We are located on the 7th floor of the Rubin Building in Dartmouth-Hitchcock Medical Center
Office: Rubin 732
603.653.6125 (office)
Rosato Laboratory
Featured
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GBMtetramer
Research
Tissue resident memory T cells (TRM) combine the exquisite specificity of adaptive immunity, with rapid frontline antiviral functions conventionally executed by innate immune cells.
Our lab is interested in understanding the function and regulation of TRM in distinct tissue environments to be able to contextualize their role in cancer, infection and autoimmunity.
Our current focuses:
• TRM in the brain
• TRM as a brain tumor immunotherapy
• TRM and oncolytic viral therapy
Recent Publications
Guidelines for T cell nomenclature.
Masopust D, Awasthi A, Bosselut R, Brooks DG, Buggert M, Chamoto K, Cui W, Dong C, Farber DL, Gebhardt T, Gerlach C, Goldrath A, Greenberg PD, Hale JS, Hayday A, Homann D, Iannacone M, Jameson SC, Jenkins MK, Joshi NS, Kaech SM, Kallies A, Kamphorst AO, Kaplan MH, Klenerman P, Kunzli M, Lanzavecchia A, Lauer GM, Lugli E, Luster AD, Mackay LK, McElrath MJ, Mueller SN, Ndhlovu Z, Ndung'u T, Ohashi PS, Oxenius A, Pantaleo G, Pepper M, Picker LJ, Quarnstrom CF, Reyes-Teran G, Roederer M, Rosato PC, de Oca GS, Sallusto F, Schumacher TN, Schwartz DM, Shin EC, Soerens AG, Thommen DS, Vezys V, Viola JPB, Walker BD, Watts TH, Weaver CT, Wherry EJ, Xue HH, Youngblood B, Ahmed R
Nat Rev Immunol. 2025 Nov 18; doi: 10.1038/s41577-025-01238-2. Epub 2025 Nov 18.
PMID: 41254224
Primate resident memory T cells activate humoral and stromal immunity.
Joag V, Bimber BN, Quarnstrom CF, Bollimpelli VS, Schenkel JM, Fraser KA, Bertogliat M, Soerens AG, Stolley JM, O'Flanagan SD, Rosato PC, Gavil NV, Kunzli M, Mitchell JS, Legere T, Jean S, Upadhyay AA, Kang CY, Gibbs J, Yewdell JW, Fife BT, Park H, Hansen SG, Bosinger SE, Barber GN, Skinner PJ, Vezys V, Hunter E, Picker LJ, Amara RR, Masopust D
Immunity. 2025 Oct 14;58(10):2541-2555.e6. doi: 10.1016/j.immuni.2025.09.009.
PMID: 41092897
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