An atlas of RNA-dependent proteins in cell division reveals the riboregulation of mitotic protein-protein interactions.
Rajagopal V, Seiler J, Nasa I, Cantarella S, Theiss J, Herget F, Kaifer B, Klostermann M, Will R, Schneider M, Helm D, Konig J, Zarnack K, Diederichs S, Kettenbach AN, Caudron-Herger M
Nat Commun. 2025 Mar 8;16(1):2325. doi: 10.1038/s41467-025-57671-3. Epub 2025 Mar 8.
PMID: 40057470
PP2A-B56 regulates Mid1 protein levels for proper cytokinesis in fission yeast.
Chrupcala ML, Moseley JB
Mol Biol Cell. 2025 Apr 1;36(4):ar52. doi: 10.1091/mbc.E24-08-0382. Epub 2025 Mar 5.
PMID: 40042941
A functional map of phosphoprotein phosphatase regulation identifies an evolutionary conserved reductase for the catalytic metal ions.
Meeusen B, Ambjorn SM, Veis J, Riley RC, Vit G, Brauer BL, Moller MH, Greiner EC, Chan CB, Weisser MB, Garvanska DH, Zhu H, Davey NE, Kettenbach AN, Ogris E, Nilsson J
bioRxiv. 2025 Feb 16; pii: 2025.02.12.637884. doi: 10.1101/2025.02.12.637884. Epub 2025 Feb 16.
PMID: 39990307
An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity.
Kucharski TJ, Vlasac IM, Lyalina T, Higgs MR, Christensen BC, Bechstedt S, Compton DA
Cell Rep. 2025 Feb 25;44(2):115317. doi: 10.1016/j.celrep.2025.115317. Epub 2025 Feb 18.
PMID: 39970043
The LC3-interacting region of NBR1 is a protein interaction hub enabling optimal flux.
North BJ, Ohnstad AE, Ragusa MJ, Shoemaker CJ
J Cell Biol. 2025 Apr 7;224(4) doi: 10.1083/jcb.202407105. Epub 2025 Feb 10.
PMID: 39928048
Wnt signaling inhibits casein kinase 1α activity by modulating its interaction with protein phosphatase 2A.
Shen C, Lu W, Merugu SB, Bharti A, Afify SM, Schnitkey L, Wynn DT, Yang F, Rohwetter TM, Nayak A, Bunnag N, Cywiak C, Tang HY, Harris BT, Albanese C, Ihemelandu C, Cobb MH, Kettenbach A, Lee E, Ahmed Y, Robbins DJ
Cell Rep. 2025 Feb 25;44(2):115274. doi: 10.1016/j.celrep.2025.115274. Epub 2025 Feb 6.
PMID: 39908140
Coronin1A Regulates the Trafficking of Alpha Synuclein in Microglia.
Biggs KE, Fikse EN, Anderson FL, Kettenbach AN, Havrda MC
J Neurosci. 2025 Mar 12;45(11) doi: 10.1523/JNEUROSCI.1337-24.2025. Epub 2025 Mar 12.
PMID: 39837661
Oxidative Phosphorylation Is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer.
Tau S, Chamberlin MD, Yang H, Marotti JD, Muskus PC, Roberts AM, Carmichael MM, Cressey L, Dragnev CPC, Demidenko E, Hampsch RA, Soucy SM, Kolling FW, Samkoe KS, Alvarez JV, Kettenbach AN, Miller TW
Cancer Res. 2025 Mar 14;85(6):1145-1161. doi: 10.1158/0008-5472.CAN-24-1204.
PMID: 39777474
Inhibiting the Cholesterol Storage Enzyme ACAT1/SOAT1 in Aging Apolipoprotein E4 Mice Alters Their Brains' Inflammatory Profiles.
Huynh TN, Fikse EN, De La Torre AL, Havrda MC, Chang CCY, Chang TY
Int J Mol Sci. 2024 Dec 21;25(24) doi: 10.3390/ijms252413690. Epub 2024 Dec 21.
PMID: 39769453
A Compensated Clock: Temperature and Nutritional Compensation Mechanisms Across Circadian Systems.
Stevenson EL, Mehalow AK, Loros JJ, Kelliher CM, Dunlap JC
Bioessays. 2025 Mar;47(3):e202400211. doi: 10.1002/bies.202400211. Epub 2024 Dec 18.
PMID: 39696884
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