The Geisel School of Medicine at Dartmouth has nucleated a Department of Molecular and Systems Biology that is poised to exploit and contribute to the explosive growth in information and its application to solving problems in biological systems. The department is piloted by salient and similarly minded research faculty with expertise in genetics, physiology, cancer biology, neuroscience, and pharmacology. This is the new Department of Molecular and Systems Biology.
Department of Molecular and Systems Biology
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Faculty Research Awards and Grants
Todd Miller, PhD: Lighting a New Path in Breast Cancer Research
His mission is figuring out how to kill breast cancer cells by manipulating the complicated signals that turn their growth on and off. This complexity is what initially attracted Miller to biology. "Other sciences like physics or chemistry were bounded by hard and fast rules, but biological systems are so infinitely complex it feels like there is more room for exploration."
Associate Professor Yolanda Sanchez recognized by Graduate Studies Faculty Mentoring Award
The Faculty Mentoring Award is given annually to a member of the Dartmouth faculty who exemplifies a deep commitment to fostering the professional and personal development of graduate students. This year's recipients are Professor David Glueck, from the department of Chemistry and Yolanda Sanchez, Associate Professor of Molecular and Systems Biology and Associate Director for Basic Sciences, Norris Cotton Cancer Center.
Geisel Researcher Appointed to Cohn Professorship
Giovanni Bosco, PhD, a professor of Molecular and Systems Biology, has been appointed to the Oscar M. Cohn 1934 Professorship.
Understanding Scleroderma's 'Social Network' May Lead to New Treatments
Michael Whitfield, PhD, a translational genetics researcher at Dartmouth's Geisel School of Medicine, has earned a second highly competitive award from the Dr. Ralph and Marian Falk Medical Research Trust for his pioneering work on the rare autoimmune disease systemic scleroderma.
Department News
Today, the Gerber Laboratory is a world leader in applying spectrometry-based proteomics approaches to better understand the function of proteins in cells and what goes wrong during cell division in cancer. “In particular, we’re interested in how proteins talk to one another through a process called cell signaling,” he explains.
Researchers Find Source of Breast Tumor Heterogeneity and Pathway that Limits Emergence
A key hurdle in treating breast cancers is intratumoral heterogeneity, or the presence of multiple different cell populations within the same tumor that have distinct characteristics such as gene expression, metabolism and ability to divide, spread and grow.
Miller Lab - Researchers discover a key to the survival of dormant breast cancer cells.
The results, entitled "AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells," are newly published online in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Gio Bosco and members of his lab are recognized for the 2019 PLOS Genetics Research Prize: Fruit fly school - language and dialect for communicating a threat
Practicing and publishing science has many rewards, and one of the best is the opportunity to pause and recognize truly exceptional work done by members of your research community. It is in this spirit that we launched the annual PLOS Genetics Research Prize several years ago. The prize recognizes a paper published in the last year that is scientifically outstanding and has broad reach across the genetics community.
Gerber Named the Inaugural Kenneth E. and Carol L. Weg Distinguished Professor
Scott A. Gerber, PhD, professor of molecular and systems biology and of biochemistry and cell biology at the Geisel School of Medicine at Dartmouth, and program director of the Cancer Biology and Therapeutics Research Program at Dartmouth’s Norris Cotton Cancer Center (NCCC), has been named the Kenneth E. and Carol L. Weg Distinguished Professor. An expert in mass spectrometry and proteomics, Gerber is the first to hold this newly established professorship given by Kenneth Weg D ’60 and his wife, Carol Weg.
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