Inflammatory Dermatology and Contact Dermatitis

Description: Extensive research on allergen identification, prevalence studies, and clinical outcomes in contact dermatitis through the North American Contact Dermatitis Group database. Studies on various inflammatory dermatoses including their pathogenesis, clinical presentation, and treatment approaches.

Inflammatory dermatology disease
Example of inflammatory dermatitis

Key publications

Patch Testing

  • Warshaw EM, Ruggiero JL, DeKoven JG, Pratt MD, Silverberg JI, Maibach HI, Zug KA, Atwater AR, Taylor JS, Reeder MJ, Sasseville D, Fowler JF Jr, Fransway AF, Belsito DV, DeLeo VA, Houle MC, Dunnick CA. Patch testing with ammonium persulfate: The North American Contact Dermatitis Group Experience, 2015-2018. J Am Acad Dermatol. 2022 Nov;87(5):1014-1023. doi: 10.1016/j.jaad.2021.08.005. Epub 2021 Aug 11. PMID: 34390784.
  •  Silverberg JI, Hou A, Warshaw EM, DeKoven JG, Maibach HI, Belsito DV, Zug KA, Taylor JS, Sasseville D, Dunnick CA, Houle MC, Atwater AR, Reeder MJ, DeLeo VA, Pratt MD, Fowler JF Jr, Zirwas MJ, Marks JG Jr. Age-related differences in patch testing results among children: Analysis of North American Contact Dermatitis Group Data, 2001-2018. J Am Acad Dermatol. 2022 Apr;86(4):818-826. doi: 10.1016/j.jaad.2021.07.030. Epub 2021 Jul 24. PMID: 34314743.
  •  DeLeo VA, Adler BL, Warshaw EM, Maibach HI, Belsito DV, Fowler JF Jr, Fransway AF, Marks JG Jr, Mathias CGT, Pratt MD, Rietschel RL, Storrs FJ, Zug KA, Sasseville D. Photopatch test results of the North American contact dermatitis group, 1999-2009. Photodermatol Photoimmunol Photomed. 2022 May;38(3):288-291. doi: 10.1111/phpp.12742. Epub 2021 Oct 25. Erratum in: Photodermatol Photoimmunol Photomed. 2023 Mar;39(2):181. doi: 10.1111/phpp.12859. PMID: 34651348.

Allergens

  • Silverberg JI, Hou A, Warshaw EM, Maibach HI, Belsito DV, DeKoven JG, Zug KA, Taylor JS, Sasseville D, Fransway AF, DeLeo VA, Pratt MD, Reeder MJ, Atwater AR, Fowler JF Jr, Zirwas MJ, Marks JG Jr, Dunnick CA, Houle MC. Allergens in patients with a diagnosis of seborrheic dermatitis, North American Contact Dermatitis Group data, 2001-2016. J Am Acad Dermatol. 2022 Feb;86(2):460-463. doi: 10.1016/j.jaad.2021.09.039. Epub 2021 Sep 25. PMID: 34582838.
  •  Atwater AR, Ward JM, Liu B, Green CL, Belsito DV, Sasseville D, DeKoven JG, Reeder MJ, Taylor JS, Maibach HI, Silverberg JI, Zug KA, Fowler JF Jr, Pratt MD, DeLeo VA, Warshaw EM. Fragrance- and Botanical-Related Allergy and Associated Concomitant Reactions: A Retrospective Analysis of the North American Contact Dermatitis Group Data 2007-2016. Dermatitis. 2021 Jan-Feb 01;32(1):42-52. doi: 10.1097/DER.0000000000000661. PMID: 33273222.
  •  Warshaw EM, Schlarbaum JP, Taylor JS, Silverberg JI, DeKoven JG, Atwater AR, Zug KA, Zirwas MJ, Reeder MJ, Fowler JF Jr, Marks JG Jr, DeLeo VA, Belsito DV, Maibach HI, Fransway AF, Sasseville D, Pratt MD, Mathias CGT. Allergic reactions to tattoos: Retrospective analysis of North American Contact Dermatitis Group data, 2001-2016. J Am Acad Dermatol. 2020 Feb;82(2):e61-e62. doi: 10.1016/j.jaad.2019.09.077. Epub 2019 Oct 8. PMID: 31604096.
  •  Shaker M, Murray RGP, Mann JA. The ins and outs of an 'outside-in' view of allergies: atopic dermatitis and allergy prevention. Curr Opin Pediatr. 2018 Aug;30(4):576-581. doi: 10.1097/MOP.0000000000000646. PMID: 29750772.

