Jomkuan (Lynn) Theprungsirikul, PhD
I graduated from Duke University in 2014 with a BS in Biology. From sophomore to senior year of my undergraduate studies, I worked in the Cellular Biology lab of Dr. Zhen-Ming Pei to investigate the hyperosmolality-gated calcium-permeable channel and its function in osmosensing in Arabidopsis. Shortly after graduation, I began to work in Dr. Shyni Varghese's Bio-Inspired Materials and Stem Cell Engineering lab at UC San Diego. During my time there, I and a group of graduate students developed 3D cardiac microtissues within a microfluidic device with the ability to quantify real-time contractile stress measurements for use in drug discovery and development. We also developed a cancer-on-a-chip platform that recapitulates the blood vessel-cancer tissue interface through co-culturing of endothelial and cancer cells for use as an oncologic drug-screening platform or in vitro systems for immunooncology. In 2016, I joined the Molecular and Cellular Biology Program at Dartmouth. I joined Dr. William Rigby's lab in 2017 to pursue my PhD. My research focus in Dr. Rigby's lab is on autoimmunity in cystic fibrosis patients during Pseudomonas aeruginosa infection.
Selected Publications
Differential Enhancement of Neutrophil Phagocytosis by Anti–Bactericidal/Permeability-Increasing Protein Antibodies
Theprungsirikul J, Skopelja-Gardner S, Wierzbicki RM, Sessions KJ, Rigby WFC. Differential Enhancement of Neutrophil Phagocytosis by Anti–Bactericidal/Permeability-Increasing Protein Antibodies. J Immunol. 2021. DOI: 10.4049/jimmunol.2100378
Killing three birds with one BPI: Bactericidal, opsonic, and anti-inflammatory functions.
Theprungsirikul J, Skopelja-Gardner S, Rigby WFC. Journal of Translational Autoimmunity. 2021. DOI: 10.1016/j.jtauto.2021.100105