News and Events
July 16, 2021
Lab published articles: Theprungsirikul J, Skopelja-Gardner S, Wierzbicki RM, Sessions KJ, Rigby WFC. Differential Enhancement of Neutrophil Phagocytosis by Anti–Bactericidal/Permeability-Increasing Protein Antibodies. J Immunol. 2021. DOI: 10.4049/jimmunol.2100378
May 28, 2021
Lab published articles: Theprungsirikul J, Skopelja-Gardner S, Rigby WFC. Killing three birds with one BPI: Bactericidal, opsonic, and anti-inflammatory functions. Journal of Translational Autoimmunity. 2021. DOI: 10.1016/j.jtauto.2021.100105
April 28, 2021
Lynn Theprungsirikul successfully defends her thesis and receives PhD degree in Immunology
April 7, 2021
Lab published articles: Theprungsirikul J, Skopelja-Gardner S, Burns AS, Wierzbicki RM, Rigby WFC. Bactericidal/permeability-increasing protein (BPI) preeminently mediates clearance of Pseudomonas aeruginosa in vivo via CD18-dependent phagocytosis. Front. Immunol. 2021. DOI: 10.3389/fimmu.2021.659523
January 11, 2021
Katherine Sessions joins the Rigby lab as our research associate.
November 23, 2020
Ashley Burns completes her work in the Rigby lab.
October 21-23, 2020
Lynn Theprungsirikul presents a poster at the North America Cystic Fibrosis Conference 2020 (virtual), entitled: "BPI and its importance in combating bacterial infections in murine models".
October 12, 2020
Rachel Wierzbicki completes her work in the Rigby lab.
October 5, 2020
Sladjana Skopelja-Gardner joins the Rigby lab as a collaborator on our project.
August 3, 2020
Lab published articles: J. Theprungsirikul, J. T. Thaden, R. M. Wierzbicki, A. S. Burns, S. Skopelja-Gardner, V. G. Fowler Jr., K. L. Winthrop, I. W. Martin, W. F. C. Rigby. Low-Avidity Autoantibodies Against Bactericidal/Permeability Increasing Protein Occur in Gram-Negative and Gram-Positive Bacteremia; Infection and Immunity. (2020). https://iai.asm.org/content/early/2020/07/28/IAI.00444-20
November 8-13, 2019
Dr. Rigby was named the Master of the American College of Rheumatology this year at the ACR/ARP conference in Atlanta, GA. Recognition as a Master of the American College of Rheumatology is one of the highest honors the College bestows. The designation of Master is conferred on ACR members who have made outstanding contributions to the ACR and the field of rheumatology through scholarly achievement and/or service to their patients, students, and profession.
October 30-November 2
Lynn Theprungsirikul presents a poster at the North America Cystic Fibrosis Conference 2019 in Nashville, TN, entitled: "Dissociation of systemic and mucosal autoimmunity in cystic fibrosis".
August 16, 2019
Brenda Miao completes her work in the Rigby lab.
July 18, 2019
Lab publishes article: Sladjana Skopelja-Gardner, Jomkuan Theprungsirikul, Kimberley A. Lewis, John H. Hammond, Kyrsten M. Carlson, Haley F. Hazlett, Amanda Nymon, Dao Nguyen, Brent L. Berwin, Deborah A. Hogan, and William F. C. Rigby. Regulation of Pseudomonas aeruginosa-Mediated Neutrophil Extracellular Traps; Frontiers in Immunology. (2019). https://doi.org/doi.org/10.3389/fimmu.2019.01670
June 28, 2019
Lab published articles: Theprungsirikul J, Skopelja-Gardner S, Meagher RE, Clancy, Zemanick ET, Ashare A, Rigby WFC. Dissociation of systemic and mucosal autoimmunity in cystic fibrosis; Journal of Cystic Fibrosis. (2019). https://doi.org/10.1016/j.jcf.2019.06.006
June 23-26, 2019
Lynn Theprungsirikul presents a poster at the Cystic Fibrosis Foundation Research Conference: Pushing the Frontiers 2019, in Stowe, VT, entitled: "Breaking of Tolerance to BPI in Cystic Fibrosis Patients".
March 12, 2019
Lynn Theprungsirikul presents her research in breaking of tolerance to BPI in Cystic Fibrosis at the Dartmouth Cystic Fibrosis Annual Retreat on March 12, 2019 in Hanover, NH.
November 1, 2018
The lab publishes their research letter on autoimmunity to BPI:
Skopelja-Gardner S, Theprungsirikul J, Meagher RE, et al. Autoimmunity to bactericidal/permeability-increasing protein in bronchiectasis exhibits a requirement for Pseudomonas aeruginosa IgG response. Eur Respir J 2018; in press
(https://doi.org/10.1183/13993003.01891-2018)
October 19-23, 2018
Dr. Rigby presents his research at the American College of Rheumatology/the Association of Rheumatology Health Professionals (ACR/ARHP) Conference between October 19-23, 2018 in Chicago, Illinois.
August 16, 2018
Dr. Gregg Silverman from NYU School of Medicine met with the lab to discuss current and future collaborations.
July 12-14, 2018
Lynn Theprungsirikul presents a poster at the World Bronchiectasis Conference 2018 in Washington DC, entitled: "Autoimmunity to Bactericidal/Permeability-Increasing Protein in Chronic Airway Infection of Bronchiectasis and Cystic Fibrosis Patients".
June 18, 2018
Undergraduate student, Beth Daniels, joins the lab as an intern.
