Publications
Regulation of Syk activity by antiviral adaptor MAVS in FcεRI signaling pathway.
Kawakami Y, Kimura M, Widjaja C, Kasakura K, Ando T, Kawakami Y, Obar JJ, Kawakami T
Front Allergy. 2023;4:1098474. doi: 10.3389/falgy.2023.1098474. Epub 2023 Apr 24.
PMID: 37168500
Coinfections in the lung: How viral infection creates a favorable environment for bacterial and fungal infections.
Obar JJ, Shepardson KM
PLoS Pathog. 2023 May;19(5):e1011334. doi: 10.1371/journal.ppat.1011334. Epub 2023 May 4.
PMID: 37141196
Postinfluenza Environment Reduces Aspergillus fumigatus Conidium Clearance and Facilitates Invasive Aspergillosis In Vivo.
Liu KW, Grau MS, Jones JT, Wang X, Vesely EM, James MR, Gutierrez-Perez C, Cramer RA, Obar JJ
mBio. 2022 Dec 20;13(6):e0285422. doi: 10.1128/mbio.02854-22. Epub 2022 Nov 15.
PMID: 36377895
MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus.
Wang X, Cunha C, Grau MS, Robertson SJ, Lacerda JF, Campos A Jr, Lagrou K, Maertens J, Best SM, Carvalho A, Obar JJ
J Immunol. 2022 Jul 15;209(2):346-353. doi: 10.4049/jimmunol.2100759. Epub 2022 Jun 24.
PMID: 35750336
Host Lung Environment Limits Aspergillus fumigatus Germination through an SskA-Dependent Signaling Response.
Kirkland ME, Stannard M, Kowalski CH, Mould D, Caffrey-Carr A, Temple RM, Ross BS, Lofgren LA, Stajich JE, Cramer RA, Obar JJ
mSphere. 2021 Dec 22;6(6):e0092221. doi: 10.1128/msphere.00922-21. Epub 2021 Dec 8.
PMID: 34878292
Editorial overview: Niche-specific and species-specific host-fungal interactions - how do they impact human health?
Drummond RA, Obar JJ
Curr Opin Microbiol. 2021 Dec;64:162-165. doi: 10.1016/j.mib.2021.10.003. Epub 2021 Oct 22.
PMID: 34696987
The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During Aspergillus fumigatus Airway Infection.
Ralph BA, Lehoux M, Ostapska H, Snarr BD, Caffrey-Carr AK, Fraser R, Saleh M, Obar JJ, Qureshi ST, Sheppard DC
Front Immunol. 2021;12:675294. doi: 10.3389/fimmu.2021.675294. Epub 2021 Jul 12.
PMID: 34322116
Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype.
Jones JT, Liu KW, Wang X, Kowalski CH, Ross BS, Mills KAM, Kerkaert JD, Hohl TM, Lofgren LA, Stajich JE, Obar JJ, Cramer RA
mSphere. 2021 Feb 17;6(1) doi: 10.1128/mSphere.01250-20. Epub 2021 Feb 17.
PMID: 33597172
MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.
Wang X, Caffrey-Carr AK, Liu KW, Espinosa V, Croteau W, Dhingra S, Rivera A, Cramer RA, Obar JJ
J Immunol. 2020 Dec 1;205(11):3058-3070. doi: 10.4049/jimmunol.2000802. Epub 2020 Oct 21.
PMID: 33087405
Sensing the threat posed by Aspergillus infection.
Obar JJ
Curr Opin Microbiol. 2020 Dec;58:47-55. doi: 10.1016/j.mib.2020.08.004. Epub 2020 Sep 6.
PMID: 32898768