Publications

Nutritional Heterogeneity Among <i>Aspergillus fumigatus</i> Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner.
Ries LNA, Steenwyk JL, de Castro PA, de Lima PBA, Almeida F, de Assis LJ, Manfiolli AO, Takahashi-Nakaguchi A, Kusuya Y, Hagiwara D, Takahashi H, Wang X, Obar JJ, Rokas A, Goldman GH
Front Microbiol. 2019;10:854. doi: 10.3389/fmicb.2019.00854. Epub 2019 Apr 24.
PMID: 31105662

Secondary Bacterial Pneumonia by Staphylococcus aureus Following Influenza A Infection Is SaeR/S Dependent.
Borgogna TR, Hisey B, Heitmann E, Obar JJ, Meissner N, Voyich JM
J Infect Dis. 2018 Jul 24;218(5):809-813. doi: 10.1093/infdis/jiy210.
PMID: 29668950

Host-Derived Leukotriene B<sub>4</sub> Is Critical for Resistance against Invasive Pulmonary Aspergillosis.
Caffrey-Carr AK, Hilmer KM, Kowalski CH, Shepardson KM, Temple RM, Cramer RA, Obar JJ
Front Immunol. 2017;8:1984. doi: 10.3389/fimmu.2017.01984. Epub 2018 Jan 11.
PMID: 29375586

Type III interferon is a critical regulator of innate antifungal immunity.
Espinosa V, Dutta O, McElrath C, Du P, Chang YJ, Cicciarelli B, Pitler A, Whitehead I, Obar JJ, Durbin JE, Kotenko SV, Rivera A
Sci Immunol. 2017 Oct 6;2(16) pii: eaan5357. doi: 10.1126/sciimmunol.aan5357.
PMID: 28986419

Interleukin 1α Is Critical for Resistance against Highly Virulent Aspergillus fumigatus Isolates.
Caffrey-Carr AK, Kowalski CH, Beattie SR, Blaseg NA, Upshaw CR, Thammahong A, Lust HE, Tang YW, Hohl TM, Cramer RA, Obar JJ
Infect Immun. 2017 Dec;85(12) pii: e00661-17. doi: 10.1128/IAI.00661-17. Epub 2017 Nov 17.
PMID: 28947643

<i>Aspergillus fumigatus</i> Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.
Thammahong A, Caffrey-Card AK, Dhingra S, Obar JJ, Cramer RA
MBio. 2017 Apr 25;8(2) pii: e00056-17. doi: 10.1128/mBio.00056-17. Epub 2017 Apr 25.
PMID: 28442603

Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression.
Beattie SR, Mark KMK, Thammahong A, Ries LNA, Dhingra S, Caffrey-Carr AK, Cheng C, Black CC, Bowyer P, Bromley MJ, Obar JJ, Goldman GH, Cramer RA
PLoS Pathog. 2017 Apr;13(4):e1006340. doi: 10.1371/journal.ppat.1006340. Epub 2017 Apr 19.
PMID: 28423062

Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence.
Kowalski CH, Beattie SR, Fuller KK, McGurk EA, Tang YW, Hohl TM, Obar JJ, Cramer RA Jr
MBio. 2016 Sep 20;7(5) pii: e01515-16. doi: 10.1128/mBio.01515-16. Epub 2016 Sep 20.
PMID: 27651366

Alarmin(g) the innate immune system to invasive fungal infections.
Caffrey AK, Obar JJ
Curr Opin Microbiol. 2016 Aug;32:135-143. doi: 10.1016/j.mib.2016.06.002. Epub 2016 Jun 27.
PMID: 27351354

New advances in invasive aspergillosis immunobiology leading the way towards personalized therapeutic approaches.
Obar JJ, Hohl TM, Cramer RA
Cytokine. 2016 Aug;84:63-73. doi: 10.1016/j.cyto.2016.05.015. Epub 2016 May 30.
PMID: 27253487


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