Tissue resident memory T cells (TRM) combine the exquisite specificity of adaptive immunity, with rapid frontline antiviral functions conventionally executed by innate immune cells.
Our lab is interested in understanding the function and regulation of TRM in distinct tissue environments to be able to contextualize their role in cancer, infection and autoimmunity.
Our current focuses:
• TRM in the brain
• TRM as a brain tumor immunotherapy
• TRM and oncolytic viral therapy
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