Eczema

  • Thyssen JP, Schuttelaar MLA, Alfonso JH, Andersen KE, Angelova-Fischer I, Arents BWM, Bauer A, Brans R, Cannavo A, Christoffers WA, Crépy MN, Elsner P, Fartasch M, Filon FL, Giménez-Arnau AM, Gonçalo M, Guzmán-Perera MG, Hamann CR, Hoetzenecker W, Johansen JD, John SM, Kunkeler ACM, Hadzavdic SL, Molin S, Nixon R, Oosterhaven JAF, Rustemeyer T, Serra-Baldrich E, Shah M, Simon D, Skudlik C, Spiewak R, Valiukevičienė S, Voorberg AN, Weisshaar E, Agner T. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis. 2022 May;86(5):357-378. doi: 10.1111/cod.14035. Epub 2022 Mar 3. PMID: 34971008.
  • Silverberg JI, Warshaw EM, Maibach HI, DeKoven JG, Taylor JS, Atwater AR, Sasseville D, Zug KA, Reeder MJ, Fowler JF Jr, Pratt MD, Fransway AF, Zirwas MJ, Belsito DV, Marks JG Jr, DeLeo VA. Hand eczema in children referred for patch testing: North American Contact Dermatitis Group Data, 2000-2016. Br J Dermatol. 2021 Jul;185(1):185-194. doi: 10.1111/bjd.19818. Epub 2021 Mar 31. PMID: 33454963.
  • Chan CX, Zug KA. Diagnosis and Management of Dermatitis, Including Atopic, Contact, and Hand Eczemas. Med Clin North Am. 2021 Jul;105(4):611-626. doi: 10.1016/j.mcna.2021.04.003. PMID: 34059241.

Hidradenitis Suppurativa

  • Saad A, Cahn B, Haber R. Unveiling the Green Connection: Cannabis as a Potential Trigger for Hidradenitis Suppurativa. Arch Dermatol Res. 2024 May 2;316(5):141. doi: 10.1007/s00403-024-02878-5. PMID: 38695996.
  • Fragoso NM, Masson R, Shih T, Mayo T, Okoye G, Shi VY, Hsiao JL. No-shows to hidradenitis suppurativa clinic visits: Patient perspectives. Skin Health Dis. 2023 Dec 10;4(2):e322. doi: 10.1002/ski2.322. PMID: 38577047; PMCID: PMC10988716.
  • Fragoso NM, Masson R, Gillenwater TJ, Shi VY, Hsiao JL. Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa Part I: Topical and Systemic Medical Therapies. Dermatol Ther (Heidelb). 2023 Aug;13(8):1661-1697. doi: 10.1007/s13555-023-00956-6. Epub 2023 Jul 4. PMID: 37402031; PMCID: PMC10366071.
  • Fragoso NM, Masson R, Gillenwater TJ, Shi VY, Hsiao JL. Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa-Part II: Procedural and Wound Care Therapies. Dermatol Ther (Heidelb). 2023 Aug;13(8):1699-1720. doi: 10.1007/s13555-023-00957-5. Epub 2023 Jul 4. PMID: 37402030; PMCID: PMC10366058.

Faculty

Natalie Fragoso headshot

Natalie Fragoso, MD

  • Assistant Professor of Dermatology
  • Residency Program Director

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Kathryn Zug headshot

Kathryn Zug, MD

  • Emeritus Professor of Dermatology

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