Interaction of IRS2 with PLK1 protects cells from mitotic stress.
Lee JS, Bui QT, Jo M, Morgan JS, Nasa I, Kettenbach AN, Shaw LM
Cell Death Dis. 2026 Apr 8; doi: 10.1038/s41419-026-08706-0. Epub 2026 Apr 8.
PMID: 41951610
The Yersinia pestis effector YopM binds the human pyrin death domain to inhibit inflammasome activation and effector-triggered immunity.
Mwaura BW, Simard AR, Pettis ML, Liu A, Madden DR, Bliska JB
bioRxiv. 2026 Mar 25; pii: 2026.02.25.707193. doi: 10.64898/2026.02.25.707193. Epub 2026 Mar 25.
PMID: 41929001
FAM122A inhibition of PP2A-B55 through a bipartite binding mechanism.
Benavides-Puy I, Vigneron S, Kettenbach AN, Lorca T, Nilsson J
bioRxiv. 2026 Mar 25; pii: 2026.03.24.713894. doi: 10.64898/2026.03.24.713894. Epub 2026 Mar 25.
PMID: 41928937
Suppression of haptoglobin and loss of striatal neurons in mice chronically exposed to chlorpyrifos-contaminated drinking water.
Fikse E, Anderson F, Cho S, Landry J, Carloni E, Biggs K, Paul K, Daley T, Chang TY, Kettenbach A, Havrda MC
Toxicol Sci. 2026 Mar 2;209(3) doi: 10.1093/toxsci/kfag012.
PMID: 41668286
The clinical missense variant E282K in PPP3CA/calcineurin shifts substrate dephosphorylation by altering active site recruitment.
Shirakawa KT, Parikh T, Machado LESF, Poimenidou G, Nguyen HT, Dell'Acqua ML, Kettenbach AN, Page R, Peti W
Nat Commun. 2026 Feb 16;17(1) doi: 10.1038/s41467-026-69535-5. Epub 2026 Feb 16.
PMID: 41698888
A daily cycle of White Collar Complex dephosphorylation sustains circadian rhythmicity in Neurospora.
Wang B, Zhou X, Loros JJ, Dunlap JC
Proc Natl Acad Sci U S A. 2026 Feb 10;123(6):e2525126123. doi: 10.1073/pnas.2525126123. Epub 2026 Feb 6.
PMID: 41650222
Countervailing effects of cyclin isoforms A and B during mitosis.
Bural S, Compton DA
bioRxiv. 2026 Feb 2; pii: 2026.01.30.702807. doi: 10.64898/2026.01.30.702807. Epub 2026 Feb 2.
PMID: 41684933
Regulation of the formin INF2 by actin monomers and calcium/calmodulin.
Lee M, Jalmukhambetova A, Burgin TE, Higgs HN
J Cell Biol. 2026 Feb 2;225(2) pii: e202507147. doi: 10.1083/jcb.202507147. Epub 2026 Jan 7.
PMID: 41498749
Mutant knock-in mice display enhanced susceptibility to pure prion protein fibrils.
Walsh DJ, Standke H, Kraus A, Watts JC, Supattapone S
J Gen Virol. 2026 Feb;107(2) doi: 10.1099/jgv.0.002219.
PMID: 41642644
Sequence Engineering at Non-motif Modulator Residues Yields a Peptide That Effectively Targets a Single PDZ Protein in a Disease-relevant Cellular Context.
Amacher JF, Cushing PR, Vouilleme L, Cullati SN, Deng B, Gerber SA, Boisguerin P, Madden DR
J Mol Biol. 2026 Feb 1;438(3):169597. doi: 10.1016/j.jmb.2025.169597. Epub 2025 Dec 17.
PMID: 41419168
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