The Yersinia pestis effector YopM binds the human pyrin death domain to inhibit inflammasome activation and effector-triggered immunity.
Mwaura BW, Simard AR, Pettis ML, Liu A, Madden DR, Bliska JB
bioRxiv. 2026 Mar 25; pii: 2026.02.25.707193. doi: 10.64898/2026.02.25.707193. Epub 2026 Mar 25.
PMID: 41929001
Sex and regional effects of Bacteroides in the gut.
Valls RA, Barrack KE, Surve SV, Bliska JB, O'Toole GA
bioRxiv. 2025 Aug 27; pii: 2025.08.27.672693. doi: 10.1101/2025.08.27.672693. Epub 2025 Aug 27.
PMID: 40909589
ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils.
Reuven AD, Katzenell S, Mwaura BW, Bliska JB
PLoS Pathog. 2025 Apr;21(4):e1013021. doi: 10.1371/journal.ppat.1013021. Epub 2025 Apr 2.
PMID: 40173191
Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.
Malik HS, Bliska JB
PLoS Pathog. 2025 Jan;21(1):e1012884. doi: 10.1371/journal.ppat.1012884. Epub 2025 Jan 30.
PMID: 39883598
A type VI secretion system in Burkholderia species cenocepacia and orbicola triggers distinct macrophage death pathways independent of the pyrin inflammasome.
Loeven NA, Dabi C, Pennington JP, Reuven AD, McGee AP, Mwaura BW, Bliska JB
Infect Immun. 2024 Dec 10;92(12):e0031624. doi: 10.1128/iai.00316-24. Epub 2024 Oct 31.
PMID: 39480100
A Type VI Secretion System in Burkholderia Species cenocepacia and orbicola Triggers Distinct Macrophage Death Pathways Independent of the Pyrin Inflammasome.
Loeven NA, Reuven AD, McGee AP, Dabi C, Mwaura BW, Bliska JB
bioRxiv. 2024 May 20; pii: 2023.09.28.559184. doi: 10.1101/2023.09.28.559184. Epub 2024 May 20.
PMID: 38826213
ExoS Effector in Pseudomonas aeruginosa Hyperactive Type III Secretion System Mutant Promotes Enhanced Plasma Membrane Rupture in Neutrophils.
Reuven AD, Mwaura BW, Bliska JB
bioRxiv. 2024 Jan 25; pii: 2024.01.24.577040. doi: 10.1101/2024.01.24.577040. Epub 2024 Jan 25.
PMID: 38328038
Phosphoprotein phosphatase activity positively regulates oligomeric pyrin to trigger inflammasome assembly in phagocytes.
Malik HS, Magnotti F, Loeven NA, Delgado JM, Kettenbach AN, Henry T, Bliska JB
mBio. 2023 Oct 31;14(5):e0206623. doi: 10.1128/mbio.02066-23. Epub 2023 Oct 3.
PMID: 37787552
Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins.
Oh C, Li L, Verma A, Reuven AD, Miao EA, Bliska JB, Aachoui Y
Cell Rep. 2022 Nov 22;41(8):111688. doi: 10.1016/j.celrep.2022.111688.
PMID: 36417874
Correction: γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans.
Chu TH, Khairallah C, Shieh J, Cho R, Qiu Z, Zhang Y, Eskiocak O, Thanassi DG, Kaplan MH, Beyaz S, Yang VW, Bliska JB, Sheridan BS
PLoS Pathog. 2022 May;18(5):e1010586. doi: 10.1371/journal.ppat.1010586. Epub 2022 May 25.
PMID: 35613102