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Rachel A. Brog, Ph.D.

MCB alumna

Rachel first became interested in research during my undergraduate studies at Brigham Young University where she was working to characterize novel biomarker for immunotherapy. This is when her love for the jargon-filled, acronym-heavy field of immunology commenced. After graduating with a BS in Molecular Biology at BYU and entry into the MCB program at Dartmouth, Rachel joined the Huang lab in June of 2017 and defended her PhD in 2021. Rachel's research in the Huang lab focused on engineering improved antigen recognition by chimeric antigen receptors (CARs) and expression of immune modulators that transform the tumor microenvironment from immune suppressive to immune activating. She is a co-inventor on a patent application, co-founded the Dartmouth Biotech club and served as Guarini Housing representative. Rachel is currently a scientist at Thunder Biotech in Utah. As a Utah native, she loves riding ATVs in the Rockies and hitting up the local national parks. She also enjoys baking, snowboarding, and playing soccer.

Publications

Butler SE*, Brog RA*, Chang CH, Sentman CL, Huang YH, Ackerman ME. Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30. Cancer Immunol Immunother. 2021 doi: 10.1007/s00262-021-02971-y. PMID: 34046711

 

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