Two nationally and internationally recognized interdepartmental research and education programs, the Geisel School of Medicine's Immunology Program and Microbiology & Molecular Pathogenesis Program (M2P2), are centered in the Microbiology and Immunology Department. The Immunology Program involves a variety of investigative efforts, including those related to T and B lymphocyte immunobiology; myeloid cell immunobiology; the immunology of the human female reproductive tract; cancer immunobiology; immunity to bacteria and viruses, including HIV; mucosal immune responses; signaling in cells of the immune system; the development and use of monoclonal antibodies and other engineered biomolecules in the diagnosis and treatment of tumors and infectious diseases; autoimmune diseases, and the design of vaccines. Departmental faculty have a strong record of applying basic research findings to the treatment of human disease. The M2P2 at Dartmouth is an interactive, multidisciplinary program that involves researchers from the Departments of Microbiology and Immunology, Biology, Biochemistry, Physiology, and Medicine. Areas of research include molecular genetics of bacterial, fungal, parasitic, and viral pathogenesis; cellular and immunobiology of parasites; host-pathogen interactions; microbe-microbe interactions; evolution and regulation of bacterial virulence; immune mechanisms in resistance to infectious diseases; therapeutics; and vaccine design. All Microbiology and Immunology faculty members participate in either the Molecular Pathogenesis or the Immunology Program and many participate in both.