FEATURED ORIGINAL RESEARCH
Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity. Longmire, P., S. Zeltzer, K. Zarrella, O. Daigle, M. Svoboda, J.M. Reitsma, S.S. Terhune, C. Bobak, G. Bosco, and F. Goodrum. 2026. Nucleic Acids Research, 54(2):gkaf1445. PMID:41533576
Viral and host network analysis of the human cytomegalovirus transcriptome in latency. Collins-McMillen, D., D. De Oliviera-Pessoa, K. Zarrella, N.J. Moorman, J. P. Kamil, P. Caposio, M. Padi, and F.D. Goodrum. 2025. Proc. Natl. Acad. Sci. USA,122(22): e2416114122. PMID:40434638
Human Cytomegalovirus UL138 Interaction with USP1 Activates STAT1 in Infection. Zarrella, K., P. Longmire, S. Zeltzer, D. Collins-McMillen, M. Hancock, J. Buehler, J. Reitsma, J. Nelson, S. S. Terhune, and F. Goodrum. 2023. PLoS Pathogens, June 8; 19(6):e1011185. PMID:37289831
Host translesion polymerases are required for viral genome integrity. Zeltzer, S., P. Longmire, M. Svoboda, G. Bosco, and F. Goodrum. 2022. Proc Natl Acad Sci USA, 119(33):e2203203119. PMID: 35947614
Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency. Buehler, J., E. Carpenter, S. Zeltzer, S. Igarashi, M. Rak, I. Mikell, J.A. Nelson, and F. Goodrum. 2019. PLoS Pathogens, 15(11):e1008037. PMID: 31725811
Alternative Promoters Drive Human Cytomegalovirus Reactivation from Latency. Collins-McMillen, D., M. Rak, J.C. Buehler, S. Igarashi-Hayes, J.P. Kamil, N.J. Moorman, and F. Goodrum. 2019. Proc Natl Acad Sci USA, 116(35):17492-17497. PMID: 31409717.
Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins to Regulate Epidermal Growth Factor Receptor and Reactivation from Latency. Rak, M., J. Buehler, S. Zeltzer, J. Reitsma, S. Terhune, F. Goodrum. 2018. J Virology, 92(20): e00919-18. PMID: 30089695
Virus control of trafficking from sorting endosomes. Zeltzer, S., C. A. Zeltzer, J. Wilson, J. G. Donaldson, and F. Goodrum. 2018. MBio, 9(4): e00683-18. PMID: 30042195
FEATURED REVIEWS
DNA Damage Responses in Human Cytomegalovirus Infection: Emerging Mechanisms and Outstanding Questions. Savanagouder, M., P. Longmire, A. Hassan, D. R. McKinzey, R. Dansereau, G. Bosco, and F. Goodrum. 2026. J Virology, Jun 16:e0037626. PMID: 42300770
Human cytomegalovirus latency – the sum of subtleties. Hancock, M.H., P. Caposio, D. Collins-McMillen, N.L Diggins, B-.J. Lee, S. Medica, D. N. Streblow, T. White, A.D. Yurochko, F. Goodrum. 2025. J Virology, Jul30:e0066425. PMID:40736257
Virology – the next fifty years. Holmes, E., F. Krammer, and F. Goodrum. 2024. Cell, Sep 19; 187 (19): 5128-5145. PMID:39303682 PMC11467463
The complex biology of human cytomegalovirus latency and reactivation. Goodrum, F. 2022. In Adv.Virus Res. v112. Aug 1. PMID:35840181
FEATURED SCIENCE ADVOCACY
Bieniasz, P., C. Rice, T. Dermody, L. Enquist, F. Goodrum, D. Kushner, H. Lazear, S. Lemon, A. Pekosz, J. Purdy, V. Racaniello, T. Schountz, S. Weiss, C. Wobus, J. Alwine, S. Bertuzzi, J. Marrazzo, Shan-Lu-Liu. 2026. Protecting strength and integrity in virology. J Virology, in press. Published also as a response to Science article.
A call for the United States to continue investing in science. Blader, I. †, F. Goodrum†, M.J. Imperiale†, A. Casadevall, C. Arias, A. Baumler, C.A. Burnham, C. Cuomo, C. Detweiler, G. Forrest, J. Gilbert, S. Lovett, S. Maloy, A. McAdam, I. Newton, G. Reguera, G. O’Toole, P. D. Scloss, A. Shade, M. Whiteley. 2025. mBio, Apr 9; 16(4)e0064825. Co-published in J Virology, J Bacteriology, mSphere, mSystems, Appl. Env. Micro., ASM Case Reports, Antimicrobial Agents and Chemotherapy, J Clin.Microbiol., Microbiol Spectrum, Clin. Microbiol. Rev., Infection and Immunity, Microbiol. Resouce Announcements, Microbiol. and Mol. Bio. Rev., J Microbiol. and Bio. Educ. PMID: 40013856
The harms of promoting the lab leak hypothesis without evidence. Alwine, J.†, Goodrum†, B. Banfield, D. Bloom, W. J. Britt, A. J. Broadbent, S. K. Campos, A. Casadevall, T. Dermody, W. P. Duprex, L. W. Enquist, K. Frueh, M. Gaglia, A.P. Geballe, et al (41 authors total). 2024. J Virology, 98(9) Sep 17:e0124024. PMID: 39087765. Notable press: LA Times, TWiV, STAT
Virology – the path forward. Rasmussen, A. †, G. Gronvall†, A. Lowen†, Goodrum†, et al. (79 total authors). 2024. J Virology, 98(1)Jan 3: e0179123. PMID: 38168672
Field research is essential to counter virological threats. Runstadler, J. A., A. C. Lowen, G. Kayeli, S. M. Tompkins, R. A. Albrecht, R. A. M. Fouchier, D. E. Stallknecht, S. S. Lakdawala, F. D. Goodrum, A. Casadevall, L. W. Enquist, J. C. Alwine, M. J. Imperiale, S. Schultz-Cherry, R. J. Webby 2023. J. Virology. doi:10.1128/jvi.00544-23:e0054423. PMID:37166327
A critical analysis of the evidence for the SARS-CoV-2 origin hypotheses. Alwine, J.C., A. Casadevall, L.W. Enquist, D. Goodrum†, M.J. Imperiale. 2023. Co-published in: mBio, J Virology, mSphere. March 28. PMID: 36897089
Oversight of pathogen research must be carefully calibrated and clearly defined. Lowen, A., A. Casadevall, J.C. Alwine, L.W. Enquist, F.D. Goodrum, M.J. Imperiale, S.S. Lakdawala. 2023. Co-published in: mBio, J Virology, and mSphere. Feb 22. PMID:36811609.
Virology under the microscope – a call for rational discourse. Goodrum, F. †, A. Lowen, S. Lakdawala, J. Alwine, A. Casadevall, M. Imperiale, et al. (156 total authors). 2023. Co-published in: mBio, J Virology, and 27 Jan. . PMID: 36700640 Notable press: New York Times, NPR, Arizona Republic, and This Week in Virology (TWiV)
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