May 2026
Published in npj Systems Biology and Applications and authored by research assistant Jeffrey Hage: A new statistical method for recovering count information from proportional data by applying trained priors, named Mahalanobis Count Inference (MCI). The method is generally applicable to multiple kinds of biological measurements (e.g. single-cell transcriptomics).
Inferring absolute counts from proportions by constraining multivariate normal distributions
November 2024
QBS Ph.D. student Ze Zhang, published an application of detailed DNA-based immune profiling in head and neck cancer immunotherapy response in npj Precision Oncology.
June 2024
Congratulations to graduating Dartmouth senior Samuel Reynolds who contributed two lead-author manuscripts related to his independent study and senior honors thesis work in the lab on DNA based cell typing with methylation cytometry.
Detailed immune profiling in pediatric Crohn's disease using methylation cytometry
April 2024
Ph.D. student Sarah Lee published back-to-back articles in Nature Communications on single-cell gene expression and epigenetic modifications in pediatric central nervous system tumors.
February 2022
Dr. Lucas Salas M.D., MPH, Ph.D., and QBS Ph.D. student Ze Zhang, published their novel immune-profiling method using DNA from blood in Nature Communications. Their work is picked up by the online news services GenomeWeb and Medical Xpress.