Department of Microbiology and Immunology
Geisel School of Medicine at Dartmouth
One Medical Center Blvd.
Borwell 603E
Lebanon, NH 03756
felicia.goodrum@dartmouth.edu
ph. (603) 646-5779
Goodrum Lab – Geisel School of Medicine at Dartmouth
Featured
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Goodrum Laboratory

Est. 2006
Est.@Dartmouth July 2025
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The intersection of virology and cell biology is our sweet spot
A place for imagination to run wild!

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Human Cytomegalovirus
We study virus-host interactions important in making herpesviruses forever.

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DNA viruses as teachers
We study how the virus usurps and coopts DNA damage and repair, innate signaling, and differentiation pathways to sense and respond to host cues for latency/reactivation decisions

About
Our laboratory is broadly interested in complex interactions between DNA viruses and their host cells that allow viruses to subvert or co-opt cellular processes for viral objectives.
TWiV 973: Crouching virus, Hidden Triggers
Publications
DNA damage responses in HCMV infection: emerging mechanisms and outstanding questions.
Savanagouder M, Longmire P, Hassan A, McKinzey D, Dansereau R, Bosco G, Goodrum F
J Virol. 2026 Jun 16;:e0037626. doi: 10.1128/jvi.00376-26. Epub 2026 Jun 16.
PMID: 42300770
Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance.
Longmire P, Chen H, McKinzey DR, Savanagouder M, Kosarek NN, Pesola JM, Bobak CA, Bosco G, Goodrum F, Coen DM
bioRxiv. 2026 May 22; pii: 2026.05.21.726832. doi: 10.64898/2026.05.21.726832. Epub 2026 May 22.
PMID: 42239149
Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity.
Longmire P, Zeltzer S, Zarrella K, Daigle O, Svoboda M, Reitsma JM, Terhune SS, Bobak C, Bosco G, Goodrum F
Nucleic Acids Res. 2026 Jan 14;54(2) doi: 10.1093/nar/gkaf1445.
PMID: 41533576
More Publications
