Goodrum Lab – Geisel School of Medicine at Dartmouth

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Goodrum Laboratory

Est. 2006

Est.@Dartmouth July 2025
The intersection of virology and cell biology is our sweet spot

A place for imagination to run wild!
Human Cytomegalovirus

We study virus-host interactions important in making herpesviruses forever.
DNA viruses as teachers

We study how the virus usurps and coopts DNA damage and repair, innate signaling, and differentiation pathways to sense and respond to host cues for latency/reactivation decisions

Publications

Protecting strength and integrity in virology.
Bieniasz PD, Rice CM, Dermody TS, Enquist LW, Goodrum F, Kushner DB, Lazear HM, Lemon SM, Pekosz A, Purdy J, Racaniello VR, Saif LJ, Schountz T, Weiss SR, Wobus CE, Alwine J, Bertuzzi S, Marrazzo J, Liu S-L
J Virol. 2026 Aug 26;:e0089026. doi: 10.1128/jvi.00890-26. Epub 2026 Aug 26.
PMID: 42644727

Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance.
Longmire P, Chen H, McKinzey DR, Savanagouder M, Kosarek NN, Pesola JM, Bobak CA, Bosco G, Goodrum F, Coen DM
Proc Natl Acad Sci U S A. 2026 Aug 25;123(34):e2618057123. doi: 10.1073/pnas.2618057123. Epub 2026 Aug 17.
PMID: 42607204

DNA damage responses in HCMV infection: emerging mechanisms and outstanding questions.
Savanagouder M, Longmire P, Hassan A, McKinzey D, Dansereau R, Bosco G, Goodrum F
J Virol. 2026 Jul 21;100(7):e0037626. doi: 10.1128/jvi.00376-26. Epub 2026 Jun 16.
PMID: 42300770

More Publications

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Goodrum Lab – Geisel School of Medicine at Dartmouth

Featured

Goodrum Laboratory

The intersection of virology and cell biology is our sweet spot

Human Cytomegalovirus

DNA viruses as teachers

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TWiV 973: Crouching virus, Hidden Triggers

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