Publications

Myeloid Cell States in Influenza-Associated Pulmonary Aspergillosis Are Shaped by Iron Overload and Metabolic Reprogramming.
Grau MS, Jackson BP, Ringelberg C, Kolling FW, Deepe GS, Cramer RA, Obar JJ
bioRxiv. 2026 Apr 25; pii: 2026.04.22.720189. doi: 10.64898/2026.04.22.720189. Epub 2026 Apr 25.
PMID: 42079193

Pedal to the metal: iron regulation of Aspergillus fumigatus protease production.
McGee AP, Obar JJ
Am J Respir Cell Mol Biol. 2026 Feb 1;74(2):152-154. doi: 10.1165/rcmb.2025-0506ED.
PMID: 41071164

Reply to nurture over nature in fate decisions of antigen-specific CD8(+) T cell clones from an endogenous repertoire.
Abdullah L, Obar JJ, Huang YH
Immunity. 2025 Oct 14;58(10):2357-2358. doi: 10.1016/j.immuni.2025.09.006.
PMID: 41092891

TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation.
Thomas SM, McGee AP, Vielma TE, Ankley LM, Rapp AW, Conner KN, LeSage F, Tanner CD, Scheeres EC, Obar JJ, Olive AJ
bioRxiv. 2025 May 1; pii: 2024.09.04.611226. doi: 10.1101/2024.09.04.611226. Epub 2025 May 1.
PMID: 39282428

Recent developments in Aspergillus fumigatus research: diversity, drugs, and disease.
Kordana N, Johnson A, Quinn K, Obar JJ, Cramer RA
Microbiol Mol Biol Rev. 2025 Mar 27;89(1):e0001123. doi: 10.1128/mmbr.00011-23. Epub 2025 Feb 10.
PMID: 39927770

The endogenous antigen-specific CD8(+) T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments.
Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Musial SC, Kolling FW, Obar JJ, Rosato PC, Ackerman ME, Song L, McKenna A, Huang YH
Immunity. 2025 Mar 11;58(3):601-615.e9. doi: 10.1016/j.immuni.2025.02.001. Epub 2025 Feb 27.
PMID: 40020673

Coinfections in the lung: How viral infection creates a favorable environment for bacterial and fungal infections.
Obar JJ, Shepardson KM
PLoS Pathog. 2023 May;19(5):e1011334. doi: 10.1371/journal.ppat.1011334. Epub 2023 May 4.
PMID: 37141196

Regulation of Syk activity by antiviral adaptor MAVS in FcεRI signaling pathway.
Kawakami Y, Kimura M, Widjaja C, Kasakura K, Ando T, Kawakami Y, Obar JJ, Kawakami T
Front Allergy. 2023;4:1098474. doi: 10.3389/falgy.2023.1098474. Epub 2023 Apr 24.
PMID: 37168500

Postinfluenza Environment Reduces Aspergillus fumigatus Conidium Clearance and Facilitates Invasive Aspergillosis In Vivo.
Liu KW, Grau MS, Jones JT, Wang X, Vesely EM, James MR, Gutierrez-Perez C, Cramer RA, Obar JJ
mBio. 2022 Dec 20;13(6):e0285422. doi: 10.1128/mbio.02854-22. Epub 2022 Nov 15.
PMID: 36377895

MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus.
Wang X, Cunha C, Grau MS, Robertson SJ, Lacerda JF, Campos A Jr, Lagrou K, Maertens J, Best SM, Carvalho A, Obar JJ
J Immunol. 2022 Jul 15;209(2):346-353. doi: 10.4049/jimmunol.2100759. Epub 2022 Jun 24.
PMID: 35750336

 
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