The Department of Molecular and Systems Biology (MSB) at The Geisel School of Medicine at Dartmouth was formed in 2016 to unite faculty with diverse scientific interests and technical expertise who are answering complex questions in biology and medicine through systems level, state-of-the-art experimental and computational approaches. With strengths in cancer biology, proteomics, neuroscience, developmental biology, genomics and genetics, department labs span the breadth of cutting-edge research – from mechanisms underlying gene regulation and signaling pathways in developing organisms and circadian systems, to optogenetic control and live imaging of neural circuits, to insights into disease processes and innovative therapies to combat them.
Department of Molecular and Systems Biology
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Open Faculty Position
Tenure-Track Faculty Position In Molecular and Systems Biology
The Department of Molecular and Systems Biology at Geisel School of Medicine at Dartmouth invites applications for a tenure-track Assistant Professor. We seek applicants who will direct an independent and innovative research program to understand complex problems in molecular, cellular, or developmental biology, regeneration, neuroscience, or mechanisms of disease using approaches in genetics, genomics, epigenetics, metabolomics, bioinformatics, or computational systems biology.
Grant Proposal Questionnaire
Upcoming Seminars
- Department of Medicine Grand Rounds
December 6, 2024 - 9:00 amPlease join us for an IN-PERSON Medicine Grand Rounds,
December 6, 2024
8:00 a.m. – 9:00 a.m.
There will be a light breakfast served from 7:30-8:00 a.m.
“Age Friendly Learning Health Systems
in Hospital Medicine”
James Harrison MPH PhD
Associate Professor of Medicine
Division of Hospital Medicine
University of California San Francisco
Research Director, UCSF Age Friendly Health System
We encourage you to join us in Auditorium E
or
you may join via WebEx:
Medicine Grand Rounds Link
Co-Sponsored by the Section of Hospital Medicine and the Department of Medicine
Geisel School of Medicine at Dartmouth
Session Learning Objectives:
1. To describe the rationale for Age Friendly Health Systems
2. To understand the concept of an Age Friendly Learning Health System
3. To apply Age Friendly Learning Health System principles to research and quality improvement in Hospital Medicine
About our presenter:
Dr. James Harrison is an Associate Professor of Medicine in the Division of Hospital Medicine at the University of California San Francisco. James is a researcher and implementation scientist who uses patient engagement to improve the hospital care transitions of older adults. He seeks to develop and implement care transition interventions that bring the patient voice to the forefront and are then sustained in real-world clinical settings. James also has a leadership role within UCSF Health’s Age Friendly Health System where he is Research Director. In this role he seeks to build capacity and research infrastructure that catalyzes the dissemination of research evidence that improves the engagement, outcomes, experiences, and dignity of older adults within health systems. In addition to his aging research portfolio, James' growing area of research interest and expertise relates to engagement science. He has completed several PCORI funded studies seeking to explore and describe the methods and best practices of
engaging patients and community members as partners in research. James joined the UCSF Division of Hospital Medicine as a Research Specialist in 2012 before moving to a faculty position in 2016. Prior to joining UCSF, James was based at the Surgical Outcomes Research Centre at the University of Sydney and Royal Prince Alfred Hospital. It was in Sydney, Australia that James completed his MPH and PhD.
Please join the Department of Medicine in welcoming Dr. Harrison for Medicine Grand Rounds.
Accreditation:
In support of improving patient care, Dartmouth Health is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Dartmouth Health designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
If you would like to view Grand Rounds at a different time, you can find an archived edition at this link:
http://video.dartmouth-hitchcock.org
Please note: in order to receive credit for attending this conference you must complete the mobile sign-in within 48 hours of the presentation. Use the text-in number 833-884-3375 (please note the new phone number) from your phone. Activity codes will not be provided until the time of the presentation.
Please email Laura Mitchell (laura.m.mitchell@hitchcock.org), Biz Gobin (elizabeth.a.gobin@hitchcock.org) or Ryan Flynn (Ryan.A.Flynn@hitchcock.org) with questions - BCB Special Seminar - Joachim Herz, MD
December 6, 2024 - 11:00 amBiochemistry & Cell Biology Seminar
Friday, December 6, 2024
10:00am – 11:00am
Kellogg 200
“ApoE and the Aging Brain”
Joachim Herz, MD
Director
Center for Translational Neurodegeneration Research
Host: TY Chang, PhD
If you have any questions, please email Jenni.Hinsley@dartmouth.edu.
MSB Department News
Dr. Esteban Orellana (MSB), in collaboration with Dr. Soni Lacefield (BCB), launched The International Summer Undergraduate Research Experience (ISURE), which brings undergraduate students from partner universities in Africa and Ecuador to Dartmouth to perform research in biomedical labs for 8 weeks during the summer. Through ISURE, Dartmouth serves as a leader in the role of broadening the global network of STEM researchers. The program aims to promote exchange and collaboration between Dartmouth College and disadvantaged countries in Africa (Kenya) and Latin America (Ecuador) to promote advances in research and STEM student retention. STEM researchers in developing countries often lack opportunities for state-of-the-art research, limiting students' exposure to career options. These issues often represent a roadblock that slows down the scientific advancement of a developing country, which could be addressed by collaboration with investigators/laboratories in the United States.
The 2024 Tenney Fellowship has been awarded to Dr. Shannon Paquette, from the Kasper lab. The fellowship was created in 2002 to honor the memory of Dr. Stephen Marsh Tenney, MD. Dr. Paquette is exploring how a specific transcriptional regulator, IRF8, establishes functionally distinct macrophage subsets in the context of tissue development and hematopoietic balance. Genetic mutations of IRF8 have been identified in hematologic cancers and several autoimmune disorders, but it is unknown how perturbed macrophage heterogeneity drives these pathologies. By capitalizing on the advantages of zebrafish as a developmental model system, Dr. Paquette will address the knowledge gap between the known consequences of IRF8 loss and its unknown functions in dictating hematopoietic diversity.
Department Newsletter
Looking for another MSB graduate student to join our seminar committee and help select speakers for MSB Monday seminars. Also looking for a graduate student and a post-doc to serve on MSB’s Enriching our Environment committee. Great opportunities for leadership experience! E-mail molecular.and.systems.biology@dartmouth.edu