Suppression of haptoglobin and loss of striatal neurons in mice chronically exposed to chlorpyrifos-contaminated drinking water.
Fikse E, Anderson F, Cho S, Landry J, Carloni E, Biggs K, Paul K, Daley T, Chang TY, Kettenbach A, Havrda MC
Toxicol Sci. 2026 Mar 2;209(3) pii: kfag012. doi: 10.1093/toxsci/kfag012.
PMID: 41668286
The clinical missense variant E282K in PPP3CA/calcineurin shifts substrate dephosphorylation by altering active site recruitment.
Shirakawa KT, Parikh T, Machado LESF, Poimenidou G, Nguyen HT, Dell'Acqua ML, Kettenbach AN, Page R, Peti W
Nat Commun. 2026 Feb 16; doi: 10.1038/s41467-026-69535-5. Epub 2026 Feb 16.
PMID: 41698888
Convergent strategies for nanobody-mediated inhibition of an epoxide hydrolase.
Simard AR, Taher NM, Beauchemin KS, Mishra AK, Hederman AP, Hampton TH, Vasylieva N, Morisseau C, Ackerman ME, Madden DR
bioRxiv. 2026 Feb 10; pii: 2026.02.09.704437. doi: 10.64898/2026.02.09.704437. Epub 2026 Feb 10.
PMID: 41726885
A daily cycle of White Collar Complex dephosphorylation sustains circadian rhythmicity in Neurospora.
Wang B, Zhou X, Loros JJ, Dunlap JC
Proc Natl Acad Sci U S A. 2026 Feb 10;123(6):e2525126123. doi: 10.1073/pnas.2525126123. Epub 2026 Feb 6.
PMID: 41650222
Countervailing effects of cyclin isoforms A and B during mitosis.
Bural S, Compton DA
bioRxiv. 2026 Feb 2; pii: 2026.01.30.702807. doi: 10.64898/2026.01.30.702807. Epub 2026 Feb 2.
PMID: 41684933
Regulation of the formin INF2 by actin monomers and calcium/calmodulin.
Lee M, Jalmukhambetova A, Burgin TE, Higgs HN
J Cell Biol. 2026 Feb 2;225(2) pii: e202507147. doi: 10.1083/jcb.202507147. Epub 2026 Jan 7.
PMID: 41498749
Mutant knock-in mice display enhanced susceptibility to pure prion protein fibrils.
Walsh DJ, Standke H, Kraus A, Watts JC, Supattapone S
J Gen Virol. 2026 Feb;107(2) doi: 10.1099/jgv.0.002219.
PMID: 41642644
Sequence Engineering at Non-motif Modulator Residues Yields a Peptide That Effectively Targets a Single PDZ Protein in a Disease-relevant Cellular Context.
Amacher JF, Cushing PR, Vouilleme L, Cullati SN, Deng B, Gerber SA, Boisguerin P, Madden DR
J Mol Biol. 2026 Feb 1;438(3):169597. doi: 10.1016/j.jmb.2025.169597. Epub 2025 Dec 17.
PMID: 41419168
Cell-Autonomous and Systemic Circadian Regulation of Gene Expression in Adipocytes.
Worthen JM, Frederick AM, Dumesic PA, Loros JJ, Dunlap JC
bioRxiv. 2026 Jan 26; pii: 2026.01.24.701487. doi: 10.64898/2026.01.24.701487. Epub 2026 Jan 26.
PMID: 41659457
Genome-wide screens identify core regulators of cell surface prion protein expression.
Beauchemin KS, Supattapone S
Sci Rep. 2026 Jan 21;16(1):5895. doi: 10.1038/s41598-026-37137-2. Epub 2026 Jan 21.
PMID: 41565761
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