May 23, 2018
Undergraduate student, Brenda Miao, presents a poster at the Wetterhahn Science Symposium 2018 at Dartmouth College, entitled: "NET Neutrality: Targets of Autoantibodies localized to Neutrophil Extracellular Traps".
March 29, 2018
Rigby lab attends the Dartmouth Cystic Fibrosis Retreat held at Hanover Inn, Hanover, NH
March 21, 2018
Undergraduate student, Meade Avery, joins the lab as an intern
November 2-4, 2017
Lynn Theprungsirikul presents a poster at the North America Cystic Fibrosis Conference 2017 in Indianapolis, IN, entitled: "LasR Regulates Pseudomonas Aeruginosa-Mediated Neutrophil Extracellular Trap Formation".
October 31, 2017
The lab publishes their review article on Neutrophil Extracellular Trap: Skopelja-Gardner S, Jones JD, Rigby WFC. “NETtling” the host: Breaking of tolerance in chronic inflammation and chronic infection; J Autoimmun. (2017) PMID: 29100671
October 14-15, 2017
Lynn Theprungsirikul presents a poster at the New England Immunology Conference in Woods Hole, MA, entitled: "LasR Regulates Pseudomonas Aeruginosa-Mediated Neutrophil Extracellular Trap Formation".
October 4, 2017
Lynn Theprungsirikul presents a poster on LasR and its regulation in NETs formation at the Dartmouth CF RDP External Advisory Committee Site Visit in Hanover, NH.
August 18, 2017
Cathleen Beliveau completes her summer internship in the lab.
July 5, 2017
Rachel Meagher joins the lab as a research associate.
June 1, 2017
Undergraduate student, Cathleen Beliveau W'18 joins the lab as a summer intern
June 1, 2017
Jomkuan (Lynn) Theprungsirikul officially joins the lab as a PhD student in the MCB program
April 25, 2017
Skopelja-Gardner successfully defends her thesis and receives PhD degree in Immunology
March 30, 2017
Dr. Rigby receives a research grant from the Cystic Fibrosis Foundation to conduct research on Autoimmunity in Cystic Fibrosis!
Skopelja-Gardner presents at the Cystic Fibrosis Conference in Hanover, NH on the topic "The Role for NETs in CF Autoimmunity".
March 15, 2017
Lab publishes their work on Anti-carbamylated protein autoantibodies in Arthritis and Rheumatology
February 6, 2017
The article on the project "Autoimmunity in Cystic Fibrosis" conducted by the lab is featured on the School of Graduate and Advanced Studies website.
January 31, 2017
Dr. Martin Kriegel from Yale School of Medicine meets with the lab to share his expertise on the role of microbiota in immunity and to discuss opportunities for future collaborations.
January 18, 2017
Sladjana Skopelja-Gardner presents a seminar at the Lung Biology Meeting at Dartmouth entitled: "Understanding autoimmunity in lung diseases in the context of Pseudomonas Aeruginosa infection"
January 2017
Dartmouth College student Brenda Miao joins to work under the mentorship of Dr. Jones on studying the role of complement in NETosis.
December 2016
Jomkuan (Lynn) Theprungsirikul, a PhD student in the program of Molecular and Cellular Biology, joins the lab for a rotation.
October 20, 2016
The lab publishes their work on Autoimmunity in Cystic Fibrosis: Skopelja, S., Hamilton, B. J., Jones, J. D., Yang ML., Mamula. M., Ashare, A., Gifford, A. H., Rigby, W. F. C. The role for neutrophil extracellular traps in cystic fibrosis autoimmunity; JCI Insight. (2016) PMID: 27777975
August 24, 2016
Kyrsten Carlson completes her summer internship in the lab.
August 12, 2016
Dr. Jones has been awarded a Pfizer Aspire grant for the project: "Complement C4 deficiency impairs clearance of rheumatoid arthritis autoantigens associated with neutrophil extracellular traps (NETs)".
August 4, 2016
Dr. Gregg Silverman from NYU Medical School met with the lab to discuss current and future collaborations.
July 23-30, 2016
Sladjana Skopelja attended Applied Bioinformatics Course at the Mount Desert Institute Biological Laboratory, in Bar Harbor, Maine.
June 28, 2016
Dr. Mark Mamula from Yale School of Medicine met with the lab to discuss current and future collaborations.
June 1, 2016
Undergraduate student Kyrsten Carlson, RPI '19 joins the lab as a summer intern.
May 15, 2016
Sladjana Skopelja presents the poster, The Nature and Role of Autoimmunity in Cystic Fibrosis, at the AAI annual meeting in Seattle, WA
April 2016
Article published in the Dartmouth Medicine Magazine featuring the research of Dr. Rigby and Dr. Amos on complement in rheumatoid arthritis: Untangling Genetic Factors in Rheumatoid Arthritis
April 4, 2016
Undergraduate student Katherine Bradley D'17 joins the lab to work with Sladjana Skopelja on the study of autoimmunity in cystic fibrosis and to conduct honors thesis research.
March 30, 2016
Undergraduate student Nicole Knape D'19 joins the lab to work with Dr. Jones.
March 22, 2016
Sladjana Skopelja gives a talk at the Dartmouth Cystic Fibrosis retreat entitled, Autoimmunity in Cystic Fibrosis.
February 15, 2016
Savannah Barnett joins the lab as a rotation student.
October 17-18, 2015
Sladjana Skopelja presented a poster at the New England Immunology Conference in Woods Hole, MA, entitled: "Nature and Development of Autoimmunity in Cystic Fibrosis".
October 7, 2015
Dr. Rigby speaks to the Immunology and Microbiology Department at Dartmouth on the topic: "Gene copy number variation and rheumatoid arthritis: complements of the genome".