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KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection.
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CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors.
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J Immunother Cancer. 2025 Feb 11;13(2) doi: 10.1136/jitc-2024-009994. Epub 2025 Feb 11.
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Depletion of conventional CD4(+) T cells is required for robust priming and dissemination of tumor antigen-specific CD8(+) T cells in the setting of anti-CD4 therapy.
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J Immunother Cancer. 2024 Nov 9;12(11) doi: 10.1136/jitc-2024-010170. Epub 2024 Nov 9.
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Anesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect.
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Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection.
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bioRxiv. 2024 Mar 27; pii: 2024.03.21.586160. doi: 10.1101/2024.03.21.586160. Epub 2024 Mar 27.
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Anesthetic oxygen use and sex are critical factors in the FLASH sparing effect.
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In the right place at the right time: tissue-resident memory T cells in immunity to cancer.
Ramirez DE, Mohamed A, Huang YH, Turk MJ
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Toward high-throughput engineering techniques for improving CAR intracellular signaling domains.
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Cell type-specific Interaction Analysis using Doublets in scRNA-seq (CIcADA).
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