Role of the cGAS-STING pathway in systemic and organ-specific diseases.
Skopelja-Gardner S, An J, Elkon KB.
Nature Reviews Nephrology
PMID: 35732833
Acute skin exposure to ultraviolet light triggers neutrophil-mediated kidney inflammation.
Skopelja-Gardner S, Tai J, Sun X, Tanaka L, Kuchenbecker JA, Snyder JM, Kubes P, Mustelin T, Elkon KB
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2019097118. doi: 10.1073/pnas.2019097118
PMID: 33397815
The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent.
Skopelja-Gardner S, An J, Tai J, Tanaka L, Sun X, Hermanson P, Baum R, Kawasumi M, Green R, Gale M Jr, Kalus A, Werth VP, Elkon KB
Sci Rep. 2020 May 13;10(1):7908. doi: 10.1038/s41598-020-64865-w. Epub 2020 May 13.
PMID: 32404939
Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury.
Skopelja-Gardner S, Colonna L, Hermanson P, Sun X, Tanaka L, Tai J, Nguyen Y, Snyder JM, Alpers CE, Hudkins KL, Salant DJ, Peng Y, Elkon KB
J Immunol. 2020 May 15;204(10):2627-2640. doi: 10.4049/jimmunol.1901473. Epub 2020 Apr 1.
PMID: 32238460
Low-Avidity Autoantibodies against Bactericidal/Permeability-Increasing Protein Occur in Gram-Negative and Gram-Positive Bacteremia.
Theprungsirikul J, Thaden JT, Wierzbicki RM, Burns AS, Skopelja-Gardner S, Fowler VG Jr, Winthrop KL, Martin IW, Rigby WFC
Infect Immun. 2020 Sep 18;88(10) pii: e00444-20. doi: 10.1128/IAI.00444-20. Epub 2020 Sep 18.
PMID: 32747603
Regulation of Pseudomonas aeruginosa-Mediated Neutrophil Extracellular Traps.
Skopelja-Gardner S, Theprungsirikul J, Lewis KA, Hammond JH, Carlson KM, Hazlett HF, Nymon A, Nguyen D, Berwin BL, Hogan DA, Rigby WFC
Front Immunol. 2019;10:1670. doi: 10.3389/fimmu.2019.01670. Epub 2019 Jul 18.
PMID: 31379861
Dissociation of systemic and mucosal autoimmunity in cystic fibrosis.
Theprungsirikul J, Skopelja-Gardner S, Meagher RE, Clancy JP, Zemanick ET, Ashare A, Rigby WFC
J Cyst Fibros. 2020 Mar;19(2):196-202. doi: 10.1016/j.jcf.2019.06.006. Epub 2019 Jun 28.
PMID: 31262645
Autoimmunity to bactericidal/permeability-increasing protein in bronchiectasis exhibits a requirement for Pseudomonas aeruginosa IgG response.
Skopelja-Gardner S, Theprungsirikul J, Meagher RE, Beliveau CM, Bradley KE, Avery M, Henkle E, Siegel S, Gifford AH, Winthrop KL, Rigby WFC
Eur Respir J. 2019 Feb;53(2) pii: 1801891. doi: 10.1183/13993003.01891-2018. Epub 2019 Feb 7.
PMID: 30385530
"NETtling" the host: Breaking of tolerance in chronic inflammation and chronic infection.
Skopelja-Gardner S, Jones JD, Rigby WFC
J Autoimmun. 2018 Mar;88:1-10. doi: 10.1016/j.jaut.2017.10.008.
PMID: 29100671
Editorial: Anti-Citrullinated Protein Antibody, Anti-Carbamylated Protein Antibody, and Rheumatoid Arthritis: Azurophilic Granules Sing the Blues.
Rigby WFC, Skopelja-Gardner S, Jones JD
Arthritis Rheumatol. 2017 Dec;69(12):2251-2255. doi: 10.1002/art.40238.
PMID: 28853239
Role for ZAP-70 Signaling in the Differential Effector Functions of Rituximab and Obinutuzumab (GA101) in Chronic Lymphocytic Leukemia B Cells.
Skopelja-Gardner S, Jones JD, Hamilton BJ, Danilov AV, Rigby WFC
J Immunol. 2017 Aug 15;199(4):1275-1282. doi: 10.4049/jimmunol.1602105. Epub 2017 Jul 14.
PMID: 28710251
Mitogen-activated protein kinase phosphatase-3 (MKP-3) in the surgical wound is necessary for the resolution of postoperative pain in mice.
Skopelja-Gardner S, Saha M, Alvarado-Vazquez PA, Liponis BS, Martinez E, Romero-Sandoval EA
J Pain Res. 2017;10:763-774. doi: 10.2147/JPR.S129826. Epub 2017 Mar 28.
PMID: 28405172
HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis.
Smits NC, Kobayashi T, Srivastava PK, Skopelja S, Ivy JA, Elwood DJ, Stan RV, Tsongalis GJ, Sellke FW, Gross PL, Cole MD, DeVries JT, Kaplan AV, Robb JF, Williams SM, Shworak NW
Matrix Biol. 2017 Nov;63:69-90. doi: 10.1016/j.matbio.2017.01.003. Epub 2017 Jan 23.
PMID: 28126521
The role for neutrophil extracellular traps in cystic fibrosis autoimmunity.
Skopelja S, Hamilton BJ, Jones JD, Yang ML, Mamula M, Ashare A, Gifford AH, Rigby WF
JCI Insight. 2016 Oct 20;1(17):e88912. doi: 10.1172/jci.insight.88912. Epub 2016 Oct 20.
PMID: 27777975
Induction of interleukin-6 production by rituximab in human B cells.
Jones JD, Hamilton BJ, Skopelja S, Rigby WF
Arthritis Rheumatol. 2014 Nov;66(11):2938-46. doi: 10.1002/art.38798.
PMID: 25080282
Spinal mitogen-activated protein kinase phosphatase-3 (MKP-3) is necessary for the normal resolution of mechanical allodynia in a mouse model of acute postoperative pain.
Saha M, Skopelja S, Martinez E, Alvarez DL, Liponis BS, Romero-Sandoval EA
J Neurosci. 2013 Oct 23;33(43):17182-7. doi: 10.1523/JNEUROSCI.5605-12.2013.
PMID: 24155322