Welcome to the Obar Laboratory in the Department of Microbiology and Immunology at the Geisel School of Medicine at Dartmouth. We are located in the Borwell Building of Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire. Our laboratory is focused on elucidating the mechanisms by which inflammatory leukocytes are recruited to and activated in the lungs during respiratory infections to mediate either resistance to infection, in most cases, or lead to tissue immunopathology if they are inappropriately recruited to or activated in the tissue.
Obar Laboratory
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Publications
Pedal to the metal: iron regulation of Aspergillus fumigatus protease production.
McGee AP, Obar JJ
Am J Respir Cell Mol Biol. 2026 Feb 1;74(2):152-154. doi: 10.1165/rcmb.2025-0506ED.
PMID: 41071164
Reply to nurture over nature in fate decisions of antigen-specific CD8(+) T cell clones from an endogenous repertoire.
Abdullah L, Obar JJ, Huang YH
Immunity. 2025 Oct 14;58(10):2357-2358. doi: 10.1016/j.immuni.2025.09.006.
PMID: 41092891
TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation.
Thomas SM, McGee AP, Vielma TE, Ankley LM, Rapp AW, Conner KN, et al.
bioRxiv. 2025 May 1; pii: 2024.09.04.611226. doi: 10.1101/2024.09.04.611226. Epub 2025 May 1.
PMID: 39282428
Contact Us
Joshua J. Obar, Ph.D
Professor of Microbiology & Immunology
Director of Molecular & Cellular Biology (MCB) Graduate Program
Phone: 603-646-5383
Email: Joshua.J.Obar@Dartmouth.EDU
Social Media Handles:
X: @ObarLab
BlueSky: @obarlab.bsky.social
Mailing Address:
Geisel School of Medicine at Dartmouth
Department of Microbiology & Immunology
Borwell Building - 650W
1 Medical Center Drive
Lebanon, NH 03756
Positions Available
Interested MCB graduate students, post-doctoral fellows, and research scientists should contact Dr. Obar via email to discuss potential positions in the laboratory.
For prospective graduate students, please see the Dartmouth MCB Program web page for application information.