Supporting Publications

Ordered by year of publication:

2018

  • Tan, Q, et al.  "Activation-induced cytidine deaminase deficiency accelerates autoimmune diabetes in NOD mice."  JCI Insight, 2018; 3(1):e95882. https://
    doi.org/10.1172/jci.insight.95882.

2017

  • Chen, G, et al. “Comparison of RELM[1] and RELM  Single- and Double-Gene-Deficient Mice Reveals that RELM[1] Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection.”  Infection and Immunity, 84:1100 –1111. doi:10.1128/IAI.01479-15.  (2017)
  • Furuya, Y, et al. “Defective anti-polysaccharide IgG vaccine responses in IgA deficient mice.”  Vaccine  (2017)
  • Li, Y. et al. “Nucleotide-binding oligomerization domain-containing protein 2 (Nod2) modulates T1DM susceptibility by gut microbiota.”  Journal of Autoimmunity, (2017), http://dx.doi.org/10.1016/j.jaut.2017.05.007
  • Otterpohl, K, et al. “Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk.”  PLoS ONE, 12(3): e0172247.  doi:10.1371/journal.pone.0172247  (2016)
  • Quintar, A, et al. “Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis.”  Integrative Physiology, 2017;120:1789-1799. DOI: 10.1161/ CIRCRESAHA.117.310739
  • Steinberg, S, et al. “Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors.”  Cancer Research; 77(7) April 1, 2017

2016

  • Bae, H, et al. “Chronic Expression of Interferon-Gamma Leads to Murine Autoimmune Cholangitis With a Female Predominance.”  Hepatology, VOL. 64, NO. 4, 2016
  • Bai, G, et al. “Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation.” PLoS Genetics 12(1): e1005787. doi:10.1371/journal.pgen.1005787  (2016)
  • Bhattacharyya, S., et al. “Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.”  Scientific Reports, 6, 20727; doi: 10.1038/srep20727 (2016)
  • Byrne, K, et al. “CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer.”  Cell Reports, 15, 1–14 June 21, 2016
  • Byrne, K, et al. “CSF-1R–Dependent Lethal Hepatotoxicity When Agonistic CD40 Antibody Is Given before but Not after Chemotherapy.”  Journal if Immunology, May 23, 2016, doi:10.4049/jimmunol.1600146
  • Crittenden, M, et al. “Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy.”  Oncotarget, Vol. 7, No. 48 (2016)
  • Evans, R, et al. “Lack of immunoediting in murine pancreatic cancer reversed with neoantigen.”  JCI Insight. 2016;1(14):e88328. doi:10.1172/jci.insight.88328
  • Gillespie AL, et al. “Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection.” PLoS Pathog 12(2): e1005419. doi:10.1371/journal. ppat.1005419 (2016)
  • Lohr, K, et al. “Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals.”  Toxicological Sciences, 2016, Vol. 153, No. 1
  • Rastad, J. & Green, W. “Myeloid-derived suppressor cells in murine AIDS inhibit B-cell responses in part via soluble mediators including reactive oxygen and nitrogen species, andTGF-β.” Virology 499(2016)9–22
  • Saddawi-Konefka et al., “Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.” Cell Reports 16, 2348–2358 August 30, 2016
  • Sheen, MR, et al. “Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer.”  Oncogenesis (2016) 5, e267; doi:10.1038/oncsis.2016.65
  • Shimizu, T., et al. “Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis.”  Journal of Experimental Medicine (2016)
  • Tabor, D, et al. “Estrogen receptor alpha promotes lupus in (NZB NZW)F1 mice in a B cell intrinsic manner.”  Clinical Immunology (2016), doi:10.1016/j.clim.2016.10.011
  • van der Heijden, M, et al. “Bcl-2 is a critical mediator of intestinal transformation.”  Nature Communications 7:10916, DOI: 10.1038/ncomms10916 (2016)

2015

  • Krishnaswamy, J.K. et al, "Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration," Proceedings of the National Academy of Sciences, March 10, 2015 vol. 112 no. 10 3056-3061

http://www.pnas.org/content/112/10/3056

  • Melville, K. M. et al, "Effects of deletion of ER-alpha in osteoblast-lineage cells on bone mass and adaptation to mechanical loading differs in female and male mice," Journal of Bone and Mineral Research, 1523-4681, 10.1002/jbmr.2488

http://dx.doi.org/10.1002/jbmr.2488

2014

  • Han, Hongwei et al "Thymic stromal lymphopoietin–mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis," Journal of Clinical Investigation, 2014;124(12):5442–5452. doi:10.1172/JCI77798.

http://www.jci.org/articles/view/77798

  • Hodge, D. et al  "IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice," Journal of Autoimmunity, Available online 28 February 2014, ISSN 0896-8411, http://dx.doi.org/10.1016/j.jaut.2014.02.003.

http://www.sciencedirect.com/science/article/pii/S0896841114000420

  • Mishra et al., "The Histone Methyltransferase Activity of MLL1 Is Dispensable for Hematopoiesis and Leukemogenesis," Cell Reports (2014), http://dx.doi.org/10.1016/j.celrep.2014.04.015

http://www.sciencedirect.com/science/article/pii/S2211124714003027

  • Tan, Q. et al.  "IRAK-M deficiency promotes the development of T1DM in NOD mice."  Diabetes, Published online before print April 2, 2014, doi: 10.2337/db13-1504

http://diabetes.diabetesjournals.org/content/early/2014/03/31/db13-1504.short

2013

  • Prince, J. et al.  "Multiparametric Analysis of Host Response to Murine Cytomegalovirus in MHC Class I–Disparate Mice Reveals Primacy of Dk-Licensed Ly49G2+ NK Cells in Viral Control."  J Immunol published September 25, 2013, doi:10.4049/jimmunol.1301388

http://www.jimmunol.org/content/early/2013/09/25/jimmunol.1301388

  • Li, B. E. et al. "Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells." Blood 2013;122(12):2039-2046.

