Recent Publications

Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage.
MacKenzie A, Vicory V, Lacefield S
PLoS Genet. 2023 Apr;19(4):e1010707. doi: 10.1371/journal.pgen.1010707. Epub 2023 Apr 5.
PMID: 37018287

Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation.
Cairo G, Greiwe C, Jung GI, Blengini C, Schindler K, Lacefield S
Mol Biol Cell. 2023 May 1;34(5):ar43. doi: 10.1091/mbc.E23-01-0014. Epub 2023 Mar 15.
PMID: 36920098

Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation.
Cairo G, Greiwe C, Jung GI, Blengini C, Schindler K, Lacefield S
bioRxiv. 2023 Feb 5; pii: 2023.02.05.527197. doi: 10.1101/2023.02.05.527197. Epub 2023 Feb 5.
PMID: 36778459

Meiotic Cells Escape Prolonged Spindle Checkpoint Activity Through Premature Silencing and Slippage.
MacKenzie A, Vicory V, Lacefield S
bioRxiv. 2023 Jan 2; pii: 2023.01.02.522494. doi: 10.1101/2023.01.02.522494. Epub 2023 Jan 2.
PMID: 36711621

High-throughput genetic screening of meiotic commitment using fluorescence microscopy in Saccharomyces cerevisiae.
Gavade JN, Lacefield S
STAR Protoc. 2022 Dec 16;3(4):101797. doi: 10.1016/j.xpro.2022.101797. Epub 2022 Oct 27.
PMID: 36325582

Use of Time-Lapse Microscopy and Stage-Specific Nuclear Depletion of Proteins to Study Meiosis in S. Cerevisiae.
Cairo G, MacKenzie A, Tsuchiya D, Lacefield S
J Vis Exp. 2022 Oct 11;(188) doi: 10.3791/64580. Epub 2022 Oct 11.
PMID: 36314815

Identification of 14-3-3 proteins, Polo kinase, and RNA-binding protein Pes4 as key regulators of meiotic commitment in budding yeast.
Gavade JN, Puccia CM, Herod SG, Trinidad JC, Berchowitz LE, Lacefield S
Curr Biol. 2022 Apr 11;32(7):1534-1547.e9. doi: 10.1016/j.cub.2022.02.022. Epub 2022 Mar 2.
PMID: 35240051

The mitotic exit network regulates the spatiotemporal activity of Cdc42 to maintain cell size.
Gihana GM, Cross-Najafi AA, Lacefield S
J Cell Biol. 2021 Jan 4;220(1) doi: 10.1083/jcb.202001016.
PMID: 33284320

CDK Regulation of Meiosis: Lessons from S. cerevisiae and S. pombe.
MacKenzie AM, Lacefield S
Genes (Basel). 2020 Jun 29;11(7) doi: 10.3390/genes11070723. Epub 2020 Jun 29.
PMID: 32610611

Establishing correct kinetochore-microtubule attachments in mitosis and meiosis.
Cairo G, Lacefield S
Essays Biochem. 2020 Sep 4;64(2):277-287. doi: 10.1042/EBC20190072.
PMID: 32406497