Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.
Moreno de Lara L, Werner A, Borchers A, Carrillo-Salinas FJ, Marmol W, Parthasarathy S, Iyer V, Vogell A, Illanes D, Abadia-Molina AC, Ochsenbauer C, Wira CR, Rodriguez-Garcia M
Front Immunol. 2023;14:1256182. doi: 10.3389/fimmu.2023.1256182. Epub 2023 Nov 15.
PMID: 38035114
A rise in the frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021.
Shanks RMQ, Atta S, Stella NA, Sundar-Raj CV, Romanowski JE, Grewal AS, Shanks HQ, Mumper SM, Dhaliwal DK, Mammen A, Callaghan JD, Calvario RC, Romanowski EG, Kowalski RP, Zegans ME, Jhanji V
Front Cell Infect Microbiol. 2023;13:1286842. doi: 10.3389/fcimb.2023.1286842. Epub 2023 Oct 31.
PMID: 38029269
ATP-dependent transporters: emerging players at the crossroads of immunity and metabolism.
Balasubramanian A, Sundrud MS
Front Immunol. 2023;14:1286696. doi: 10.3389/fimmu.2023.1286696. Epub 2023 Oct 31.
PMID: 38022644
Rocket-miR, a translational launchpad for miRNA-based antimicrobial drug development.
Neff SL, Hampton TH, Koeppen K, Sarkar S, Latario CJ, Ross BD, Stanton BA
mSystems. 2023 Nov 17;:e0065323. doi: 10.1128/msystems.00653-23. Epub 2023 Nov 17.
PMID: 37975659
Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.
Carreno-Florez GP, Kocak BR, Hendricks MR, Melvin JA, Mar KB, Kosanovich J, Cumberland RL, Delgoffe GM, Shiva S, Empey KM, Schoggins JW, Bomberger JM
PLoS Pathog. 2023 Nov;19(11):e1011719. doi: 10.1371/journal.ppat.1011719. Epub 2023 Nov 8.
PMID: 37939149
Biofilms 2022: back and better than ever.
O'Toole GA
J Bacteriol. 2023 Nov 6;205(11):e0022523. doi: 10.1128/jb.00225-23. Epub 2023 Nov 6.
PMID: 37930065
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
Biswas S, Mandal G, Anadon CM, Chaurio RA, Lopez-Bailon LU, Nagy MZ, Mine JA, Hanggi K, Sprenger KB, Innamarato P, Harro CM, Powers JJ, Johnson J, Fang B, Eysha M, Nan X, Li R, Perez BA, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR
Immunity. 2023 Nov 14;56(11):2570-2583.e6. doi: 10.1016/j.immuni.2023.09.013. Epub 2023 Oct 30.
PMID: 37909039
Community composition and the environment modulate the population dynamics of type VI secretion in human gut bacteria.
Robitaille S, Simmons EL, Verster AJ, McClure EA, Royce DB, Trus E, Swartz K, Schultz D, Nadell CD, Ross BD
Nat Ecol Evol. 2023 Oct 26; doi: 10.1038/s41559-023-02230-6. Epub 2023 Oct 26.
PMID: 37884689
Dense granule protein 3 of Toxoplasma gondii plays a crucial role in the capability of the tissue cysts of the parasite to persist in the presence of anti-cyst CD8(+) T cells during the chronic stage of infection.
Mani R, Abdelaziz MH, Ochiai E, Sa Q, Fox BA, Bzik DJ, Suzuki Y
Front Immunol. 2023;14:1272221. doi: 10.3389/fimmu.2023.1272221. Epub 2023 Oct 5.
PMID: 37868957
Immunogenicity Threshold in Allogeneic Cells Impacts CTL Response to Nondominant Congenic Antigens.
Rawat K, Mara AB, King WT, Nnam CF, Jakubzick CV
J Immunol. 2023 Dec 1;211(11):1623-1629. doi: 10.4049/jimmunol.2300548.
PMID: 37850969
The cystic fibrosis treatment Trikafta affects the growth, viability, and cell wall of Aspergillus fumigatus biofilms.