http://bloodjournal.hematologylibrary.org/content/122/12/2039.short

  • O'Connor, M. A. et al.  "Use of IRF-3 and/or IRF-7 Knockout Mice To Study Viral Pathogenesis: Lessons from a Murine Retrovirus-Induced AIDS Model."  Journal of Virology.  February 2014 vol. 88 no. 4 2349-2353.  Published ahead of print 11 December 2013

http://jvi.asm.org/content/88/4/2349.short

  • Saligrama, N. et al.  "Histamine H2 receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis."  The FASEB Journal, article fj.13-239939. Published online December 26, 2013.

http://www.fasebj.org/content/early/2013/12/23/fj.13-239939.short

  • Saligrama, N. et al.  "Systemic Lack of Canonical Histamine Receptor Signaling Results in Increased Resistance to Autoimmune Encephalomyelitis."  J Immunol, July 15, 2013 vol. 191 no. 2 614-622

http://www.jimmunol.org/content/191/2/614.short

  • Wang Y,  et al. (2013) Role of IRAK-M in Alcohol Induced Liver Injury. PLoS ONE 8(2): e57085. doi:10.1371/
    journal.pone.0057085

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057085

2012

  • Lundgren, A., et al.  “Rapid discrimination of MHC class I and killer cell lectin-like receptor allele variants by high-resolution melt analysis.”  Immunogenetics (2012) 64:633–640

http://link.springer.com/article/10.1007%2Fs00251-012-0630-4

  • Scarlett, U., et al.  “Ovarian cancer progression is controlled by phenotypic changes in dendritic cells.”  Journal of Experimental Medicine 2012; Vol. 209 No. 3 495-506

http://jem.rupress.org/content/209/3/495.long

  • Cripps, J. et al.,  “Liver inflammation in a mouse model of Th1 hepatitis despite the absence of invariant NKT cells or the Th1 chemokine receptors CXCR3 and CCR5.”  Laboratory Investigation (2012) 92, 1461–1471

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460069/

  • Gorham, J. et al.,  “1 + 1 = 3: Development and Validation of a SNP-Based Algorithm to Identify Genetic Contributions from Three Distinct Inbred Mouse Strains.”  Journal of Biomolecular Techniques 23:136–146

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442358/

  • Shah, H. et al.,  “Type II NKT cells facilitate Alum-sensing and humoral immunity.”  Journal of Leukocyte Biology (2012) Volume 92

http://www.jleukbio.org/content/92/4/883.long

  • Colpitts, S., et al.  “Cutting Edge: The Role of IFN-a Receptor and MyD88 Signaling in Induction of IL-15 Expression In Vivo.”  Journal of Immunology 2012;188;2483-2487

http://www.jimmunol.org/content/188/6/2483.long

  • Blutt, S., et al.  “IgA is important for clearance and critical for protection from rotovirus infection.”  Mucosal Immunology 2012

http://www.nature.com/mi/journal/v5/n6/full/mi201251a.html

  • Potula, H., et al.  “Cyclin-Dependent Kinase Inhibitor Cdkn2c Deficiency Promotes B1a Cell Expansion and Autoimmunity in a Mouse Model of Lupus.”  Journal of Immunology 2012; 189:2931-2940

http://www.jimmunol.org/content/189/6/2931.long

  • Fang, C-M., et al.  “Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response.”  Genes and Immunity (2012) 13, 421–430

http://www.nature.com/gene/journal/v13/n5/full/gene201210a.html

  • Miller, H., et al.  “Early Control of Mycobacterium tuberculosis Infection Requires il12rb1 Expression by rag1-Dependent Lineages.”  Infection and Immunity 2012, 80(11):3828.

http://iai.asm.org/content/80/11/3828.long

  • Stan, R. et al., “The Diaphragms of Fenestrated Endothelia:  Gatekeepers of Vascular Permeability and Blood Composition.”  Developmental Cell (2012) 23, 1203–1218

http://www.sciencedirect.com/science/article/pii/S1534580712005230

  • Wang, Y., et al.  “Role of IRAK-M in Alcohol Induced Liver Injury.”  PLoS ONE 8(2): e57085. doi:10.1371/ journal.pone.0057085

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578822/

2011

  • Gogliotti, R., et al.  “Characterization of a commonly used mouse model of SMA reveals increased seizure susceptibility and heightened fear response in FVB/N mice.”  Neurobiology of Disease 43 (2011) 142–151

http://www.sciencedirect.com/science/article/pii/S0969996111000738

  • Pasieka, T., et al.  “Bioluminescent Imaging Reveals Divergent Viral Pathogenesis in Two Strains of Stat1-Deficient Mice, and in aßc Interferon Receptor-Deficient Mice.”  PLoS ONE 6(9): e24018. doi:10.1371/journal.pone.0024018

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168466/

2010

  • Trask, H., et al.  “Introducing DartMouse: The Mouse Speed Congenic Facility at Dartmouth Medical School.”  Journal of Biomolecular Techniques (2010), 21(3 Suppl): S70.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918122/

  • Aktan, I., et al.  “Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function.”  Journal of Immunology 2010; 185; 144-156

http://www.jimmunol.org/content/185/1/144.long