Recent publications

Guidelines for T cell nomenclature.
Masopust D, Awasthi A, Bosselut R, Brooks DG, Buggert M, Chamoto K, Cui W, Dong C, Farber DL, Gebhardt T, Gerlach C, Goldrath A, Greenberg PD, Hale JS, Hayday A, Homann D, Iannacone M, Jameson SC, Jenkins MK, Joshi NS, Kaech SM, Kallies A, Kamphorst AO, Kaplan MH, Klenerman P, Kunzli M, Lanzavecchia A, Lauer GM, Lugli E, Luster AD, Mackay LK, McElrath MJ, Mueller SN, Ndhlovu Z, Ndung'u T, Ohashi PS, Oxenius A, Pantaleo G, Pepper M, Picker LJ, Quarnstrom CF, Reyes-Teran G, Roederer M, Rosato PC, de Oca GS, Sallusto F, Schumacher TN, Schwartz DM, Shin EC, Soerens AG, Thommen DS, Vezys V, Viola JPB, Walker BD, Watts TH, Weaver CT, Wherry EJ, Xue HH, Youngblood B, Ahmed R
Nat Rev Immunol. 2025 Nov 18; doi: 10.1038/s41577-025-01238-2. Epub 2025 Nov 18.
PMID: 41254224

Primate resident memory T cells activate humoral and stromal immunity.
Joag V, Bimber BN, Quarnstrom CF, Bollimpelli VS, Schenkel JM, Fraser KA, Bertogliat M, Soerens AG, Stolley JM, O'Flanagan SD, Rosato PC, Gavil NV, Kunzli M, Mitchell JS, Legere T, Jean S, Upadhyay AA, Kang CY, Gibbs J, Yewdell JW, Fife BT, Park H, Hansen SG, Bosinger SE, Barber GN, Skinner PJ, Vezys V, Hunter E, Picker LJ, Amara RR, Masopust D
Immunity. 2025 Oct 14;58(10):2541-2555.e6. doi: 10.1016/j.immuni.2025.09.009.
PMID: 41092897

Women in STEM becoming independent: People should feel free to be themselves and do great science.
Liu S, Saraiva M, Bartman CR, Saurat N, Rosato PC, Licona-Limon P, Mendoza A, Guthmiller J, Mlynarczyk C, Goldberg E
J Exp Med. 2025 Sep 1;222(9) pii: e20251386. doi: 10.1084/jem.20251386. Epub 2025 Aug 8.
PMID: 40778912

Targeting pyruvate metabolism generates distinct CD8+ T cell responses to gammaherpesvirus and B lymphoma.
Kang T, Usherwood YK, Reisz JA, Kamerkar SC, Culp-Hill R, Wilkins OM, Verissimo AF, Kolling FW 4th, Hung AM, Musial SC, Rosato PC, D'Alessandro A, Higgs HN, Usherwood EJ
JCI Insight. 2025 Aug 22;10(16) doi: 10.1172/jci.insight.187680. Epub 2025 Aug 22.
PMID: 40857407

Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids generates antitumor responses that eliminate tumoral T regs.
Ho GW, Santos A, Fields J, Rosato PC, Turk MJ, Steinmetz NF, Fiering S
Sci Rep. 2025 Jul 8;15(1):24439. doi: 10.1038/s41598-025-09535-5. Epub 2025 Jul 8.
PMID: 40628928

Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids generates antitumor responses that eliminate tumoral T regs.
Ho GW, Santos A, Fields J, Rosato PC, Turk MJ, Steinmetz NF, Fiering S
bioRxiv. 2025 May 25; pii: 2025.05.20.655082. doi: 10.1101/2025.05.20.655082. Epub 2025 May 25.
PMID: 40661414

The endogenous antigen-specific CD8(+) T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments.
Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Musial SC, Kolling FW, Obar JJ, Rosato PC, Ackerman ME, Song L, McKenna A, Huang YH
Immunity. 2025 Mar 11;58(3):601-615.e9. doi: 10.1016/j.immuni.2025.02.001. Epub 2025 Feb 27.
PMID: 40020673

Alarm Functions of PD-1+ Brain-Resident Memory T Cells.
Musial SC, Kleist SA, Degefu HN, Ford MA, Chen T, Isaacs JF, Boussiotis VA, Skorput AGJ, Rosato PC
J Immunol. 2024 Dec 1;213(11):1585-1594. doi: 10.4049/jimmunol.2400295.
PMID: 39413000

Nasal and Pharyngeal Mucosal Immunity to Poliovirus in Children Following Routine Immunization With Inactivated Polio Vaccine in the United States.
Godin A, Connor RI, Degefu HN, Rosato PC, Wieland-Alter WF, Axelrod KS, Kovacikova G, Weiner JA, Ackerman ME, Chen EY, Arita M, Bandyopadhyay AS, Raja AI, Modlin JF, Brickley EB, Wright PF
J Infect Dis. 2024 Nov 15;230(5):e1023-e1030. doi: 10.1093/infdis/jiae264.
PMID: 38809190

Depletion of conventional CD4(+) T cells is required for robust priming and dissemination of tumor antigen-specific CD8(+) T cells in the setting of anti-CD4 therapy.
Ramirez DE, Dragnev CPC, Searles TG, Spicer N, Chen T, Lines JL, Hawkes AR, Davis WL, Mohamed A, Shirai K, Phillips JD, Rosato PC, Huang YH, Turk MJ
J Immunother Cancer. 2024 Nov 9;12(11) doi: 10.1136/jitc-2024-010170. Epub 2024 Nov 9.
PMID: 39521617