patricia.a.pioli@dartmouth.edu
Office number: 603-650-2584
Lab number: 603-650-8479
Borwell 644E
Pioli Laboratory
Featured
Research
Our research is focused on identifying the molecular mechanisms that regulate macrophage activation in autoimmunity and cancer, and how macrophage activation can be redirected for therapeutic benefit. We study the role that macrophages play in the induction and progression of the autoimmune disease systemic sclerosis (SSc) and cancer using both primary human cells and mouse models of SSc and breast cancer.
Publications
Single-cell epigenomic dysregulation of Systemic Sclerosis fibroblasts via CREB1/EGR1 axis in self-assembled human skin equivalents.
Abel TR, Kosarek NN, Parvizi R, Jarnagin H, Torres GM, Bhandari R, Huang M, Toledo DM, Smith A, Popovich D, Mariani MP, Yang H, Wood T, Garlick J, Pioli PA, Whitfield ML
bioRxiv. 2024 Mar 27; pii: 2024.03.22.586316. doi: 10.1101/2024.03.22.586316. Epub 2024 Mar 27.
PMID: 38585776