Current and Past Lab Members

Current lab member profiles

Alicia Bostwick-Galaviz: Graduate Student (Cell Type: Al-B-cia)

What is one sentence that describes your work?: I'm using a flow cytometry-based metabolic assay to uncover the differences in mitochondrial NAD redox state between phenotypic subsets of T cells.

If you could be any immune cell what would you be?: I would be an activated B cell because I like sharing with others, I like finding optimal solutions to a problem, and sometimes I get a liiiitle too obsessed with the small details.

What is your favorite metabolite/metabolic enzyme?: NAD+/NADH

What made you want to go into immunology?: I think that how interconnected everything is in immunology is super cool. I wanted to do science research that could help fight disease in people and benefit the health of others.

What do you like do to outside of lab?: Running!! 🙂 

 

Alex Turnquist: Graduate Student (Cell Type: Neutroph-Al) 

What is one sentence that describes your work?: I study how  to alter metabolic programming in T cells to better promote tumor killing and maintenance of anti-tumor responses. 

If you could be any immune cell what would you be?: I would be a neutrophil because I work in chaotic spurts and sometimes have a hard time regulating how excited I get about things. I've yet to puke out my guts, but there's a lot of time left in grad school for that to happen. 

What is your favorite metabolite/metabolic enzyme?: Biiiiig ADH fan 

What made you want to go into immunology?: I became interested in immunology because I loved how complicated it was and how many questions there were left to answer. I wanted to do something that could help people, and I also thought that I would sound really smart if I told people I was an immunologist. 

What do you like do to outside of lab?: I like to cuddle with my cats, take care of my many plants, do music-y things (you're looking at the 2022 M&I karaoke champion here), go to the Norwich farmers market, and hike around the Upper Valley.  

 

Danielle Douglas: Graduate Student (Cell Type: NK cell)

What is one sentence that describes your work?: I study how we can promote a stem-like phenotype in T cells before adoptive transfer to improve therapeutic outcomes against melanoma.

If you could be any immune cell, what would you be?: If I could be any immune cell, I’d be an NK cell. They trust their instincts, just like I do when exploring new ideas in the lab. But they’re also careful and thorough, striking the perfect balance between creativity and precision, which are qualities I aim to embody in my research.

What is your favorite metabolite/metabolic enzyme?: Citrate, hands down. It’s the overachiever of the TCA cycle and deserves more credit for keeping things running smoothly. Why bother turning into acetyl-CoA and getting tangled up in fatty acid synthesis? T cells fighting cancer need energy, not lipid droplets slowing them down!

What made you want to go into immunology?: I love how complex and dynamic the immune system is. Immune cells work together like an orchestra, crafting a melody that masterfully adapts to defeat each unique enemy. As an immunologist, I believe it’s essential to look beyond a single instrument and focus on the interplay between them, as the harmony creates the symphony of immune defense.

What do you like to do outside of lab?: I enjoy getting creative in my downtime, whether it’s making candles, painting, or trying needlepoint. I also love playing Dungeons and Dragons with friends in my cohort; it’s a fun way to unwind and connect. When I’m not crafting or rolling dice, I’m watching Survivor with my roommate or exploring Boston to visit family, friends, and my boyfriend. If you need North End restaurant tips, I’ve got you covered!

 

Emily-Claire Duffy: Graduate Student (Cell Type: Emil-T Reg)

What is one sentence that describes your work?: I am investigating how increased fatty acid oxidation in CD8+ T cells drives their survival and function as an ovarian cancer therapeutic.

If you could be any immune cell what would you be?: I would be a regulatory T cell because I like to help put out fires and calm people down when things get too hectic. I am very trusting and eager to help others, but sometimes have trouble knowing when to leave things alone.

What is your favorite metabolite/metabolic enzyme?: Carnitine

What made you want to go into immunology?: I love the idea of utilizing our body's own defense system to enhance cancer therapeutics. Our immune system is so fine tuned and interconnected, so the opportunities seem limitless!

What do you like do to outside of lab?: I like to hike, spend time in the ocean, and hang with my dog Gus.

 

Taewook Kang: Postdoctoral Researcher (Cell Type: Memory T-wook)

What is one sentence that describes your work?:I look at improving CD8 T cell immunotherapy by genetic manipulation of pyruvate metabolism. 

If you could be any immune cell what would you be?: I would be a memory T cell: My lifestyle and work style is slow and steady. I am a minimalist and want to live healthy and a long life.

What is your favorite metabolite/metabolic enzyme?:Pyruvate

What made you want to go into immunology?: I thought that immunology looks like a world in a game where players all evolve over time. 

What do you like do to outside of lab?: I like to cook and swim. I ski in the winter as well. 

 

Young Usherwood, PhD: Lab Manager (Cell Type: Dendri-Young Cell)

What is one sentence that describes your work?:   I manage the lab expenses and ordering and I am the lab's molecular biology core.

If you could be any immune cell what would you be?:  A dendritic cell, so my processes can keep in touch with everything going on in the lab.

What is your favorite metabolite/metabolic enzyme?:   Glucose - my cakes would not be tasty without it!

What made you want to go into about immunology?:  I am fascinated by how different parts of the immune system work together during disease, and learning about ways we can manipulate different processes to improve immunity to cancer and infectious disease.

 What do you like do to outside of lab?:  I like to paint, cook and tend my flower garden in the spring and summer.

 

Ed Usherwood, PhD: PI (Cell Type: Basoph-Ed)

What is one sentence that describes your work?:  We strive to improve the quality T cells used for immunotherapy, which will improve their effectiveness regardless of targeting strategy.

If you could be any immune cell what would you be?: The basophil because they are rare and mysterious……..

What is your favorite metabolite/metabolic enzyme?:  Acetyl-CoA because it is versatile and always at the center of things.

What made you want to go into you about immunology?: As a young child a radioactive T cell degranulated on me. Ever since then I see these immune networks in my head.

 What do you like do to outside of lab?: Baking bread, hiking and being a perpetually disappointed England soccer fan.

 

Lab Alumni/-ae

Joshua Obar - Associate Professor, Geisel School of Medicine at Dartmouth.

Shinchiro Fuse - Partner/Managing Director TPG Life Sciences Innovation.

Mike Molloy - Director, ImmuNext.

Rameeza Allie - Assistant Professor, University of Pennsylvania, Hershey.

Zhuting Hu - Scientist, ElevateBio.

Rebecca Crepeau - Medical Publications Manager, Aptitude Health.

Ji-Young Hwang - Scientist II, Repertoire Immune Medicines.

Yanbo Sun - Postdoctoral Fellow, Dana-Farber Cancer Institute.

Ji-Young Hwang - Senior Researcher, Korea Research Institute of Bioscience and Biotechnology.

Kristine Valenteros - Scientist CMC, Takeda Pharmaceuticals.

Christopher Carroll - Graduate student, Florida State University

Nicholas Preiss - Orange Grove Bio