patricia.a.pioli@dartmouth.edu
Office number: 603-650-2584
Lab number: 603-650-8479
Borwell 644E
Pioli Laboratory
Featured
Research
Our research is focused on identifying the molecular mechanisms that regulate macrophage activation in autoimmunity and cancer, and how macrophage activation can be redirected for therapeutic benefit. We study the role that macrophages play in the induction and progression of the autoimmune disease systemic sclerosis (SSc) and cancer using both primary human cells and mouse models of SSc and breast cancer.
Publications
CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma.
Torres GM, Jarnagin HC, Park C, Yang H, Kosarek NN, Bhandari R, Wang CY, Kolling FW, Whitfield ML, Turk MJ, Liby KT, Pioli PA
bioRxiv. 2023 Aug 3; pii: 2023.08.01.551524. doi: 10.1101/2023.08.01.551524. Epub 2023 Aug 3.
PMID: 37577680