Goodrum Lab – Geisel School of Medicine at Dartmouth

Our laboratory is broadly interested in complex interactions between DNA viruses and their host cells that allow viruses to subvert or co-opt cellular processes for viral objectives.

Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity. Longmire, P., S. Zeltzer, K. Zarrella, O. Daigle, M. Svoboda, J.M. Reitsma, S.S. Terhune, C. Bobak, G. Bosco, and F. Goodrum. 2026. Nucleic Acids Research, 54(2):gkaf1445. PMID:41533576

Viral and host network analysis of the human cytomegalovirus transcriptome in latency. Collins-McMillen, D., D. De Oliviera-Pessoa, K. Zarrella, N.J. Moorman, J. P. Kamil, P. Caposio, M. Padi, and F.D. Goodrum. 2025.  Proc. Natl. Acad. Sci. USA,122(22): e2416114122. PMID:40434638

Human Cytomegalovirus UL138 Interaction with USP1 Activates STAT1 in Infection. Zarrella, K., P. Longmire, S. Zeltzer, D. Collins-McMillen, M. Hancock, J. Buehler, J. Reitsma, J. Nelson, S. S. Terhune, and F. Goodrum. 2023. PLoS Pathogens, June 8; 19(6):e1011185. PMID:37289831