Jones JT, Morelli KA, Vesely EM, Puerner CTS, Pavuluri CK, Ross BS, van Rhijn N, Bromley MJ, Cramer RA
mBio. 2023 Oct 13;14(5):e0151623. doi: 10.1128/mbio.01516-23. Epub 2023 Oct 13.
PMID: 37830825
Aspergillus fumigatus cytochrome c impacts conidial survival during sterilizing immunity.
James MR, Aufiero MA, Vesely EM, Dhingra S, Liu KW, Hohl TM, Cramer RA
mSphere. 2023 Oct 12;:e0030523. doi: 10.1128/msphere.00305-23. Epub 2023 Oct 12.
PMID: 37823656
Host Genetic Variation Has a Profound Impact on Immune Responses Mediating Control of Viral Load in Chronic Gammaherpesvirus Infection.
Holt EA, Waytashek CM, Sessions KJ, Asarian L, Lahue KG, Usherwood EJ, Teuscher C, Krementsov DN
J Immunol. 2023 Nov 15;211(10):1526-1539. doi: 10.4049/jimmunol.2300294.
PMID: 37819784
Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights.
Noelle RJ, Lines JL, Lewis LD, Martell RE, Guillaudeux T, Lee SW, Mahoney KM, Vesely MD, Boyd-Kirkup J, Nambiar DK, Scott AM
Front Oncol. 2023;13:1225081. doi: 10.3389/fonc.2023.1225081. Epub 2023 Sep 15.
PMID: 37795437
Phosphoprotein phosphatase activity positively regulates oligomeric pyrin to trigger inflammasome assembly in phagocytes.
Malik HS, Magnotti F, Loeven NA, Delgado JM, Kettenbach AN, Henry T, Bliska JB
mBio. 2023 Oct 3;14(5):e0206623. doi: 10.1128/mbio.02066-23. Epub 2023 Oct 3.
PMID: 37787552
Transcriptional profiling and genetic analysis of a cystic fibrosis airway-relevant model shows asymmetric responses to growth in a polymicrobial community.
Kesthely CA, Rogers RR, El Hafi B, Jean-Pierre F, O'Toole GA
Microbiol Spectr. 2023 Sep 29;11(5):e0220123. doi: 10.1128/spectrum.02201-23. Epub 2023 Sep 29.
PMID: 37772884
Transcriptomics of Canine Inflammatory Mammary Cancer Treated with Empty Cowpea Mosaic Virus Implicates Neutrophils in Anti-Tumor Immunity.
Barreno L, Sevane N, Valdivia G, Alonso-Miguel D, Suarez-Redondo M, Alonso-Diez A, Fiering S, Beiss V, Steinmetz NF, Perez-Alenza MD, Peña L
Int J Mol Sci. 2023 Sep 13;24(18) doi: 10.3390/ijms241814034. Epub 2023 Sep 13.
PMID: 37762335
Neoadjuvant Intratumoral Immunotherapy with Cowpea Mosaic Virus Induces Local and Systemic Antitumor Efficacy in Canine Mammary Cancer Patients.
Valdivia G, Alonso-Miguel D, Perez-Alenza MD, Zimmermann ABE, Schaafsma E, Kolling FW 4th, Barreno L, Alonso-Diez A, Beiss V, Affonso de Oliveira JF, Suarez-Redondo M, Fiering S, Steinmetz NF, Vom Berg J, Peña L, Arias-Pulido H
Cells. 2023 Sep 8;12(18) doi: 10.3390/cells12182241. Epub 2023 Sep 8.
PMID: 37759464
Bacterial Outer Membrane Vesicles and Immune Modulation of the Host.
Charpentier LA, Dolben EF, Hendricks MR, Hogan DA, Bomberger JM, Stanton BA
Membranes (Basel). 2023 Aug 24;13(9) doi: 10.3390/membranes13090752. Epub 2023 Aug 24.
PMID: 37755174
Double-anonymous peer review comes to JB.
O'Toole GA
J Bacteriol. 2023 Oct 26;205(10):e0008022. doi: 10.1128/jb.00080-22. Epub 2023 Sep 25.
PMID: 37747191