley EB, Connor RI, Wieland-Alter WF, Collett MS, Hartford M, Van Der Avoort H, Boesch AW, Weiner JA, Ackerman ME, McKinlay MA, Arita M, Bandyopadhyay AS, Modlin JF, Wright PF
BMJ Glob Health. 2019;4(4):e001613. doi: 10.1136/bmjgh-2019-001613. Epub 2019 Aug 28.
PMID: 31543993

Progress in the development of poliovirus antiviral agents and their essential role in reducing risks that threaten eradication.
McKinlay MA, Collett MS, Hincks JR, Oberste MS, Pallansch MA, Okayasu H, Sutter RW, Modlin JF, Dowdle WR
J Infect Dis. 2014 Nov 1;210 Suppl 1:S447-53. doi: 10.1093/infdis/jiu043.
PMID: 25316866

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