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About the Program

Many Molecular and Systems Biology faculty participate in The Program in Experimental and Molecular Medicine (PEMM) graduate program offered at Dartmouth Medical School and Dartmouth College. PEMM is a degree-granting program that encompasses three broad over-lapping disciplines ("themes"):

  • Biomedical Physiology & Immunotherapy
  • Cancer Biology, Pharmacology and Molecular Therapeutics
  • Neuroscience

PEMM seeks to train the next generation of scientists and physician-scientists to engage in genomic, proteomic, cellular, and organ-based systems research for the purpose of translating this knowledge into disease treatment and prevention.

The curriculum for PEMM offers broad training in fundamental concepts of human biology at the molecular cell and organism levels, while also offering specific instruction in the diverse areas encompassed by the umbrella program. A core course is taken by all PEMM students for the first two terms, which covers the fundamentals of cell biology, molecular biology, physiology, pharmacology, toxicology, immunology, and human genetics. Instruction in this course focuses on human pathophysiology, using specific examples to illustrate how molecular mechanisms translate into distinct diseases. All students take an ethics course in their first year as well as participate in a journal club each term. Electives are selected from a comprehensive group of advanced graduate courses. Three one-term rotations in the laboratory of individual faculty members train students in research techniques and allow them to select a thesis advisor from among their rotation sponsors.

Research carried out by faculty and trainees in this program will use the most advanced experimental approaches to understand the pathophysiology of disease and to develop new diagnostics and therapeutics. Students will have the opportunity to be mentored by faculty within both the basic and clinical sciences. The research will employ a broad range of biochemical, biological, and molecular techniques, and will interface with related disciplines such as biostatistics, bioinformatics, structural biology, and chemistry. All students will be given thorough instruction in the fundamentals of cell biology, molecular biology, physiology and pathophysiology, pharmacology, and human genetics. In addition, there will be special courses on designing, implementing and analyzing clinical trials. Thus, this program is expected to provide students with a broad-based understanding of key biomedical problems and to develop their ability to carry out creative biomedical research.

To apply using our Online Application Form, fill out the information requested and submit the form.