Recent Publications

Henry Higgs.
Higgs H
Curr Biol. 2023 May 22;33(10):R380-R382. doi: 10.1016/j.cub.2023.04.040.
PMID: 37220723

Substrate and phosphorylation site selection by phosphoprotein phosphatases.
Nguyen H, Kettenbach AN
Trends Biochem Sci. 2023 May 10; pii: S0968-0004(23)00088-9. doi: 10.1016/j.tibs.2023.04.004. Epub 2023 May 10.
PMID: 37173206

ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia.
Li H, Huynh TN, Duong MT, Gow JG, Chang CCY, Chang TY
Int J Mol Sci. 2023 Mar 15;24(6) doi: 10.3390/ijms24065616. Epub 2023 Mar 15.
PMID: 36982689

Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity.
Harned TC, Stan RV, Cao Z, Chakrabarti R, Higgs HN, Chang CCY, Chang TY
Int J Mol Sci. 2023 Mar 14;24(6) doi: 10.3390/ijms24065525. Epub 2023 Mar 14.
PMID: 36982602

The ERK activator, BCI, inhibits ciliogenesis and causes defects in motor behavior, ciliary gating, and cytoskeletal rearrangement.
Dougherty LL, Dutta S, Avasthi P
Life Sci Alliance. 2023 Jun;6(6) doi: 10.26508/lsa.202301899. Epub 2023 Mar 13.
PMID: 36914265

Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets.
Tahti EF, Blount JM, Jackson SN, Gao M, Gill NP, Smith SN, Pederson NJ, Rumph SN, Struyvenberg SA, Mackley IGP, Madden DR, Amacher JF
Protein Sci. 2023 Apr;32(4):e4611. doi: 10.1002/pro.4611.
PMID: 36851847

Initial ciliary assembly in Chlamydomonas requires Arp2/3 complex-dependent endocytosis.
Bigge BM, Rosenthal NE, Avasthi P
Mol Biol Cell. 2023 Apr 1;34(4):ar24. doi: 10.1091/mbc.E22-09-0443. Epub 2023 Feb 8.
PMID: 36753382

Lithium-induced ciliary lengthening sparks Arp2/3 complex-dependent endocytosis.
Bigge BM, Dougherty LL, Avasthi P
Mol Biol Cell. 2023 Apr 1;34(4):ar26. doi: 10.1091/mbc.E22-06-0219. Epub 2023 Feb 8.
PMID: 36753380

PI3P regulates multiple stages of membrane fusion.
Orr A, Wickner W
Mol Biol Cell. 2023 Mar 1;34(3):ar17. doi: 10.1091/mbc.E22-10-0486. Epub 2023 Feb 3.
PMID: 36735517

Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets.
Tahti EF, Blount JM, Jackson SN, Gao M, Gill NP, Smith SN, Pederson NJ, Rumph SN, Struyvenberg SA, Mackley IGP, Madden DR, Amacher JF
bioRxiv. 2023 Jan 10; pii: 2022.12.31.522388. doi: 10.1101/2022.12.31.522388. Epub 2023 Jan 10.
PMID: 36711692

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