Recent Publications

Long Covid: Untangling the Complex Syndrome and the Search for Therapeutics

Azizul Haque, Anudeep B. Pant

Community composition and the environment modulate the population dynamics of type VI secretion in human gut bacteria.
Robitaille S, Simmons EL, Verster AJ, McClure EA, Royce DB, Trus E, Swartz K, Schultz D, Nadell CD, Ross BD
bioRxiv. 2023 Feb 21; pii: 2023.02.20.529031. doi: 10.1101/2023.02.20.529031. Epub 2023 Feb 21.
PMID: 36865186

Combining in situ vaccination and immunogenic apoptosis to treat cancer.
Kalami A, Shahgolzari M, Khosroushahi AY, Fiering S
Immunotherapy. 2023 Apr;15(5):367-381. doi: 10.2217/imt-2022-0137. Epub 2023 Feb 27.
PMID: 36852419

Porous marine snow differentially benefits chemotactic, motile, and nonmotile bacteria.
Borer B, Zhang IH, Baker AE, O'Toole GA, Babbin AR
PNAS Nexus. 2023 Feb;2(2):pgac311. doi: 10.1093/pnasnexus/pgac311. Epub 2022 Dec 26.
PMID: 36845354

Cell type-specific Interaction Analysis using Doublets in scRNA-seq (CIcADA).
Schiebout C, Lust HE, Huang YH, Frost HR
bioRxiv. 2023 Feb 15; pii: 2023.02.13.528326. doi: 10.1101/2023.02.13.528326. Epub 2023 Feb 15.
PMID: 36824707

mSphere of Influence: Learning Biology from the Radio.
Schultz D
mSphere. 2023 Feb 21;8(1):e0002623. doi: 10.1128/msphere.00026-23. Epub 2023 Feb 2.
PMID: 36728432

The History of Microbial Model Systems.
O'Toole GA
J Bacteriol. 2023 Feb 22;205(2):e0003023. doi: 10.1128/jb.00030-23. Epub 2023 Feb 1.
PMID: 36722958

Virology under the Microscope-a Call for Rational Discourse.
Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, Brooke C, Cameron C, Campos S, Caposio P, Chan G, Cliffe A, Coffin J, Collins K, Damania B, Daugherty M, Debbink K, DeCaprio J, Dermody T, Dikeakos J, DiMaio D, Dinglasan R, Duprex WP, Dutch R, Elde N, Emerman M, Enquist L, Fane B, Fernandez-Sesma A, Flenniken M, Frappier L, Frieman M, Frueh K, Gack M, Gaglia M, Gallagher T, Galloway D, Garcia-Sastre A, Geballe A, Glaunsinger B, Goff S, Greninger A, Hancock M, Harris E, Heaton N, Heise M, Heldwein E, Hogue B, Horner S, Hutchinson E, Hyser J, Jackson W, Kalejta R, Kamil J, Karst S, Kirchhoff F, Knipe D, Kowalik T, Lagunoff M, Laimins L, Langlois R, Lauring A, Lee B, Leib D, Liu SL, Longnecker R, Lopez C, Luftig M, Lund J, Manicassamy B, McFadden G, McIntosh M, Mehle A, Miller WA, Mohr I, Moody C, Moorman N, Moscona A, Mounce B, Munger J, Munger K, Murphy E, Naghavi M, Nelson J, Neufeldt C, Nikolich J, O'Connor C, Ono A, Orenstein W, Ornelles D, Ou JH, Parker J, Parrish C, Pekosz A, Pellett P, Pfeiffer J, Plemper R, Polyak S, Purdy J, Pyeon D, Quinones-Mateu M, Renne R, Rice C, Schoggins J, Roller R, Russell C, Sandri-Goldin R, Sapp M, Schang L, Schmid S, Schultz-Cherry S, Semler B, Shenk T, Silvestri G, Simon V, Smith G, Smith J, Spindler K, Stanifer M, Subbarao K, Sundquist W, Suthar M, Sutton T, Tai A, Tarakanova V, tenOever B, Tibbetts S, Tompkins S, Toth Z, van Doorslaer K, Vignuzzi M, Wallace N, Walsh D, Weekes M, Weinberg J, Weitzman M, Weller S, Whelan S, White E, Williams B, Wobus C, Wong S, Yurochko A
mBio. 2023 Feb 28;14(1):e0018823. doi: 10.1128/mbio.00188-23. Epub 2023 Jan 26.
PMID: 36700642

Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system.
Jean-Pierre F, Hampton TH, Schultz D, Hogan DA, Groleau MC, Deziel E, O'Toole GA
Elife. 2023 Jan 20;12 doi: 10.7554/eLife.81604. Epub 2023 Jan 20.
PMID: 36661299

Tumor-Derived Extracellular Vesicles in Cancer Immunoediting and Their Potential as Oncoimmunotherapeutics.
Najaflou M, Shahgolzari M, Khosroushahi AY, Fiering S
Cancers (Basel). 2022 Dec 23;15(1) doi: 10.3390/cancers15010082. Epub 2022 Dec 23.
PMID: 36612080

Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins.
Oh C, Li L, Verma A, Reuven AD, Miao EA, Bliska JB, Aachoui Y
Cell Rep. 2022 Nov 22;41(8):111688. doi: 10.1016/j.celrep.2022.111688.
PMID: 36417874

Intraspecies Signaling between Common Variants of Pseudomonas aeruginosa Increases Production of Quorum-Sensing-Controlled Virulence Factors
Dallas L. Mould, Nico J. Botelho, Deborah A. Hogan
DOI: 10.1128/mBio.01865-20

Analysis of CRISPR/Cas9 Guide RNA Efficiency and Specificity Against Genetically Diverse HIV-1 Isolates
Katherine J. Sessions, Yun Yue Chen, Christine A. Hodge, Taylor R. Hudson, Susan K. Eszterhas, Matthew S. Hayden, and Alexandra Howell
DOI: 10.1089/aid.2020.0055

Conditional antagonism in co-cultures of Pseudomonas aeruginosa and Candida albicans: An Intersection of etanol and phosphate signaling distilled from dual-seq transcriptomics
Georgia Doing, Katja Koeppen, Patricia Occipinti, Colleen E. Harty, Deborah A. Hogan
DOI: 10.1371/journal.pgen.1008783

Mitigating Covid-19 in the face of emerging virus variants, breakthrough infections and vaccine hesitancy
Azizul Haque, Anudeep B. Pant

Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma
Aleksey K. Molodtsov, Nikhil Khatwani, Jennifer L. Vella, Yina H. Huang, Chao Cheng, Mary Jo Turk