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John F. Modlin, MD

Emeritus Professor of Pediatrics
Emeritus Professor of Medicine

Additional Titles/Positions/Affiliations:
Deputy Director, Polio
Bill and Melinda Gates Foundation
Seattle, WA


Duke University, AB 1967
Duke University School of Medicine, MD 1971

Children's Hospital At Dartmouth

Curriculum Vitae:

NIH Biosketch:

Contact Information:

Bill and Melinda Gates Foundation
P.O. Box 23350
Seattle WA 98102

Phone: 206-726-7196

Assistant: Megan Tucci
Asst. Email:

Selected Publications:


Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials.
De Coster I, Leroux-Roels I, Bandyopadhyay AS, Gast C, Withanage K, Steenackers K, De Smedt P, Aerssens A, Leroux-Roels G, Oberste MS, Konopka-Anstadt JL, Weldon WC, Fix A, Konz J, Wahid R, Modlin J, Clemens R, Costa Clemens SA, Bachtiar NS, Van Damme P
Lancet. 2021 Jan 2;397(10268):39-50. doi: 10.1016/S0140-6736(20)32541-1. Epub 2020 Dec 9.
PMID: 33308429

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants: two clinical trials.
Saez-Llorens X, Bandyopadhyay AS, Gast C, Leon T, DeAntonio R, Jimeno J, Caballero MI, Aguirre G, Oberste MS, Weldon WC, Konopka-Anstadt JL, Modlin J, Bachtiar NS, Fix A, Konz J, Clemens R, Costa Clemens SA, Ruttimann R
Lancet. 2021 Jan 2;397(10268):27-38. doi: 10.1016/S0140-6736(20)32540-X. Epub 2020 Dec 9.
PMID: 33308427

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden.
Brickley EB, Connor RI, Wieland-Alter WF, Collett MS, Hartford M, Van Der Avoort H, Boesch AW, Weiner JA, Ackerman ME, McKinlay MA, Arita M, Bandyopadhyay AS, Modlin JF, Wright PF
BMJ Glob Health. 2019;4(4):e001613. doi: 10.1136/bmjgh-2019-001613. Epub 2019 Aug 28.
PMID: 31543993

Progress in the development of poliovirus antiviral agents and their essential role in reducing risks that threaten eradication.
McKinlay MA, Collett MS, Hincks JR, Oberste MS, Pallansch MA, Okayasu H, Sutter RW, Modlin JF, Dowdle WR
J Infect Dis. 2014 Nov 1;210 Suppl 1:S447-53. doi: 10.1093/infdis/jiu043.
PMID: 25316866

Atypical hand, foot, and mouth disease: a vesiculobullous eruption caused by Coxsackie virus A6.
Feder HM Jr, Bennett N, Modlin JF
Lancet Infect Dis. 2014 Jan;14(1):83-86. doi: 10.1016/S1473-3099(13)70264-0. Epub 2013 Nov 25.
PMID: 24287184

Inactivated polio vaccine and global polio eradication.
Modlin JF
Lancet Infect Dis. 2012 Feb;12(2):93-4. doi: 10.1016/S1473-3099(11)70312-7. Epub 2011 Nov 7.
PMID: 22071250

A fatal central nervous system enterovirus 68 infection.
Kreuter JD, Barnes A, McCarthy JE, Schwartzman JD, Oberste MS, Rhodes CH, Modlin JF, Wright PF
Arch Pathol Lab Med. 2011 Jun;135(6):793-6. doi: 10.1043/2010-0174-CR.1.
PMID: 21631275

The bumpy road to polio eradication.
Modlin JF
N Engl J Med. 2010 Jun 24;362(25):2346-9. doi: 10.1056/NEJMp1005405.
PMID: 20573922

When to consider the use of antibiotics in the treatment of 2009 H1N1 influenza-associated pneumonia.
Wright PF, Kirkland KB, Modlin JF
N Engl J Med. 2009 Dec 10;361(24):e112. doi: 10.1056/NEJMopv0910749.
PMID: 19940288

Empiric antibiotics are justified for infants with respiratory syncytial virus lower respiratory tract infection presenting with respiratory failure: a prospective study and evidence review.
Levin D, Tribuzio M, Green-Wrzesinki T, Ames B, Radwan S, Jarvis JD, Vaccaro T, Modlin JF
Pediatr Crit Care Med. 2010 May;11(3):390-5. doi: 10.1097/PCC.0b013e3181b809c5.
PMID: 19838143

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